Intramolecular Long-Distance Nucleophilic Reactions as a Rapid Fluorogenic Switch Applicable to the Detection of Enzymatic Activity

A Chemical Strategy for the Cell-Based Detection of HDAC Activity

(2014) Himashinie V. K. Diyabalanage et al.   ACS Chemical Biology

Development of a Fluorogenic Probe Based on a DNA Staining Dye for Continuous Monitoring of the Histone Deacetylase Reaction

(2014) Masafumi Minoshima et al.   ANALYTICAL CHEMISTRY

Synthesis and evaluation of new NIR-fluorescent probes for cathepsin B: ICT versus FRET as a turn-ON mode-of-action

(2014) Einat Kisin-Finfer et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Bioorthogonal cyclization-mediated in situ self-assembly of small-molecule probes for imaging caspase activity in vivo

(2014) Deju Ye et al.   Nature Chemistry

Profiling Deacetylase Activities in Cell Lysates with Peptide Arrays and SAMDI Mass Spectrometry

(2013) Hsin-Yu Kuo et al.   ANALYTICAL CHEMISTRY

Hyperbranched Polyester-Based Fluorescent Probe for Histone Deacetylase via Aggregation-Induced Emission

(2013) Changmin Yu et al.   BIOMACROMOLECULES

Dissecting the Roles of the N- and C-Flanking Residues of Acetyllysine Substrates for SIRT1 Activity

(2013) Roman Meledin et al.   CHEMBIOCHEM

A fluorescent probe for detection of histone deacetylase activity based on aggregation-induced emission

(2012) Koushik Dhara et al.   CHEMICAL COMMUNICATIONS

Thiosuccinyl Peptides as Sirt5-Specific Inhibitors

(2012) Bin He et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Development of a Fluorogenic Probe with a Transesterification Switch for Detection of Histone Deacetylase Activity

(2012) Reisuke Baba et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The many faces of insulin-like peptide signalling in the brain

(2012) Ana M. Fernandez et al.   NATURE REVIEWS NEUROSCIENCE

Chemical Approaches To Understand the Language of Histone Modifications

(2011) Abhinav Dhall et al.   ACS Chemical Biology

Controlling Intracellular Macrocyclization for the Imaging of Protease Activity

(2011) Deju Ye et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Regulation of chromatin by histone modifications

(2011) Andrew J Bannister et al.   CELL RESEARCH

Sirt5 Is a NAD-Dependent Protein Lysine Demalonylase and Desuccinylase

(2011) J. Du et al.   SCIENCE

SIRT3 Substrate Specificity Determined by Peptide Arrays and Machine Learning

(2010) Brian C. Smith et al.   ACS Chemical Biology

Reversal of Histone Methylation: Biochemical and Molecular Mechanisms of Histone Demethylases

(2010) Nima Mosammaparast et al.   Annual Review of Biochemistry

Inhibitors to understand molecular mechanisms of NAD+-dependent deacetylases (sirtuins)

(2010) Michael Lawson et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Identification of lysine succinylation as a new post-translational modification

(2010) Zhihong Zhang et al.   Nature Chemical Biology

Histone modification patterns and epigenetic codes

(2009) Andreas Lennartsson et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Nϵ-Thioacetyl-Lysine-Containing Tri-, Tetra-, and Pentapeptides as SIRT1 and SIRT2 Inhibitors

(2009) Päivi H. Kiviranta et al.   JOURNAL OF MEDICINAL CHEMISTRY

Mechanisms and Molecular Probes of Sirtuins

(2008) Brian C. Smith et al.   CHEMISTRY & BIOLOGY

Development of a New Nonpeptidic Self-Immolative Spacer. Application to the Design of Protease Sensing Fluorogenic Probes

(2008) Yves Meyer et al.   ORGANIC LETTERS

Fluorescence Imaging of Cellular Glutathione Using a Latent Rhodamine

(2008) Marcos M. Pires et al.   ORGANIC LETTERS