PERK inhibits DNA replication during the Unfolded Protein Response via Claspin and Chk1

DNA damage control: regulation and functions of checkpoint kinase 1

(2015) Veronique A. J. Smits et al.   FEBS Journal

Tumor progression and the different faces of the PERK kinase

(2015) D Pytel et al.   ONCOGENE

Integrated stress response is critical for gemcitabine resistance in pancreatic ductal adenocarcinoma

(2015) L R Palam et al.   Cell Death & Disease

Druggable sensors of the unfolded protein response

(2014) Dustin J Maly et al.   Nature Chemical Biology

USP29 controls the stability of checkpoint adaptor Claspin by deubiquitination

(2014) Y Martín et al.   ONCOGENE

New histone supply regulates replication fork speed and PCNA unloading

(2013) Jakob Mejlvang et al.   JOURNAL OF CELL BIOLOGY

Replication Dynamics: Biases and Robustness of DNA Fiber Analysis

(2013) Hervé Técher et al.   JOURNAL OF MOLECULAR BIOLOGY

The impact of the unfolded protein response on human disease

(2012) Shiyu Wang et al.   JOURNAL OF CELL BIOLOGY

Analysis of DNA replication profiles in budding yeast and mammalian cells using DNA combing

(2012) Julien N. Bianco et al.   METHODS

UPR-Induced Resistance to Etoposide Is Downstream of PERK and Independent of Changes in Topoisomerase IIα Levels

(2012) Melissa J. Mann et al.   PLoS One

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Claspin and Chk1 regulate replication fork stability by different mechanisms

(2011) Jennifer Scorah et al.   CELL CYCLE

Anticancer therapy with checkpoint inhibitors: what, where and when?

(2011) Michelle D. Garrett et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Impaired tissue growth is mediated by checkpoint kinase 1 (CHK1) in the integrated stress response

(2010) E. Malzer et al.   JOURNAL OF CELL SCIENCE

A simple and optimized method of producing silanized surfaces for FISH and replication mapping on combed DNA fibers

(2008) Hélène Labit et al.   BIOTECHNIQUES

Claspin Promotes Normal Replication Fork Rates in Human Cells

(2008) Eva Petermann et al.   MOLECULAR BIOLOGY OF THE CELL