Sensitive liquid chromatography mass spectrometry (LC-MS) assay reveals novel insights on DNA methylation and incorporation of gemcitabine, its metabolite difluorodeoxyuridine, deoxyuridine, and RX-3117 into DNA

Inhibition of thymidylate synthase by 2′,2′-difluoro-2′-deoxycytidine (Gemcitabine) and its metabolite 2′,2′-difluoro-2′-deoxyuridine

(2015) Richard J. Honeywell et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Cell Cycle Effects and Increased Adduct Formation by Temozolomide Enhance the Effect of Cytotoxic and Targeted Agents in Lung Cancer Cell Lines

(2014) A.D. Adema et al.   JOURNAL OF CHEMOTHERAPY

Novel Developments in the Use of Antimetabolites

(2014) Godefridus J. Peters   NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS

Metabolism, mechanism of action and sensitivity profile of fluorocyclopentenylcytosine (RX-3117; TV-1360)

(2013) Godefridus J. Peters et al.   INVESTIGATIONAL NEW DRUGS

Determination of the Phosphorylated Metabolites of Gemcitabine and of Difluorodeoxyuridine by LCMSMS

(2011) Richard J. Honeywell et al.   NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS

Cyclopentenyl cytosine increases gemcitabine radiosensitisation in human pancreatic cancer cells

(2008) C van Bree et al.   BRITISH JOURNAL OF CANCER