A novel association of neuropilin-1 and MUC1 in pancreatic ductal adenocarcinoma: role in induction of VEGF signaling and angiogenesis

Neuropilins are multifunctional coreceptors involved in tumor initiation, growth, metastasis and immunity

(2015) Gerald J Prud'homme et al.   Oncotarget

A Phase Ib study evaluating MNRP1685A, a fully human anti-NRP1 monoclonal antibody, in combination with bevacizumab and paclitaxel in patients with advanced solid tumors

(2014) Amita Patnaik et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

A phase I study of the human monoclonal anti-NRP1 antibody MNRP1685A in patients with advanced solid tumors

(2014) Colin D. Weekes et al.   INVESTIGATIONAL NEW DRUGS

Immunohistological Insight into the Correlation between Neuropilin-1 and Epithelial-Mesenchymal Transition Markers in Epithelial Ovarian Cancer

(2014) Sirin A. I. Adham et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

MUC1 Enhances Tumor Progression and Contributes Toward Immunosuppression in a Mouse Model of Spontaneous Pancreatic Adenocarcinoma

(2014) T. L. Tinder et al.   JOURNAL OF IMMUNOLOGY

The use of a novel MUC1 antibody to identify cancer stem cells and circulating MUC1 in mice and patients with pancreatic cancer

(2013) Jennifer M. Curry et al.   JOURNAL OF SURGICAL ONCOLOGY

MUC1 induces drug resistance in pancreatic cancer cells via upregulation of multidrug resistance genes

(2013) S Nath et al.   Oncogenesis

Pharmacokinetic and Pharmacodynamic Analysis of Circulating Biomarkers of Anti-NRP1, a Novel Antiangiogenesis Agent, in Two Phase I Trials in Patients with Advanced Solid Tumors

(2012) Y. Xin et al.   CLINICAL CANCER RESEARCH

Cancer Stem Cells and Novel Targets for Antitumor Strategies

(2012) Gerald J. Prud’homme   CURRENT PHARMACEUTICAL DESIGN

Neuropilins: expression and roles in the epithelium

(2012) Jonathan R. L. Wild et al.   INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY

Autocrine VEGF–VEGFR2–Neuropilin-1 signaling promotes glioma stem-like cell viability and tumor growth

(2012) Petra Hamerlik et al.   JOURNAL OF EXPERIMENTAL MEDICINE

MUC1 regulates PDGFA expression during pancreatic cancer progression

(2012) M Sahraei et al.   ONCOGENE

Pancreatic Ductal Adenocarcinoma Mice Lacking Mucin 1 Have a Profound Defect in Tumor Growth and Metastasis

(2011) D. M. Besmer et al.   CANCER RESEARCH

A vascular niche and a VEGF–Nrp1 loop regulate the initiation and stemness of skin tumours

(2011) Benjamin Beck et al.   NATURE

Mucin 1 enhances the tumor angiogenic response by activation of the AKT signaling pathway

(2011) J K Woo et al.   ONCOGENE

Zebrafish Model: Worth Considering in Defining Tumor Angiogenesis

(2011) Karni S. Moshal et al.   TRENDS IN CARDIOVASCULAR MEDICINE

Discriminating Different Cancer Cells Using a Zebrafish in Vivo Assay

(2011) Karni S. Moshal et al.   Cancers

ERβ Impedes Prostate Cancer EMT by Destabilizing HIF-1α and Inhibiting VEGF-Mediated Snail Nuclear Localization: Implications for Gleason Grading

(2010) Paul Mak et al.   CANCER CELL

MUC1 enhances invasiveness of pancreatic cancer cells by inducing epithelial to mesenchymal transition

(2010) L D Roy et al.   ONCOGENE

Neuropilins in Tumor Biology

(2009) A. Bagri et al.   CLINICAL CANCER RESEARCH

Neuropilins: structure, function and role in disease

(2008) Caroline Pellet-Many et al.   BIOCHEMICAL JOURNAL