Asymmetric synthesis of (−)-renieramycin T

Stereoselective Total Synthesis of (−)-Renieramycin T

(2016) Masashi Yokoya et al.   JOURNAL OF ORGANIC CHEMISTRY

Research Progress in Synthesis of Renieramycin-Type Alkaloids

(2015) Yuting Song et al.   CHINESE JOURNAL OF ORGANIC CHEMISTRY

Ecteinascidins. A review of the chemistry, biology and clinical utility of potent tetrahydroisoquinoline antitumor antibiotics

(2015) V. H. Le et al.   NATURAL PRODUCT REPORTS

New isoquinolinequinone alkaloids from the South China Sea nudibranch Jorunna funebris and its possible sponge-prey Xestospongia sp.

(2014) Wen-Fei He et al.   FITOTERAPIA

PM00104 (Zalypsis®): A Marine Derived Alkylating Agent

(2014) Bradley Petek et al.   MOLECULES

A rapid and efficient access to renieramycin-type alkaloids featuring a temperature-dependent stereoselective cyclization

(2014) Hao Liu et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Asymmetric Total Synthesis of (−)-Jorunnamycins A and C and (−)-Jorumycin from l-Tyrosine

(2013) Ruijiao Chen et al.   JOURNAL OF NATURAL PRODUCTS

Total Synthesis of Ecteinascidin 743

(2013) Fumiki Kawagishi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

An efficient synthesis of l -3,4,5-trioxygenated phenylalanine compounds from l -tyrosine

(2013) Ruijiao Chen et al.   TETRAHEDRON

Chemistry of renieramycins. Part 13: Isolation and structure of stabilized renieramycin type derivatives, renieramycins W–Y, from Philippine blue sponge Xestospongia sp., pretreated with potassium cyanide

(2012) Mari Tatsukawa et al.   TETRAHEDRON

Meta-omic Characterization of the Marine Invertebrate Microbial Consortium That Produces the Chemotherapeutic Natural Product ET-743

(2011) Christopher M. Rath et al.   ACS Chemical Biology

Recent Synthetic Approaches to 6,15-Iminoisoquino[3,2-b]3-benzazocine Compounds

(2010) Carmen Avendaño et al.   CHEMISTRY-A EUROPEAN JOURNAL

A simple and selective method for the O-AcCl removal using sodium borohydride

(2010) Emmanuelle Villedieu et al.   TETRAHEDRON LETTERS

A new approach to the synthesis of l-3-hydroxy-4-methoxy-5-methyl-phenylalanine derivatives from l-tyrosine

(2010) Ruijiao Chen et al.   TETRAHEDRON-ASYMMETRY

Zalypsis (PM00104) is a potent inducer of  -H2AX foci and reveals the importance of the C ring of trabectedin for transcription-coupled repair inhibition

(2009) J. Guirouilh-Barbat et al.   MOLECULAR CANCER THERAPEUTICS

Development of Yondelis® (trabectedin, ET-743). A semisynthetic process solves the supply problem

(2009) Carmen Cuevas et al.   NATURAL PRODUCT REPORTS

Chemistry of renieramycins. Part 7: Renieramycins T and U, novel renieramycin–ecteinascidin hybrid marine natural products from Thai sponge Xestospongia sp.

(2009) Naomi Daikuhara et al.   TETRAHEDRON LETTERS

Zalypsis: a novel marine-derived compound with potent antimyeloma activity that reveals high sensitivity of malignant plasma cells to DNA double-strand breaks

(2008) E. M. Ocio et al.   BLOOD

Synthetic Studies on Et-743. Assembly of the Pentacyclic Core and a Formal Total Synthesis

(2008) Dan Fishlock et al.   JOURNAL OF ORGANIC CHEMISTRY

Drug development from marine natural products

(2008) Tadeusz F. Molinski et al.   NATURE REVIEWS DRUG DISCOVERY