Prolyl-isomerase Pin1 controls Notch3 protein expression and regulates T-ALL progression

Pin1 promotes neuronal death in stroke by stabilizing Notch intracellular domain

(2015) Sang-Ha Baik et al.   ANNALS OF NEUROLOGY

RETRACTED: Role of stromal cells-mediated Notch-1 in the invasion of T-ALL cells

(2015) Congcong Yin et al.   EXPERIMENTAL CELL RESEARCH

Active Pin1 is a key target of all-trans retinoic acid in acute promyelocytic leukemia and breast cancer

(2015) Shuo Wei et al.   NATURE MEDICINE

The epigenetic factor BORIS/CTCFL regulates the NOTCH3 gene expression in cancer cells

(2014) Michele Zampieri et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

EGFR Blockade Enriches for Lung Cancer Stem-like Cells through Notch3-Dependent Signaling

(2014) R. R. Arasada et al.   CANCER RESEARCH

The Molecular Basis of Notch Signaling Regulation: A Complex Simplicity

(2014) R. Palermo et al.   CURRENT MOLECULAR MEDICINE

The γ-secretase inhibitor PF-03084014 combined with fludarabine antagonizes migration, invasion and angiogenesis in NOTCH1-mutated CLL cells

(2014) M López-Guerra et al.   LEUKEMIA

Notch and NF-kB signaling pathways regulate miR-223/FBXW7 axis in T-cell acute lymphoblastic leukemia

(2014) V Kumar et al.   LEUKEMIA

Regulation of mitochondrial apoptosis by Pin1 in cancer and neurodegeneration

(2014) Giovanni Sorrentino et al.   MITOCHONDRION

Numb-dependent integration of pre-TCR and p53 function in T-cell precursor development

(2014) N M Martin-Blanco et al.   Cell Death & Disease

Notch3/Jagged1 Circuitry Reinforces Notch Signaling and Sustains T-ALL

(2014) Maria Pelullo et al.   NEOPLASIA

Prolyl-isomerase Pin1 controls normal and cancer stem cells of the breast

(2013) Alessandra Rustighi et al.   EMBO Molecular Medicine

Notch1 is required for hypoxia-induced proliferation, invasion and chemoresistance of T-cell acute lymphoblastic leukemia cells

(2013) Jie Zou et al.   Journal of Hematology & Oncology

Therapeutic antibody targeting of Notch1 in T-acute lymphoblastic leukemia xenografts

(2013) V Agnusdei et al.   LEUKEMIA

The Significance of Notch1 Compared with Notch3 in High Metastasis and Poor Overall Survival in Hepatocellular Carcinoma

(2013) Liang Zhou et al.   PLoS One

Mutation profiling identifies numerous rare drug targets and distinct mutation patterns in different clinical subtypes of breast cancers

(2012) Libero Santarpia et al.   BREAST CANCER RESEARCH AND TREATMENT

Glucocorticoid sensitivity of T-cell lymphoblastic leukemia/lymphoma is associated with glucocorticoid receptor-mediated inhibition of Notch1 expression

(2012) S Cialfi et al.   LEUKEMIA

Negative Regulation of the Stability and Tumor Suppressor Function of Fbw7 by the Pin1 Prolyl Isomerase

(2012) Sang-Hyun Min et al.   MOLECULAR CELL

Systematic identification of genomic markers of drug sensitivity in cancer cells

(2012) Mathew J. Garnett et al.   NATURE

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

(2012) Jordi Barretina et al.   NATURE

Notch and disease: A growing field

(2012) Angeliki Louvi et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Notch is oncogenic dominant in T-cell acute lymphoblastic leukemia

(2011) R. M. Demarest et al.   BLOOD

Modulation of microRNA expression in human T-cell development: targeting of NOTCH3 by miR-150

(2011) M. Ghisi et al.   BLOOD

Integrated Transcript and Genome Analyses Reveal NKX2-1 and MEF2C as Potential Oncogenes in T Cell Acute Lymphoblastic Leukemia

(2011) Irene Homminga et al.   CANCER CELL

Acetylation controls Notch3 stability and function in T-cell leukemia

(2011) R Palermo et al.   ONCOGENE

Prolyl isomerase Pin1 as a molecular switch to determine the fate of phosphoproteins

(2011) Yih-Cherng Liou et al.   TRENDS IN BIOCHEMICAL SCIENCES

Notch3 in Human Breast Cancer Cell Lines Regulates Osteoblast-Cancer Cell Interactions and Osteolytic Bone Metastasis

(2010) Zhiyuan Zhang et al.   AMERICAN JOURNAL OF PATHOLOGY

Matrix Metalloproteinase-9 Promotes Chronic Lymphocytic Leukemia B Cell Survival through Its Hemopexin Domain

(2010) Javier Redondo-Muñoz et al.   CANCER CELL

Peptidyl-Prolyl Isomerase Pin1 Markedly Enhances the Oncogenic Activity of the Rel Proteins in the Nuclear Factor- B Family

(2009) G. Fan et al.   CANCER RESEARCH

Notch Signaling: The Core Pathway and Its Posttranslational Regulation

(2009) Mark E. Fortini   DEVELOPMENTAL CELL

Notch3 and pTα/pre-TCR sustain the in vivo function of naturally occurring regulatory T cells

(2009) Antonio F. Campese et al.   INTERNATIONAL IMMUNOLOGY

CCR7 signalling as an essential regulator of CNS infiltration in T-cell leukaemia

(2009) Silvia Buonamici et al.   NATURE

The prolyl-isomerase Pin1 is a Notch1 target that enhances Notch1 activation in cancer

(2009) Alessandra Rustighi et al.   NATURE CELL BIOLOGY

Differential subcellular localization regulates c-Cbl E3 ligase activity upon Notch3 protein in T-cell leukemia

(2009) S Checquolo et al.   ONCOGENE