The focal adhesion-associated proteins DOCK5 and GIT2 comprise a rheostat in control of epithelial invasion

Insights into the biological functions of Dock family guanine nucleotide exchange factors

(2014) M. Laurin et al.   GENES & DEVELOPMENT

DOCK5 functions as a key signaling adaptor that links FcεRI signals to microtubule dynamics during mast cell degranulation

(2014) Kana Ogawa et al.   JOURNAL OF EXPERIMENTAL MEDICINE

DOCK2 and DOCK5 Act Additively in Neutrophils To Regulate Chemotaxis, Superoxide Production, and Extracellular Trap Formation

(2014) Mayuki Watanabe et al.   JOURNAL OF IMMUNOLOGY

Immune regulatory functions of DOCK family proteins in health and disease

(2013) Akihiko Nishikimi et al.   EXPERIMENTAL CELL RESEARCH

Phosphatidic Acid-dependent Recruitment and Function of the Rac Activator DOCK1 during Dorsal Ruffle Formation

(2013) Fumiyuki Sanematsu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rac-specific guanine nucleotide exchange factor DOCK1 is a critical regulator of HER2-mediated breast cancer metastasis

(2013) M. Laurin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Blockade of Inflammatory Responses by a Small-Molecule Inhibitor of the Rac Activator DOCK2

(2012) Akihiko Nishikimi et al.   CHEMISTRY & BIOLOGY

A βPIX-PAK2 Complex Confers Protection against Scrib-Dependent and Cadherin-Mediated Apoptosis

(2012) Scott R. Frank et al.   CURRENT BIOLOGY

Dimerization of DOCK2 Is Essential for DOCK2-Mediated Rac Activation and Lymphocyte Migration

(2012) Masao Terasawa et al.   PLoS One

Phosphorylation of dedicator of cytokinesis 1 (Dock180) at tyrosine residue Y722 by Src family kinases mediates EGFRvIII-driven glioblastoma tumorigenesis

(2012) H. Feng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Activation of Rac1 by Src-dependent phosphorylation of Dock180Y1811 mediates PDGFRα-stimulated glioma tumorigenesis in mice and humans

(2011) Haizhong Feng et al.   JOURNAL OF CLINICAL INVESTIGATION

Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation

(2011) Jean-Cheng Kuo et al.   NATURE CELL BIOLOGY

Rho protein crosstalk: another social network?

(2011) Christophe Guilluy et al.   TRENDS IN CELL BIOLOGY

Structural Basis of Membrane Targeting by the Dock180 Family of Rho Family Guanine Exchange Factors (Rho-GEFs)

(2010) Lakshmanane Premkumar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Rac1 exchange factor Dock5 is essential for bone resorption by osteoclasts

(2010) Virginie Vives et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Myosin II activity regulates vinculin recruitment to focal adhesions through FAK-mediated paxillin phosphorylation

(2010) Ana M. Pasapera et al.   JOURNAL OF CELL BIOLOGY

Regulation of thymocyte positive selection and motility by GIT2

(2010) Hyewon Phee et al.   NATURE IMMUNOLOGY

Paxillin-Kinase-Linker Tyrosine Phosphorylation Regulates Directional Cell Migration

(2009) Jianxin A. Yu et al.   MOLECULAR BIOLOGY OF THE CELL

Mechanically Activated Integrin Switch Controls  5 1 Function

(2009) J. C. Friedland et al.   SCIENCE

DOCK5 and DOCK1 Regulate Caco-2 Intestinal Epithelial Cell Spreading and Migration on Collagen IV

(2008) Matthew A. Sanders et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The atypical Rac activator Dock180 (Dock1) regulates myoblast fusion in vivo

(2008) M. Laurin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The PIX–GIT complex: A G protein signaling cassette in control of cell shape

(2008) Scott R. Frank et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY