Article
Infectious Diseases
Cori L. Dennison, Lorena B. de Oliveira, Lucia A. de O. Fraga, Rosemary S. E. Lima, Jose A. Ferreira, Julie A. Clennon, Laura de Mondesert, Jessica Stephens, Erica B. Magueta, Alexandre Castelo Branco, Michelle de Carvalho Rezende, Deborah Negrao-Correa, Maria Aparecida de Faria Grossi, Jessica K. Fairley
Summary: The study identified associations between helminth infections and vitamin D deficiency with an increased risk of leprosy. Iron deficiency and vitamin A deficiency were not found to be associated with leprosy in this study.
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
(2021)
Article
Gastroenterology & Hepatology
Manasi Agrawal, Kristine H. H. Allin, Aske T. T. Iversen, Saurabh Mehandru, Jean-Frederic Colombel, Tine Jess
Summary: According to this study, early-life exposure to mebendazole is associated with increased risk of adult-onset UC, but not Crohn's disease. This suggests the importance of early-life exposures in shaping the risk of IBD later in life.
AMERICAN JOURNAL OF GASTROENTEROLOGY
(2022)
Article
Multidisciplinary Sciences
Alice E. Law, Rebecca K. Shears, Andrea A. Lopez Rodas, Richard K. Grencis, Philip J. Cooper, Daniel R. Neill, Aras Kadioglu
Summary: Co-infection with Streptococcus pneumoniae and intestinal helminths is associated with increased carriage density and dissemination of pneumococcus, suggesting that treating helminth infections may be a cost-effective method for reducing the burden of pneumococcal disease in lower-income countries.
SCIENTIFIC REPORTS
(2021)
Article
Pharmacology & Pharmacy
Abimbola O. Aro, Ibukun M. Famuyide, Ademola A. Oyagbemi, Prudence N. Kabongo-Kayoka, Lyndy J. McGaw
Summary: Tuberculosis (TB) and helminth infections are globally important diseases that affect approximately one-third of the global population. The acetone extract and fractions of Psychotria capensis show antimycobacterial and anthelmintic activities, with low cytotoxicity. However, the hexane fraction exhibits the best dual anthelmintic and antimycobacterial activity.
FRONTIERS IN PHARMACOLOGY
(2022)
Article
Zoology
Amanda Caroline Dudczak, Gabriel Massaccesi De la Torre, Lorena Euclydes, Karla Magalhaes Campiao
Summary: Studying antagonistic networks among anurans reveals the influence of body size and life habits on network structure and stability, offering insights into the key species shaping these interactions within ecosystems.
INTEGRATIVE ZOOLOGY
(2022)
Article
Parasitology
M. J. Evans, Y. Corripio-Miyar, A. Hayward, F. Kenyon, T. N. McNeilly, D. H. Nussey
Summary: Gastrointestinal nematodes have significant impacts on sheep production and their interactions can affect the epidemiology and clinical impacts of infection. This study found strong evidence for antagonistic interactions between co-infecting GIN species in sheep, with the presence of one species leading to a decrease in the number of worms of the other species. The extent of these interactions varied between parasite species and was dependent on the infectious dose. These findings highlight the importance of studying GIN co-infections for epidemiological and clinical research.
VETERINARY PARASITOLOGY
(2023)
Review
Immunology
Xi Liu, Yuyun Jiang, Jixian Ye, Xuefeng Wang
Summary: The pathogenesis of NAFLD involves abnormal glycolipid metabolism, inflammation, and gut dysbiosis. Helminths and their products can treat or relieve NAFLD-related diseases by promoting glycolipid metabolism homeostasis, regulating inflammation, and restoring the balance of gut microbiota.
FRONTIERS IN IMMUNOLOGY
(2022)
Review
Immunology
Oyebola O. Oyesola, Camila Oliveira Silva Souza, P'ng Loke
Summary: Helminth infections affect over 2 billion people worldwide, with host genetics and environmental factors playing critical roles in regulating immune responses. Studying the interactions between environment and genetic factors in helminth infections could lead to the development of new preventive and therapeutic options.
FRONTIERS IN IMMUNOLOGY
(2022)
Review
Endocrinology & Metabolism
Claire Rennie, Ritin Fernandez, Sheila Donnelly, Kristine C. Y. McGrath
Summary: This systematic review and meta-analysis indicates that helminth infection may improve metabolic outcomes in human populations, with live infection with S. mansoni showing the most significant positive changes.
FRONTIERS IN ENDOCRINOLOGY
(2021)
Article
Multidisciplinary Sciences
Dagmara Wezyk, Karolina Romanczuk, Anna Rodo, Dziyana Kavalevich, Anna Bajer
Summary: Co-infections with Dirofilaria repens and Babesia canis are rare but pose a risk in dogs in central Poland. Dogs infected with D. repens showed no major alterations in blood parameters, while those infected with B. canis suffered from anaemia and organ dysfunction. Dogs co-infected with both parasites showed milder alterations in blood parameters, and the expression of immune response genes varied depending on the type and severity of infection.
SCIENTIFIC REPORTS
(2023)
Article
Biology
Angela H. Valente, Karen M. R. Jensen, Laura J. Myhill, Ling Zhu, Caroline M. J. Mentzel, Lukasz Krych, Henrik T. Simonsen, Josue L. Castro-Mejia, Alex Gobbi, Knud Erik Bach Knudsen, Dennis S. Nielsen, Stig M. Thamsborg, Andrew R. Williams
Summary: Highly processed diets can cause inflammation and gut microbiome dysbiosis, while health-promoting dietary components such as phytonutrients and fermentable fibers are thought to promote a healthy microbiome and balanced mucosal immunity. However, unexpectedly, the addition of chicory leaves rendered mice susceptible to enteric helminth infection. Chicory is rich in fibers and bioactive compounds that may be beneficial for gut health.
Review
Immunology
Amr Ehab El-Qushayri, Abdullah Reda, Jaffer Shah
Summary: This paper aimed to study the characteristics, laboratory data, and outcomes of monkeypox virus (MPV) and COVID-19 co-infection. Three male patients with multiple comorbid conditions and a history of sexual activity with men prior to infection were diagnosed with PCR and admitted to the hospital. All cases were effectively managed and recovered well during hospitalization. Future investigations with larger sample sizes are needed to establish a definitive cause-effect association between SARS-CoV-2 and MPV co-infection and patient outcomes.
FRONTIERS IN IMMUNOLOGY
(2022)
Article
Agriculture, Dairy & Animal Science
Luciana L. Dias De Castro, Gerson A. Oliveira Junior, Bruno Costa Perez, Minos E. Carvalho, Edneia A. De Souza Ramos, Jose Bento S. Ferraz, Marcelo Beltrao Molento
Summary: This study identified genomic regions associated with Cyathostomins infection in horses through genomic-wide association analysis. Candidate genes related to fecal egg count and hematological parameters were discovered, providing insights for animal breeding activities and reducing losses caused by parasite infections.
ANIMAL BIOTECHNOLOGY
(2022)
Article
Ecology
Caroline K. Glidden, Courtney A. C. Coon, Brianna R. Beechler, Chase McNulty, Vanessa O. Ezenwa, Anna E. Jolles
Summary: The dynamics of directly transmitted pathogens in natural populations are influenced by host traits, pathogen biology, and interactions among pathogens within a host. This study on wild African buffalo reveals that pathogen associations play a key role in determining infection risk, while host traits and season also impact pathogen dynamics.
JOURNAL OF ANIMAL ECOLOGY
(2021)
Article
Infectious Diseases
Sri Linuwih Menaldi, Anastasia Asylia Dinakrisma, Hok Bing Thio, Iris Rengganis, Salma Oktaria
Summary: This case report highlights a unique case of type 2 leprosy reaction with septic shock-like features induced by helminth infection in a previously treated patient. Helminth infections can trigger severe type 2 leprosy reactions that mimic septic shock, posing diagnostic and treatment challenges that require awareness among health professionals in endemic regions.
PLOS NEGLECTED TROPICAL DISEASES
(2021)