NOTCH3 Is Induced in Cancer-Associated Fibroblasts and Promotes Angiogenesis in Oral Squamous Cell Carcinoma

Targeting Notch Signaling with a Notch2/Notch3 Antagonist (Tarextumab) Inhibits Tumor Growth and Decreases Tumor-Initiating Cell Frequency

(2015) W.-C. Yen et al.   CLINICAL CANCER RESEARCH

The complex mural cell: Pericyte function in health and disease

(2015) Christian G.M. van Dijk et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Pericytes: Properties, Functions and Applications in Tissue Engineering

(2015) Beyza Gökçinar-Yagci et al.   Stem Cell Reviews and Reports

Pericytes: Properties, Functions and Applications in Tissue Engineering

(2015) Beyza Gökçinar-Yagci et al.   Stem Cell Reviews and Reports

Nuclear Notch3 Expression is Associated with Tumor Recurrence in Patients with Stage II and III Colorectal Cancer

(2014) Tsuyoshi Ozawa et al.   ANNALS OF SURGICAL ONCOLOGY

Notch functions in developmental and tumour angiogenesis by diverse mechanisms1

(2014) Thaned Kangsamaksin et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

From Fly Wings to Targeted Cancer Therapies: A Centennial for Notch Signaling

(2014) Panagiotis Ntziachristos et al.   CANCER CELL

Notch signaling in blood vessels: from morphogenesis to homeostasis

(2014) Ping Zhang et al.   Science China-Life Sciences

Cancer cell-derived lymphotoxin mediates reciprocal tumour-stromal interactions in human ovarian cancer by inducing CXCL11 in fibroblasts

(2013) Tat-San Lau et al.   JOURNAL OF PATHOLOGY

Role of p63 and the Notch pathway in cochlea development and sensorineural deafness

(2013) A. Terrinoni et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

‘Cancer associated fibroblasts’ – more than meets the eye

(2013) Shalom Madar et al.   TRENDS IN MOLECULAR MEDICINE

Integrative Genomic Characterization of Oral Squamous Cell Carcinoma Identifies Frequent Somatic Drivers

(2013) C. R. Pickering et al.   Cancer Discovery

Patterning and cell fate in the inner ear: a case for Notch in the chicken embryo

(2012) Joana Neves et al.   DEVELOPMENT GROWTH & DIFFERENTIATION

Tumor cell and carcinoma-associated fibroblast interaction regulates matrix metalloproteinases and their inhibitors in oral squamous cell carcinoma

(2012) Alexandra Fullár et al.   EXPERIMENTAL CELL RESEARCH

Implication of Tumor Microenvironment in Chemoresistance: Tumor-Associated Stromal Cells Protect Tumor Cells from Cell Death

(2012) Magali Castells et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Cancer-associated fibroblasts and CD163-positive macrophages in oral squamous cell carcinoma: their clinicopathological and prognostic significance

(2012) Nobuyuki Fujii et al.   JOURNAL OF ORAL PATHOLOGY & MEDICINE

Reduction of NOTCH1 expression pertains to maturation abnormalities of keratinocytes in squamous neoplasms

(2012) Kei Sakamoto et al.   LABORATORY INVESTIGATION

Notch3 and Hey-1 as Prognostic Biomarkers in Pancreatic Adenocarcinoma

(2012) Christopher D. Mann et al.   PLoS One

Notch signaling in human development and disease

(2012) Andrea L. Penton et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Uses of thein vitroendothelial–fibroblast organotypic co-culture assay in angiogenesis research : Figure 1

(2011) Clare Hetheridge et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Notch Activation of Jagged1 Contributes to the Assembly of the Arterial Wall

(2011) Lauren J. Manderfield et al.   CIRCULATION

Myofibroblasts in the stroma of oral cancer promote tumorigenesis via secretion of activin A

(2011) Lays M. Sobral et al.   ORAL ONCOLOGY

Another NOTCH for Cancer

(2011) R. H. Brakenhoff   SCIENCE

Exome Sequencing of Head and Neck Squamous Cell Carcinoma Reveals Inactivating Mutations in NOTCH1

(2011) N. Agrawal et al.   SCIENCE

Notch3 Overexpression Is Related to the Recurrence of Ovarian Cancer and Confers Resistance to Carboplatin

(2010) Joon Tae Park et al.   AMERICAN JOURNAL OF PATHOLOGY

Pathogenesis of CADASIL

(2010) Anne Joutel   BIOESSAYS

Notch3 Is Critical for Proper Angiogenesis and Mural Cell Investment

(2010) Hua Liu et al.   CIRCULATION RESEARCH

Activation of Notch signaling in human tongue carcinoma

(2010) Tong-Han Zhang et al.   JOURNAL OF ORAL PATHOLOGY & MEDICINE

Cancer-associated fibroblasts, a parameter of the tumor microenvironment, overcomes carcinoma-associated parameters in the prognosis of patients with mobile tongue cancer

(2010) Ibrahim O. Bello et al.   ORAL ONCOLOGY

Roles of Interleukin-6 and Parathyroid Hormone-Related Peptide in Osteoclast Formation Associated with Oral Cancers

(2009) Kou Kayamori et al.   AMERICAN JOURNAL OF PATHOLOGY

Cancer Statistics, 2009

(2009) A. Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

The Wnt Target Jagged-1 Mediates the Activation of Notch Signaling by Progastrin in Human Colorectal Cancer Cells

(2009) J. Pannequin et al.   CANCER RESEARCH

The Canonical Notch Signaling Pathway: Unfolding the Activation Mechanism

(2009) Raphael Kopan et al.   CELL

NOTCH3 Expression Is Induced in Mural Cells Through an Autoregulatory Loop That Requires Endothelial-Expressed JAGGED1

(2009) Hua Liu et al.   CIRCULATION RESEARCH

Regulation of angiogenesis by homotypic and heterotypic notch signalling in endothelial cells and pericytes: from basic research to potential therapies

(2008) Richard C. A. Sainson et al.   ANGIOGENESIS

Differential gene expression in a coculture model of angiogenesis reveals modulation of select pathways and a role for Notch signaling

(2008) Brenda Lilly et al.   PHYSIOLOGICAL GENOMICS

Regulation of HGF and SDF-1 expression by oral fibroblasts – Implications for invasion of oral cancer

(2007) Aisling J. Daly et al.   ORAL ONCOLOGY

Mutual paracrine effects of oral squamous cell carcinoma cells and normal oral fibroblasts: Induction of fibroblast to myofibroblast transdifferentiation and modulation of tumor cell proliferation

(2007) Michele G. Kellermann et al.   ORAL ONCOLOGY