Active Pin1 is a key target of all-trans retinoic acid in acute promyelocytic leukemia and breast cancer

Prolyl Isomerase Pin1 Acts Downstream of miR200c to Promote Cancer Stem-like Cell Traits in Breast Cancer

(2014) M.-L. Luo et al.   CANCER RESEARCH

Prolyl isomerase Pin1 in cancer

(2014) Zhimin Lu et al.   CELL RESEARCH

Pin1 inhibitors: Pitfalls, progress and cellular pharmacology

(2013) Jonathan D. Moore et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Improving acute promyelocytic leukemia (APL) outcome in developing countries through networking, results of the International Consortium on APL

(2013) E. M. Rego et al.   BLOOD

Molecular Pathways: Current Role and Future Directions of the Retinoic Acid Pathway in Cancer Prevention and Treatment

(2013) R. M. Connolly et al.   CLINICAL CANCER RESEARCH

Single-Agent Liposomal All-Trans-Retinoic Acid as Initial Therapy for Acute Promyelocytic Leukemia: 13-Year Follow-Up Data

(2013) Preetesh Jain et al.   Clinical Lymphoma Myeloma & Leukemia

Prolyl-isomerase Pin1 controls normal and cancer stem cells of the breast

(2013) Alessandra Rustighi et al.   EMBO Molecular Medicine

Uncoupling RARA transcriptional activation and degradation clarifies the bases for APL response to therapies

(2013) Julien Ablain et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Retinoic Acid and Arsenic Trioxide for Acute Promyelocytic Leukemia

(2013) Francesco Lo-Coco et al.   NEW ENGLAND JOURNAL OF MEDICINE

The rs2233678 Polymorphism in PIN1 Promoter Region Reduced Cancer Risk: A Meta-Analysis

(2013) Qi Li et al.   PLoS One

Cyclic AMP can promote APL progression and protect myeloid leukemia cells against anthracycline-induced apoptosis

(2013) G Gausdal et al.   Cell Death & Disease

Proline Isomer-Specific Antibodies Reveal the Early Pathogenic Tau Conformation in Alzheimer's Disease

(2012) Kazuhiro Nakamura et al.   CELL

Negative Regulation of the Stability and Tumor Suppressor Function of Fbw7 by the Pin1 Prolyl Isomerase

(2012) Sang-Hyun Min et al.   MOLECULAR CELL

ERK1/2-dependent phosphorylation and nuclear translocation of PKM2 promotes the Warburg effect

(2012) Weiwei Yang et al.   NATURE CELL BIOLOGY

Epigallocatechin-gallate Suppresses Tumorigenesis by Directly Targeting Pin1

(2011) D. V. Urusova et al.   Cancer Prevention Research

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Modern Approaches to Treating Acute Promyelocytic Leukemia

(2011) Miguel A. Sanz et al.   JOURNAL OF CLINICAL ONCOLOGY

(+)α-Tocopheryl succinate inhibits the mitochondrial respiratory chain complex I and is as effective as arsenic trioxide or ATRA against acute promyelocytic leukemia in vivo

(2011) G A S dos Santos et al.   LEUKEMIA

Regulation of Estrogen Receptor   N-Terminus Conformation and Function by Peptidyl Prolyl Isomerase Pin1

(2011) P. Rajbhandari et al.   MOLECULAR AND CELLULAR BIOLOGY

Death-Associated Protein Kinase 1 Phosphorylates Pin1 and Inhibits Its Prolyl Isomerase Activity and Cellular Function

(2011) Tae Ho Lee et al.   MOLECULAR CELL

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Randomized Phase II Trial of All-Trans-Retinoic Acid With Chemotherapy Based on Paclitaxel and Cisplatin As First-Line Treatment in Patients With Advanced Non–Small-Cell Lung Cancer

(2010) Oscar Arrieta et al.   JOURNAL OF CLINICAL ONCOLOGY

Retinoic acid regulates bone morphogenic protein signal duration by promoting the degradation of phosphorylated Smad1

(2010) N. Sheng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MolProbity: all-atom structure validation for macromolecular crystallography

(2009) Vincent B. Chen et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Inhibition of the Peptidyl-Prolyl-Isomerase Pin1 Enhances the Responses of Acute Myeloid Leukemia Cells to Retinoic Acid via Stabilization of RAR  and PML-RAR 

(2009) M. Gianni' et al.   CANCER RESEARCH

Pin1 Down-regulates Transforming Growth Factor-β (TGF-β) Signaling by Inducing Degradation of Smad Proteins

(2009) Ayako Nakano et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Randomized Double-Blind 2 × 2 Trial of Low-Dose Tamoxifen and Fenretinide for Breast Cancer Prevention in High-Risk Premenopausal Women

(2009) Andrea Decensi et al.   JOURNAL OF CLINICAL ONCOLOGY

Peptidyl-prolyl cis/trans isomerase Pin1 is critical for the regulation of PKB/Akt stability and activation phosphorylation

(2009) Y Liao et al.   ONCOGENE

Effects of All-Trans Retinoic Acid on Th1- and Th2-Related Chemokines Production in Monocytes

(2008) Yu-Chien Tsai et al.   INFLAMMATION

Cdk2 and Pin1 negatively regulate the transcriptional corepressor SMRT

(2008) Kristopher J. Stanya et al.   JOURNAL OF CELL BIOLOGY

Randomized Phase III Trial Comparing Bexarotene (L1069-49)/Cisplatin/Vinorelbine With Cisplatin/Vinorelbine in Chemotherapy-Naïve Patients With Advanced or Metastatic Non–Small-Cell Lung Cancer: SPIRIT I

(2008) Rodryg Ramlau et al.   JOURNAL OF CLINICAL ONCOLOGY

Prolyl isomerase Pin1 is highly expressed in Her2-positive breast cancer and regulates erbB2 protein stability

(2008) Prudence B Lam et al.   Molecular Cancer

The deubiquitinylation and localization of PTEN are regulated by a HAUSP–PML network

(2008) Min Sup Song et al.   NATURE

Eradication of acute promyelocytic leukemia-initiating cells through PML-RARA degradation

(2008) Rihab Nasr et al.   NATURE MEDICINE