Caspase-8 tyrosine-380 phosphorylation inhibits CD95 DISC function by preventing procaspase-8 maturation and cycling within the complex

Sequential Cdk1 and Plk1 phosphorylation of caspase-8 triggers apoptotic cell death during mitosis

(2014) Yves Matthess et al.   Molecular Oncology

Functions of caspase 8: The identified and the mysterious

(2014) Guy S. Salvesen et al.   SEMINARS IN IMMUNOLOGY

Lyn-mediated procaspase 8 dimerization blocks apoptotic signaling in B-cell chronic lymphocytic leukemia

(2013) F. Zonta et al.   BLOOD

Cancer-associated missense mutations of caspase-8 activate nuclear factor-κB signaling

(2013) Mizuo Ando et al.   CANCER SCIENCE

Regulation of the Src-PP2A Interaction in Tumor Necrosis Factor (TNF)-related Apoptosis-inducing Ligand (TRAIL)-induced Apoptosis

(2013) Jing Xu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Isolation, characterisation and reconstitution of cell death signalling complexes

(2013) Michelle A. Hughes et al.   METHODS

pERK 1/2 inhibit Caspase-8 induced apoptosis in cancer cells by phosphorylating it in a cell cycle specific manner

(2013) Ranadip Mandal et al.   Molecular Oncology

Cellular Mechanisms Controlling Caspase Activation and Function

(2013) A. B. Parrish et al.   Cold Spring Harbor Perspectives in Biology

The ‘complexities’ of life and death: Death receptor signalling platforms

(2012) Laura S. Dickens et al.   EXPERIMENTAL CELL RESEARCH

A Death Effector Domain Chain DISC Model Reveals a Crucial Role for Caspase-8 Chain Assembly in Mediating Apoptotic Cell Death

(2012) Laura S. Dickens et al.   MOLECULAR CELL

Stoichiometry of the CD95 Death-Inducing Signaling Complex: Experimental and Modeling Evidence for a Death Effector Domain Chain Model

(2012) Kolja Schleich et al.   MOLECULAR CELL

Targeting Src family kinases in anti-cancer therapies: turning promise into triumph

(2011) Siyuan Zhang et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Inducible Dimerization and Inducible Cleavage Reveal a Requirement for Both Processes in Caspase-8 Activation

(2010) Andrew Oberst et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Caspases and Kinases in a Death Grip

(2009) Manabu Kurokawa et al.   CELL

Studies of the molecular mechanism of caspase-8 activation by solution NMR

(2009) N Keller et al.   CELL DEATH AND DIFFERENTIATION

Reconstitution of the Death-Inducing Signaling Complex Reveals a Substrate Switch that Determines CD95-Mediated Death or Survival

(2009) Michelle A. Hughes et al.   MOLECULAR CELL

Structural and Biochemical Studies on Procaspase-8: New Insights on Initiator Caspase Activation

(2009) Nadine Keller et al.   STRUCTURE

Caspase-8: Fly or Die

(2008) S. M. Frisch   CANCER RESEARCH

Caspase 8 Promotes Peripheral Localization and Activation of Rab5

(2008) Vicente A. Torres et al.   JOURNAL OF BIOLOGICAL CHEMISTRY