Continuous treatment with odanacatib for up to 8 years in postmenopausal women with low bone mineral density: a phase 2 study

Sustained Modeling-Based Bone Formation During Adulthood in Cynomolgus Monkeys May Contribute to Continuous BMD Gains With Denosumab

(2015) Michael S Ominsky et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Odanacatib increases mineralized callus during fracture healing in a rabbit ulnar osteotomy model

(2015) Brenda L. Pennypacker et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Inhibition of Cathepsin K Increases Modeling-Based Bone Formation, and Improves Cortical Dimension and Strength in Adult Ovariectomized Monkeys

(2014) Brenda L Pennypacker et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Effects of Odanacatib on the Radius and Tibia of Postmenopausal Women: Improvements in Bone Geometry, Microarchitecture, and Estimated Bone Strength

(2014) Angela M Cheung et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Characterizing microarchitectural changes at the distal radius and tibia in postmenopausal women using HR-pQCT

(2014) C. E. Kawalilak et al.   OSTEOPOROSIS INTERNATIONAL

Management of osteoporosis of the oldest old

(2014) R. Rizzoli et al.   OSTEOPOROSIS INTERNATIONAL

Implications of Osteoblast-Osteoclast Interactions in the Management of Osteoporosis by Antiresorptive Agents Denosumab and Odanacatib

(2014) Natalie A. Sims et al.   Current Osteoporosis Reports

The Bone Resorption Inhibitors Odanacatib and Alendronate Affect Post-Osteoclastic Events Differently in Ovariectomized Rabbits

(2013) Pia Rosgaard Jensen et al.   CALCIFIED TISSUE INTERNATIONAL

Bone Density, Turnover, and Estimated Strength in Postmenopausal Women Treated With Odanacatib: A Randomized Trial

(2013) Kim Brixen et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Bisphosphonate Therapy for Osteoporosis: Benefits, Risks, and Drug Holiday

(2012) Michael McClung et al.   AMERICAN JOURNAL OF MEDICINE

Denosumab, a RANK Ligand Inhibitor, for Postmenopausal Women with Osteoporosis

(2012) Emily E Sutton et al.   ANNALS OF PHARMACOTHERAPY

Odanacatib in the treatment of postmenopausal women with low bone mineral density: Five years of continued therapy in a phase 2 study

(2012) Bente Langdahl et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Bisphosphonates for Osteoporosis — Where Do We Go from Here?

(2012) Marcea Whitaker et al.   NEW ENGLAND JOURNAL OF MEDICINE

European guidance for the diagnosis and management of osteoporosis in postmenopausal women

(2012) J. A. Kanis et al.   OSTEOPOROSIS INTERNATIONAL

Odanacatib reduces bone turnover and increases bone mass in the lumbar spine of skeletally mature ovariectomized rhesus monkeys

(2011) Patricia J Masarachia et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Odanacatib treatment increases hip bone mass and cortical thickness by preserving endocortical bone formation and stimulating periosteal bone formation in the ovariectomized adult rhesus monkey

(2011) Tara Cusick et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Morphea-like skin reactions in patients treated with the cathepsin K inhibitor balicatib

(2011) Thomas M. Rnger et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Osteoporosis: now and the future

(2011) Tilman D Rachner et al.   LANCET

Denosumab and bisphosphonates: Different mechanisms of action and effects

(2010) Roland Baron et al.   BONE

Microarchitectural deterioration of cortical and trabecular bone: Differing effects of denosumab and alendronate

(2010) Ego Seeman et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Odanacatib in the treatment of postmenopausal women with low bone mineral density: Three-year continued therapy and resolution of effect

(2010) John A Eisman et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Effect of the Cathepsin K Inhibitor Odanacatib on Bone Resorption Biomarkers in Healthy Postmenopausal Women: Two Double-Blind, Randomized, Placebo-Controlled Phase I Studies

(2009) S A Stoch et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

The discovery of odanacatib (MK-0822), a selective inhibitor of cathepsin K

(2008) Jacques Yves Gauthier et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Bone density, strength, and formation in adult cathepsin K (−/−) mice

(2008) B. Pennypacker et al.   BONE

Drug-induced morphea: Report of a case induced by balicatib and review of the literature

(2008) Anna Peroni et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY