Lipid structure influences the ability of glucose monocorynomycolate to signal through Mincle

Immune sensing of microbial glycolipids and related conjugates by T cells and the pattern recognition receptors MCL and Mincle

(2016) Dylan G.M. Smith et al.   CARBOHYDRATE RESEARCH

Mincle-mediated anti-inflammatory IL-10 response counter-regulates IL-12 in vitro

(2016) Emmanuel C Patin et al.   Innate Immunity

Trehalose diester glycolipids are superior to the monoesters in binding to Mincle, activation of macrophages in vitro and adjuvant activity in vivo

(2016) Alexandra Huber et al.   Innate Immunity

Mincle Activation and the Syk/Card9 Signaling Axis Are Central to the Development of Autoimmune Disease of the Eye

(2016) Ellen J. Lee et al.   JOURNAL OF IMMUNOLOGY

The necrosome promotes pancreatic oncogenesis via CXCL1 and Mincle-induced immune suppression

(2016) Lena Seifert et al.   NATURE

Mycobacterium tuberculosis β-gentiobiosyl diacylglycerides signal through the pattern recognition receptor Mincle: total synthesis and structure activity relationships

(2015) Mark B. Richardson et al.   CHEMICAL COMMUNICATIONS

Corynomycolic acid-containing glycolipids signal through the pattern recognition receptor Mincle

(2015) Phillip L. van der Peet et al.   CHEMICAL COMMUNICATIONS

On One Leg: Trehalose Monoesters Activate Macrophages in a Mincle-Dependent Manner

(2014) Bridget L. Stocker et al.   CHEMBIOCHEM

Glycerol Monomycolate Is a Novel Ligand for the Human, but Not Mouse Macrophage Inducible C-type Lectin, Mincle

(2014) Yuki Hattori et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Vizantin Inhibits Endotoxin-Mediated Immune Responses via the TLR 4/MD-2 Complex

(2014) Masataka Oda et al.   JOURNAL OF IMMUNOLOGY

Differential Control of Mincle-Dependent Cord Factor Recognition and Macrophage Responses by the Transcription Factors C/EBPβ and HIF1α

(2014) Hanne Schoenen et al.   JOURNAL OF IMMUNOLOGY

MCL and Mincle: C-Type Lectin Receptors That Sense Damaged Self and Pathogen-Associated Molecular Patterns

(2014) Mark B. Richardson et al.   Frontiers in Immunology

Mechanism for Recognition of an Unusual Mycobacterial Glycolipid by the Macrophage Receptor Mincle

(2013) Hadar Feinberg et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural analysis for glycolipid recognition by the C-type lectins Mincle and MCL

(2013) A. Furukawa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Development of Vizantin, a Safe Immunostimulant, Based on the Structure–Activity Relationship of Trehalose-6,6′-dicorynomycolate

(2012) Hirofumi Yamamoto et al.   JOURNAL OF MEDICINAL CHEMISTRY

Purification and structure analysis of mycolic acids in Corynebacterium glutamicum

(2012) Yang Yang et al.   JOURNAL OF MICROBIOLOGY

A convenient synthesis of glucose monomycolate

(2011) Jacques Prandi   CARBOHYDRATE RESEARCH

Restoration of Pattern Recognition Receptor Costimulation to Treat Chromoblastomycosis, a Chronic Fungal Infection of the Skin

(2011) Maria da Glória Sousa et al.   Cell Host & Microbe

Long-Chain Lipids Are Required for the Innate Immune Recognition of Trehalose Diesters by Macrophages

(2011) Ashna A. Khan et al.   CHEMBIOCHEM

Cutting Edge: Mincle Is Essential for Recognition and Adjuvanticity of the Mycobacterial Cord Factor and its Synthetic Analog Trehalose-Dibehenate

(2010) H. Schoenen et al.   JOURNAL OF IMMUNOLOGY

The Dectin-2 family of C-type lectins in immunity and homeostasis

(2009) Lisa M. Graham et al.   CYTOKINE

Direct recognition of the mycobacterial glycolipid, trehalose dimycolate, by C-type lectin Mincle

(2009) Eri Ishikawa et al.   JOURNAL OF EXPERIMENTAL MEDICINE

C-type lectin Mincle is an activating receptor for pathogenic fungus,Malassezia

(2009) Sho Yamasaki et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mincle is an ITAM-coupled activating receptor that senses damaged cells

(2008) Sho Yamasaki et al.   NATURE IMMUNOLOGY