Synthesis and amylin receptor activity of glycomimetics of pramlintide using click chemistry

Discovery of the Once-Weekly Glucagon-Like Peptide-1 (GLP-1) Analogue Semaglutide

(2015) Jesper Lau et al.   JOURNAL OF MEDICINAL CHEMISTRY

Automated solid-phase peptide synthesis to obtain therapeutic peptides

(2014) Veronika Mäde et al.   Beilstein Journal of Organic Chemistry

Peptides Containing β-Amino Acid Patterns: Challenges and Successes in Medicinal Chemistry

(2014) Chiara Cabrele et al.   JOURNAL OF MEDICINAL CHEMISTRY

Data-Driven Synthesis of Proteolysis-Resistant Peptide Hormones

(2014) Michaela Prothiwa et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Convergent chemoenzymatic synthesis of a library of glycosylated analogues of pramlintide: structure–activity relationships for amylin receptor agonism

(2014) Renata Kowalczyk et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Glycosylation of Pramlintide: Synthetic Glycopeptides that Display In Vitro and In Vivo Activities as Amylin Receptor Agonists

(2013) Yusuke Tomabechi et al.   CHEMISTRY-A EUROPEAN JOURNAL

Activity of Pramlintide, Rat and Human Amylin but not Aβ1–42at Human Amylin Receptors

(2013) Joseph J. Gingell et al.   ENDOCRINOLOGY

Novel therapies for the management of type 2 diabetes mellitus: Part 1. Pramlintide and bromocriptine-QR (2型糖尿病治疗新药：第1部分.普兰林肽与溴隐亭-QR)

(2013) George Grunberger   Journal of Diabetes

Long-Acting Glucagon-Like Peptide 1 Receptor Agonists: A review of their efficacy and tolerability

(2011) A. J. Garber   DIABETES CARE

Islet Amyloid Polypeptide, Islet Amyloid, and Diabetes Mellitus

(2011) Per Westermark et al.   PHYSIOLOGICAL REVIEWS

An improved procedure for the preparation of aminomethyl polystyrene resin and its use in solid phase (peptide) synthesis

(2011) Paul W.R. Harris et al.   TETRAHEDRON LETTERS

The Role of Pramlintide for Weight Loss

(2010) Kaelen C Dunican et al.   ANNALS OF PHARMACOTHERAPY

Identification of glycosylated exendin-4 analogue with prolonged blood glucose-lowering activity through glycosylation scanning substitution

(2010) Taichi Ueda et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis of MUC1 Neoglycopeptides using efficient microwave-enhanced chaotrope-assisted click chemistry

(2010) Dong Jun Lee et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

A key role for tryptophan 84 in receptor activity-modifying protein 1 in the amylin 1 receptor

(2010) Joseph J. Gingell et al.   PEPTIDES

Strategies to prolong the plasma residence time of peptide drugs

(2010) Lisa Pollaro et al.   MedChemComm

One-step conversion of unprotected sugars to β-glycosyl azides using 2-chloroimidazolinium salt in aqueous solution

(2009) Tomonari Tanaka et al.   CHEMICAL COMMUNICATIONS

Global estimates of the prevalence of diabetes for 2010 and 2030

(2009) J.E. Shaw et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Chemoenzymatic Synthesis of Glycosylated Glucagon-like Peptide 1: Effect of Glycosylation on Proteolytic Resistance and in Vivo Blood Glucose-Lowering Activity

(2009) Taichi Ueda et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY