Notch signaling in oral squamous neoplasia

A facile one-step strategy for the generation of conditional knockout mice to explore the role of Notch1 in oroesophageal tumorigenesis

(2016) Masita Mandasari et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

NOTCH3 Is Induced in Cancer-Associated Fibroblasts and Promotes Angiogenesis in Oral Squamous Cell Carcinoma

(2016) Kou Kayamori et al.   PLoS One

Control of hair cell development by molecular pathways involving Atoh1, Hes1 and Hes5

(2015) Yi-Xun Su et al.   GENE

The opposing roles of NOTCH signalling in head and neck cancer: a mini review

(2015) LF Yap et al.   ORAL DISEASES

Whole Exome Sequencing Identifies Frequent Somatic Mutations in Cell-Cell Adhesion Genes in Chinese Patients with Lung Squamous Cell Carcinoma

(2015) Chenguang Li et al.   Scientific Reports

Mutational landscapes of tongue carcinoma reveal recurrent mutations in genes of therapeutic and prognostic relevance

(2015) Andre Luiz Vettore et al.   Genome Medicine

Mutational Landscape of Aggressive Cutaneous Squamous Cell Carcinoma

(2014) C. R. Pickering et al.   CLINICAL CANCER RESEARCH

NOTCH1 Mutations Occur Early during Cutaneous Squamous Cell Carcinogenesis

(2014) Andrew P. South et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Identification of genomic alterations in oesophageal squamous cell cancer

(2014) Yongmei Song et al.   NATURE

Discovery and saturation analysis of cancer genes across 21 tumour types

(2014) Michael S. Lawrence et al.   NATURE

Common and Complex Notch1 Mutations in Chinese Oral Squamous Cell Carcinoma

(2013) Xiaomeng Song et al.   CLINICAL CANCER RESEARCH

Stem cells living with a Notch

(2013) U. Koch et al.   DEVELOPMENT

Landscape of genomic alterations in cervical carcinomas

(2013) Akinyemi I. Ojesina et al.   NATURE

Integrative Genomic Characterization of Oral Squamous Cell Carcinoma Identifies Frequent Somatic Drivers

(2013) C. R. Pickering et al.   Cancer Discovery

Aberrant epidermal differentiation and disrupted  Np63/Notch regulatory axis in Ets1 transgenic mice

(2013) S. S. Chin et al.   Biology Open

Reduction of NOTCH1 expression pertains to maturation abnormalities of keratinocytes in squamous neoplasms

(2012) Kei Sakamoto et al.   LABORATORY INVESTIGATION

Comprehensive genomic characterization of squamous cell lung cancers

(2012)   NATURE

Endocytosis by Numb breaks Notch symmetry at cytokinesis

(2012) Lydie Couturier et al.   NATURE CELL BIOLOGY

Notch ligand endocytosis: Mechanistic basis of signaling activity

(2012) Abdiwahab A. Musse et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Down-regulation of keratin 4 and keratin 13 expression in oral squamous cell carcinoma and epithelial dysplasia: a clue for histopathogenesis

(2011) Kei Sakamoto et al.   HISTOPATHOLOGY

Asymmetric cell divisions promote Notch-dependent epidermal differentiation

(2011) Scott E. Williams et al.   NATURE

Loss-of-function mutations in Notch receptors in cutaneous and lung squamous cell carcinoma

(2011) N. J. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Exome Sequencing of Head and Neck Squamous Cell Carcinoma Reveals Inactivating Mutations in NOTCH1

(2011) N. Agrawal et al.   SCIENCE

The Mutational Landscape of Head and Neck Squamous Cell Carcinoma

(2011) N. Stransky et al.   SCIENCE

Cis-interactions between Notch and Delta generate mutually exclusive signalling states

(2010) David Sprinzak et al.   NATURE

Origin and evolution of the Notch signalling pathway: an overview from eukaryotic genomes

(2009) Eve Gazave et al.   BMC EVOLUTIONARY BIOLOGY

Epidermal Notch1 Loss Promotes Skin Tumorigenesis by Impacting the Stromal Microenvironment

(2009) Shadmehr Demehri et al.   CANCER CELL

The Canonical Notch Signaling Pathway: Unfolding the Activation Mechanism

(2009) Raphael Kopan et al.   CELL

Directional Delta and Notch trafficking in Sara endosomes during asymmetric cell division

(2009) F. Coumailleau et al.   NATURE

Genome-wide analysis of Notch signalling in Drosophila by transgenic RNAi

(2009) Jennifer L. Mummery-Widmer et al.   NATURE

Notch-Deficient Skin Induces a Lethal Systemic B-Lymphoproliferative Disorder by Secreting TSLP, a Sentinel for Epidermal Integrity

(2008) Shadmehr Demehri et al.   PLOS BIOLOGY