Article
Gastroenterology & Hepatology
Dustin A. Carlson, Christina Shehata, Nirmala Gonsalves, Ikuo Hirano, Stephanie Peterson, Jacqueline Prescott, Domenico A. Farina, Jacob M. Schauer, Wenjun Kou, Peter J. Kahrilas, John E. Pandolfino
Summary: This study evaluated the characteristics of secondary peristalsis in patients with EoE and found that abnormal esophageal contractions were associated with disease severity.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
(2022)
Article
Gastroenterology & Hepatology
Katelyn E. Madigan, J. Shawn Smith, Joni K. Evans, Steven B. Clayton
Summary: This study found that an elevated average maximum intrabolus pressure (AM-IBP) is associated with abnormal findings of esophageal tablet retention and/or bolus stasis. An abnormal AM-IBP was also found to be associated with a higher probability of retaining liquid bolus or barium tablet arrest, as well as esophageal dysmotility.
BMC GASTROENTEROLOGY
(2022)
Review
Pediatrics
Charmaine Chai, Usha Krishnan
Summary: Eosinophilic esophagitis (EoE) is a chronic inflammatory disease characterized by mucosal inflammation with eosinophils, resulting from antigen exposure. It can cause various symptoms such as dysphagia, chest pain, and vomiting. Although the diagnosis is based on histological findings, there is a discrepancy between symptom severity and the degree of esophageal eosinophilia.
FRONTIERS IN PEDIATRICS
(2022)
Review
Gastroenterology & Hepatology
Sumana B. Reddy, Corey J. Ketchem, Michael K. Dougherty, Swathi Eluri, Evan S. Dellon
Summary: Non-specific motility disorders are common in patients with eosinophilic esophagitis (EoE), but major motility disorders are rare. Further studies are needed to determine the relationship between eosinophilic infiltration and the clinical relevance of abnormal esophageal motility findings in this population.
NEUROGASTROENTEROLOGY AND MOTILITY
(2023)
Article
Surgery
Chloe W. Caudell, Ethan P. Covil, John W. Gilpin, Brian Hodgens, Alex Ewing, Shanu N. Kothari
Summary: The study evaluates the use of Minimally Invasive Marshmallow Swallow Study (MSS) as a screening technique and its correlation with High Resolution Manometry (HRM) results and post-operative dysphagia. The results suggest that MSS is effective in ruling out major esophageal motility disorders and reducing the need for invasive HRM.
AMERICAN JOURNAL OF SURGERY
(2022)
Article
Gastroenterology & Hepatology
Deepika Razia, Amy Trahan, Chengcheng Hu, Luca Giulini, Ross M. Bremner, Sumeet K. Mittal
Summary: The study aimed to investigate the correlation between upright and prone bolus transit time (BTT) on barium esophagography (BE), esophageal peristalsis on high-resolution manometry (HRM), and self-reported dysphagia in patients. The results showed that prone BTT correlated with the proportion of normal esophageal swallows and dysphagia.
JOURNAL OF CLINICAL GASTROENTEROLOGY
(2022)
Article
Medicine, General & Internal
Serkan Bilgin, Ahmet Kayali, Adnan Yamanoglu, Huseyin Acar, Zeynep Karakaya, Firdevs Topal, Elif Saritas Yuksel, Fatih Esad Topal
Summary: In patients with dysphagia and normal CM, over 40% were completely asymptomatic at follow-up, while less than half reported significant symptoms, with the remaining responders admitting to moderate to mild symptoms.
Article
Medicine, General & Internal
Mariko Hara, Rumi Ueha, Taku Sato, Takao Goto, Ayumi Yoshizaki, Hayakazu Sumida, Shinichi Sato, Tatsuya Yamasoba
Summary: Systemic sclerosis is often associated with dysphagia and esophageal dysmotility. This study evaluated the association between dysphagia and esophageal dysmotility in patients with systemic sclerosis and identified risk factors. The results showed that dysphagia was associated with autoantibody positivity and older age, while there were no identified risk factors for esophageal dysmotility. No correlation was found between dysphagia and esophageal dysmotility.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Surgery
Giuseppe Zambito, Robert Roether, Brittany Kern, Ryan Conway, David Scheeres, Amy Banks-Venegoni
Summary: This study found that BE has lower concordance with HRM in diagnosing esophageal dysmotility, and therefore should not be used as a substitute for HRM in assessing pre-operative motility in patients undergoing anti-reflux surgery.
AMERICAN JOURNAL OF SURGERY
(2021)
Article
Medicine, General & Internal
Akshat Ritesh Shah, Maaz S. Arif, We'am Hussain, Sangeeta Agrawal
Summary: This report presents a case of an unusual complication during high-resolution manometry testing, emphasizing the importance of caution for clinicians during the procedure.
CUREUS JOURNAL OF MEDICAL SCIENCE
(2022)
Article
Medicine, General & Internal
Asmaa Hegazy, Fahad Aleidan, Saitah AlShammari, Raghad Alhindi, Shahid Bashir
Summary: This case report describes a young adult who was initially diagnosed with dysphagia and later diagnosed with SLE. The patient's symptoms were attributed to SLE based on serology results, after ruling out other rheumatological and non-rheumatological conditions. Dysphagia is rarely reported as an initial symptom of SLE.
CUREUS JOURNAL OF MEDICAL SCIENCE
(2023)
Article
Cardiac & Cardiovascular Systems
Luca Giulini, Sumeet K. Mittal, Takahiro Masuda, Deepika Razia, Mate Csucska, Rajat Walia, Michael A. Smith, Ross M. Bremner
Summary: Esophageal peristalsis can improve after lung transplant, especially in patients with obstructive lung disease or pulmonary arterial hypertension. However, patients with restrictive lung disease and scleroderma are unlikely to experience peristalsis improvement. Subjective esophagram assessment may help predict peristalsis improvement in patients with restrictive lung disease without scleroderma.
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
(2022)
Review
Pharmacology & Pharmacy
Sawangpong Jandee, Annelies Geeraerts, Hannelore Geysen, Nathalie Rommel, Jan Tack, Tim Vanuytsel
Summary: Esophageal hypomotility, particularly ineffective esophageal motility according to the Chicago criteria, is a common motility disorder diagnosed on high resolution manometry. Most patients present with GERD symptoms or dysphagia. Prokinetic agents are commonly prescribed but their beneficial effects are limited to certain drugs.
FRONTIERS IN PHARMACOLOGY
(2021)
Article
Medicine, General & Internal
Ryusei Nishi, Haruka Amitani, Kazumasa Hamada, Takamasa Fukumoto, Ryuichi Kato, Takako Yamamoto, Yuuki Fuku, Kenichiro Sagiyama, Akihiro Asakawa
Summary: Idiopathic achalasia is a rare esophageal disorder characterized by progressive dysphagia and high lower esophageal sphincter pressure. This case report highlights the importance of considering achalasia when patients present with persistent symptoms, even if initially excluded. Medication is not a definitive treatment, and surgical intervention may be necessary for recovery. The psychosomatic approach can also be beneficial in managing symptoms.
Article
Medicine, Research & Experimental
Daniela Pop, Radu Samuel Pop, Teodora Surdea Blaga, Liliana David, Carmen Asavoaie, Marcel Tantau, Dan Lucian Dumitrascu, Dorin Farcau
Summary: The aim of this study was to explore the diagnosis and treatment of achalasia in children using esophageal HRM. Clinical data and investigation results of seven children with achalasia at a pediatric tertiary center were analyzed. All patients underwent evaluation with conventional esophageal manometry and/or esophageal HRM, and a multidisciplinary team provided diagnosis and treatment. Four children with type II achalasia were treated with POEM and three patients received pneumatic dilations. Overall, achalasia is a rare but challenging condition in children, and diagnosis is based on clinical suspicion, upper digestive endoscopy, and confirmation with esophageal HRM. Treatment should be individualized based on the type of achalasia, age of children, and severity.
EXPERIMENTAL AND THERAPEUTIC MEDICINE
(2023)