Neuropilins: expression and roles in the epithelium

Expression of class 3 semaphorins and their receptors in human breast neoplasia

(2015) Carolyn A Staton et al.   HISTOPATHOLOGY

Neuropilin and Neuropilin Associated Molecules as New Molecular Targets in Pancreatic Adenocarcinoma

(2012) Michael H. Muders   Anti-Cancer Agents in Medicinal Chemistry

Meta-analysis of immunohistochemical prognostic markers in resected pancreatic cancer

(2011) R A Smith et al.   BRITISH JOURNAL OF CANCER

Neuropilin-2 promotes branching morphogenesis in the mouse mammary gland

(2011) H. L. Goel et al.   DEVELOPMENT

Neuropilins are positive regulators of Hedgehog signal transduction

(2011) R. T. Hillman et al.   GENES & DEVELOPMENT

Neuropilin and liver fibrosis: Hitting three birds with one stone?

(2011) Juliane S. Troeger et al.   HEPATOLOGY

Neuropilin-1 is upregulated in hepatocellular carcinoma and contributes to tumour growth and vascular remodelling

(2011) Mathieu Bergé et al.   JOURNAL OF HEPATOLOGY

Neuropilin-1 Signaling through p130Cas Tyrosine Phosphorylation Is Essential for Growth Factor-Dependent Migration of Glioma and Endothelial Cells

(2011) I. M. Evans et al.   MOLECULAR AND CELLULAR BIOLOGY

Short-chain fatty acid level and field cancerization show opposing associations with enteroendocrine cell number and neuropilin expression in patients with colorectal adenoma

(2011) Danny CW Yu et al.   Molecular Cancer

Neuropilin-2 Expression Promotes TGF-β1-Mediated Epithelial to Mesenchymal Transition in Colorectal Cancer Cells

(2011) Camille Grandclement et al.   PLoS One

Neuropilin-1 regulates platelet-derived growth factor receptor signalling in mesenchymal stem cells

(2010) Stephen G. Ball et al.   BIOCHEMICAL JOURNAL

Hedgehog signaling and gastrointestinal cancer

(2010) Milena Saqui-Salces et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Neuropilin-1 antagonism in human carcinoma cells inhibits migration and enhances chemosensitivity

(2010) H Jia et al.   BRITISH JOURNAL OF CANCER

ERβ Impedes Prostate Cancer EMT by Destabilizing HIF-1α and Inhibiting VEGF-Mediated Snail Nuclear Localization: Implications for Gleason Grading

(2010) Paul Mak et al.   CANCER CELL

Autocrine VEGF Signaling Synergizes with EGFR in Tumor Cells to Promote Epithelial Cancer Development

(2010) Beate M. Lichtenberger et al.   CELL

Gene Expression of Neuropilin-1 and Its Receptors, VEGF/Semaphorin 3a, in Normal and Cancer Cells

(2010) Ding Haixia et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

Regulation of immune cell responses by semaphorins and their receptors

(2010) Hyota Takamatsu et al.   Cellular & Molecular Immunology

Genetic association of the neuropilin-1 gene with type 1 diabetes in children: Neuropilin-1 expression in pancreatic islets

(2010) Noaman M. Hasan et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Sema4C-Plexin B2 signalling modulates ureteric branching in developing kidney

(2010) Nina Perälä et al.   DIFFERENTIATION

Butyrate-rich Colonic Microenvironment Is a Relevant Selection Factor for Metabolically Adapted Tumor Cells

(2010) Jacinta Serpa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neuropilin-1 Mediates Divergent R-Smad Signaling and the Myofibroblast Phenotype

(2010) Ying Cao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neuropilin-1 promotes cirrhosis of the rodent and human liver by enhancing PDGF/TGF-β signaling in hepatic stellate cells

(2010) Sheng Cao et al.   JOURNAL OF CLINICAL INVESTIGATION

Histological and transcriptional study of angiogenesis and lymphangiogenesis in uninvolved skin, acute pinpoint lesions and established psoriasis plaques: An approach of vascular development chronology in psoriasis

(2010) Audrey Henno et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Butyrate suppresses expression of neuropilin I in colorectal cell lines through inhibition of Sp1 transactivation

(2010) Danny CW Yu et al.   Molecular Cancer

Expression of Neuropilin-2 in salivary adenoid cystic carcinoma: Its implication in tumor progression and angiogenesis

(2010) Yu Cai et al.   PATHOLOGY RESEARCH AND PRACTICE

Inhibition of Neuropilin-1 by RNA-Interference and its Angiostatic Potential in the Treatment of Hepatocellular Carcinoma

(2010) E. Raskopf et al.   ZEITSCHRIFT FUR GASTROENTEROLOGIE

Guidance molecules in lung cancer

(2010) Patrick Nasarre et al.   Cell Adhesion & Migration

Neuropilin-1, as a New Therapeutic Target in Human Pancreatic Cancer

(2010) Akira Matsushita et al.   JOURNAL OF NIPPON MEDICAL SCHOOL

Advanced Glycation End Products Suppress Neuropilin-1 Expression in Podocytes by a Reduction in Sp1-Dependent Transcriptional Activity

(2009) Tzvetanka Bondeva et al.   AMERICAN JOURNAL OF NEPHROLOGY

Pulmonary Epithelial Neuropilin-1 Deletion Enhances Development of Cigarette Smoke–induced Emphysema

(2009) Anne Le et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Semaphorins and tumor angiogenesis

(2009) Guido Serini et al.   ANGIOGENESIS

Extracellular protein kinase CK2 is a novel associating protein of Neuropilin-1

(2009) Yasunori Shintani et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The role of neuropilins in cell signalling

(2009) Ian C. Zachary et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Neuropilin-2 expression in breast cancer: correlation with lymph node metastasis, poor prognosis, and regulation of CXCR4 expression

(2009) Hironao Yasuoka et al.   BMC CANCER

Angiogenesis is associated with the onset of hyperplasia in human ductal breast disease

(2009) J E Bluff et al.   BRITISH JOURNAL OF CANCER

Angiogenesis, vascular endothelial growth factor and its receptors in human surgical wounds

(2009) I. Kumar et al.   BRITISH JOURNAL OF SURGERY

Vascular Endothelial Growth Factor-C Protects Prostate Cancer Cells from Oxidative Stress by the Activation of Mammalian Target of Rapamycin Complex-2 and AKT-1

(2009) M. H. Muders et al.   CANCER RESEARCH

Neuropilins in Tumor Biology

(2009) A. Bagri et al.   CLINICAL CANCER RESEARCH

VEGFs and receptors involved in angiogenesis versus lymphangiogenesis

(2009) Marja Lohela et al.   CURRENT OPINION IN CELL BIOLOGY

Antivascular endothelial growth factor therapy for neovascular age-related macular degeneration

(2009) Thomas A Ciulla et al.   CURRENT OPINION IN OPHTHALMOLOGY

Semaphorin3a regulates endothelial cell number and podocyte differentiation during glomerular development

(2009) K. J. Reidy et al.   DEVELOPMENT

Neuropilin2 expressed in gastric cancer endothelial cells increases the proliferation and migration of endothelial cells in response to VEGF

(2009) Woo Ho Kim et al.   EXPERIMENTAL CELL RESEARCH

Mechanisms of the epithelial–mesenchymal transition by TGF-β

(2009) Michael K Wendt et al.   Future Oncology

Differential expression of the semaphorin 3A pathway in prostatic cancer

(2009) Mokrane Yacoub et al.   HISTOPATHOLOGY

Genome-based expression profiles as a single standardized microarray platform for the diagnosis of bladder pain syndrome/interstitial cystitis: an array of 139 genes model

(2009) Ling-Hong Tseng et al.   INTERNATIONAL UROGYNECOLOGY JOURNAL

The basics of epithelial-mesenchymal transition

(2009) Raghu Kalluri et al.   JOURNAL OF CLINICAL INVESTIGATION

Sonic hedgehog relates to colorectal carcinogenesis

(2009) Kozo Yoshikawa et al.   JOURNAL OF GASTROENTEROLOGY

Neuropilin-1 and neuropilin-2 are differentially expressed in human proteinuric nephropathies and cytokine-stimulated proximal tubular cells

(2009) Herbert Schramek et al.   LABORATORY INVESTIGATION

Altered expression of the SEMA3B gene in epithelial tumors

(2009) I. V. Pronina et al.   MOLECULAR BIOLOGY

The sonic hedgehog signaling pathway is reactivated in human renal cell carcinoma and plays orchestral role in tumor growth

(2009) Valérian Dormoy et al.   Molecular Cancer

Hearing Improvement after Bevacizumab in Patients with Neurofibromatosis Type 2

(2009) Scott R. Plotkin et al.   NEW ENGLAND JOURNAL OF MEDICINE

Alternate receptor usage of neuropilin-1 and glucose transporter protein 1 by the human T cell leukemia virus type 1

(2009) Qingwen Jin et al.   VIROLOGY

Neuropilin-1/GIPC1 Signaling Regulates α5β1 Integrin Traffic and Function in Endothelial Cells

(2009) Donatella Valdembri et al.   PLOS BIOLOGY

Neuropilins: structure, function and role in disease

(2008) Caroline Pellet-Many et al.   BIOCHEMICAL JOURNAL

Neuropilin-1 in regulation of VEGF-induced activation of p38MAPK and endothelial cell organization

(2008) H. Kawamura et al.   BLOOD

The assessment of angiogenesis and fibroblastic stromagenesis in hyperplastic and pre-invasive breast lesions

(2008) Kitty Pavlakis et al.   BMC CANCER

Decreased production of semaphorin 3A in the lesional skin of atopic dermatitis

(2008) M. Tominaga et al.   BRITISH JOURNAL OF DERMATOLOGY

Blocking Neuropilin-2 Function Inhibits Tumor Cell Metastasis

(2008) Maresa Caunt et al.   CANCER CELL

Neuropilin-1 Upholds Dedifferentiation and Propagation Phenotypes of Renal Cell Carcinoma Cells by Activating Akt and Sonic Hedgehog Axes

(2008) Ying Cao et al.   CANCER RESEARCH

Interleukin-8 increases vascular endothelial growth factor and neuropilin expression and stimulates ERK activation in human pancreatic cancer

(2008) Min Li et al.   CANCER SCIENCE

Tie2Cre-mediated inactivation of plexinD1 results in congenital heart, vascular and skeletal defects

(2008) Ying Zhang et al.   DEVELOPMENTAL BIOLOGY

Anti-inflammatory role of sympathetic nerves in chronic intestinal inflammation

(2008) R H Straub et al.   GUT

High levels of vascular endothelial growth factor and its receptors (VEGFR-1, VEGFR-2, neuropilin-1) are associated with worse outcome in breast cancer

(2008) Sriparna Ghosh et al.   HUMAN PATHOLOGY

Neuropilin-1 Expression on Regulatory T Cells Enhances Their Interactions with Dendritic Cells during Antigen Recognition

(2008) Milka Sarris et al.   IMMUNITY

Chromogranin A-, serotonin-, synaptophysin- and vascular endothelial growth factor-positive endocrine cells and the prognosis of colorectal cancer: An immunohistochemical and ultrastructural study

(2008) Maya Gulubova et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Semaphorin3A Alleviates Skin Lesions and Scratching Behavior in NC/Nga Mice, an Atopic Dermatitis Model

(2008) Junko Yamaguchi et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Neuropilin-1 is a receptor for transforming growth factor β-1, activates its latent form, and promotes regulatory T cell activity

(2008) Yelena Glinka et al.   JOURNAL OF LEUKOCYTE BIOLOGY

HIV-1 Upregulates VEGF in Podocytes

(2008) S. N. Korgaonkar et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Therapeutic Targeting of Neuropilin-2 on Colorectal Carcinoma Cells Implanted in the Murine Liver

(2008) M. J. Gray et al.   JNCI-Journal of the National Cancer Institute

Advanced glycation end-products suppress neuropilin-1 expression in podocytes

(2008) Tzvetanka Bondeva et al.   KIDNEY INTERNATIONAL

Semaphorin3a inhibits ureteric bud branching morphogenesis

(2008) Alda Tufro et al.   MECHANISMS OF DEVELOPMENT

Sorafenib in Advanced Hepatocellular Carcinoma

(2008) Josep M. Llovet et al.   NEW ENGLAND JOURNAL OF MEDICINE

Galectin-1, a novel ligand of neuropilin-1, activates VEGFR-2 signaling and modulates the migration of vascular endothelial cells

(2008) S H Hsieh et al.   ONCOGENE

Successful Inhibition of Tumor Development by Specific Class-3 Semaphorins Is Associated with Expression of Appropriate Semaphorin Receptors by Tumor Cells

(2008) Boaz Kigel et al.   PLoS One

Plexin B1 is downregulated in renal cell carcinomas and modulates cell growth

(2008) J. Javier Gómez Román et al.   Translational Research

Semaphorin signaling: progress made and promises ahead

(2008) Yeping Zhou et al.   TRENDS IN BIOCHEMICAL SCIENCES

Semaphorin3a disrupts podocyte foot processes causing acute proteinuria

(2007) R. Tapia et al.   KIDNEY INTERNATIONAL