Marine AChE inhibitors isolated from Geodia barretti: natural compounds and their synthetic analogs

Novel Multitarget-Directed Ligands (MTDLs) with Acetylcholinesterase (AChE) Inhibitory and Serotonergic Subtype 4 Receptor (5-HT4R) Agonist Activities As Potential Agents against Alzheimer’s Disease: The Design of Donecopride

(2015) Christophe Rochais et al.   JOURNAL OF MEDICINAL CHEMISTRY

Multi-Target-Directed Ligands and other Therapeutic Strategies in the Search of a Real Solution for Alzheimer’s Disease

(2014) Angel Agis-Torres et al.   Current Neuropharmacology

Indolinone-based acetylcholinesterase inhibitors: Synthesis, biological activity and molecular modeling

(2014) Hamidreza Akrami et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Isolation and Synthesis of Pulmonarins A and B, Acetylcholinesterase Inhibitors from the Colonial Ascidian Synoicum pulmonaria

(2014) Margey Tadesse et al.   JOURNAL OF NATURAL PRODUCTS

Chemical Composition of the Bark of Tetrapterys mucronata and Identification of Acetylcholinesterase Inhibitory Constituents

(2014) Marcos Marçal Ferreira Queiroz et al.   JOURNAL OF NATURAL PRODUCTS

Application of Diffusion Growth Chambers for the Cultivation of Marine Sponge-Associated Bacteria

(2014) Georg Steinert et al.   MARINE BIOTECHNOLOGY

Recent progress in neuroactive marine natural products

(2014) Ryuichi Sakai et al.   NATURAL PRODUCT REPORTS

Cognitive and Neuropsychiatric Impairments in Alzheimer's Disease: Current Treatment Strategies

(2014) Anna Borisovskaya et al.   Current Psychiatry Reports

Nature: A Substantial Source of Auspicious Substances with Acetylcholinesterase Inhibitory Action

(2013) Ilkay Orhan   Current Neuropharmacology

Total Syntheses of Eudistomins Y1-Y7by an Efficient One-Pot Process of Tandem Benzylic Oxidation and Aromatization of 1-Benzyl-3,4-dihydro-β-Carbolines

(2013) Tien Ha Trieu et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Antioxidant and Anti-Inflammatory Activities of Barettin

(2013) Karianne Lind et al.   Marine Drugs

Total Synthesis and Biological Activity of Marine Alkaloid Eudistomins Y1–Y7 and Their Analogues

(2013) Huijuan Jin et al.   Marine Drugs

Gold and BINOL-Phosphoric Acid Catalyzed Enantioselective Hydroamination/N-Sulfonyliminium Cyclization Cascade

(2013) Alex W. Gregory et al.   ORGANIC LETTERS

Prospective acetylcholinesterase inhibitory activity of indole and its analogs

(2012) Nantaka Khorana et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Lessons from the Past and Charting the Future of Marine Natural Products Drug Discovery and Chemical Biology

(2012) William H. Gerwick et al.   CHEMISTRY & BIOLOGY

Steroidal alkaloids from Holarrhena antidysenterica as acetylcholinesterase inhibitors and the investigation for structure–activity relationships

(2012) Zhong-Duo Yang et al.   LIFE SCIENCES

Drug Discovery from Marine Microbes

(2012) William H. Gerwick et al.   MICROBIAL ECOLOGY

Genomic insights into the marine sponge microbiome

(2012) Ute Hentschel et al.   NATURE REVIEWS MICROBIOLOGY

Structural insights into cholinesterases inhibition by harmane β-carbolinium derivatives: A kinetics – molecular modeling approach

(2012) Juliana M. Torres et al.   PHYTOCHEMISTRY

Synthesis and studies of two marine indole alkaloids, barettin and caulersin

(2012) J. Bergman   PHYTOCHEMISTRY REVIEWS

Heteroaromatic alkaloids, nakijinamines, from a sponge Suberites sp.

(2012) Yohei Takahashi et al.   TETRAHEDRON

Enantioselective total synthesis of eudistomidins G, H, and I

(2012) Haruaki Ishiyama et al.   TETRAHEDRON

Total Synthesis of (+)-7-Bromotrypargine and Unnatural Analogues: Biological Evaluation Uncovers Activity at CNS Targets of Therapeutic Relevance

(2011) John T. Brogan et al.   ACS Chemical Neuroscience

CHOLINESTERASES, A TARGET OF PHARMACOLOGY AND TOXICOLOGY

(2011) Miroslav Pohanka   BIOMEDICAL PAPERS-OLOMOUC

Tryptamine derivatives as novel non-nucleosidic inhibitors against hepatitis B virus

(2011) Shi-Jin Qu et al.   BIOORGANIC & MEDICINAL CHEMISTRY

New Structural Insights into Saraines A, B, and C, Macrocyclic Alkaloids from the Mediterranean Sponge Reniera (Haliclona) sarai

(2011) Andrea Defant et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Deconstruction of the α4β2 Nicotinic Acetylcholine Receptor Positive Allosteric Modulator Desformylflustrabromine

(2011) Nadezhda German et al.   JOURNAL OF MEDICINAL CHEMISTRY

Allosteric Modulator Desformylflustrabromine Relieves the Inhibition of α2β2 and α4β2 Nicotinic Acetylcholine Receptors by β-Amyloid1–42 Peptide

(2011) Anshul Pandya et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Statistical Research on Marine Natural Products Based on Data Obtained between 1985 and 2008

(2011) Gu-Ping Hu et al.   Marine Drugs

The synthesis of dehydrotryptophan and dehydrotryptophan-containing peptides

(2011) Harveen Kaur et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Synthesis and biological evaluation of a new series of berberine derivatives as dual inhibitors of acetylcholinesterase and butyrylcholinesterase

(2010) Ling Huang et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Evolution of cholinesterases in the animal kingdom

(2010) Leo Pezzementi et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Scalable Total Syntheses ofN-Linked Tryptamine Dimers by Direct Indole−Aniline Coupling: Psychotrimine and Kapakahines B and F

(2010) Timothy Newhouse et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Study of acetylcholinesterase inhibitors using CE with contactless conductivity detection

(2009) Aiping Schuchert-Shi et al.   ELECTROPHORESIS

Acetylcholinesterase and butyrylcholinesterase inhibition of ethanolic extract and monoterpenes from Pimpinella anisoides V Brig. (Apiaceae)

(2009) Federica Menichini et al.   FITOTERAPIA

Characterisation of a proposed internet synthesis of N,N-dimethyltryptamine using liquid chromatography/electrospray ionisation tandem mass spectrometry

(2009) Cláudia P.B. Martins et al.   JOURNAL OF CHROMATOGRAPHY A

Natural Products and their Derivatives as Cholinesterase Inhibitors in the Treatment of Neurodegenerative Disorders: An Update

(2008) Monica Loizzo et al.   CURRENT MEDICINAL CHEMISTRY

Butyrylcholinesterase, lipoxygenase inhibiting and antifungal alkaloids from isatis tinctoria

(2008) Ijaz Ahmad et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Total Synthesis of (±)-Psychotrimine

(2008) Timothy Newhouse et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY