Suppression of gyrase-mediated resistance by C7 aryl fluoroquinolones
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Title
Suppression of gyrase-mediated resistance by C7 aryl fluoroquinolones
Authors
Keywords
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Journal
NUCLEIC ACIDS RESEARCH
Volume 44, Issue 7, Pages 3304-3316
Publisher
Oxford University Press (OUP)
Online
2016-03-17
DOI
10.1093/nar/gkw161
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- Topoisomerase IV-quinolone interactions are mediated through a water-metal ion bridge: mechanistic basis of quinolone resistance
- (2013) Katie J. Aldred et al. NUCLEIC ACIDS RESEARCH
- Resistance surveillance studies: a multifaceted problem—the fluoroquinolone example
- (2012) A. Dalhoff INFECTION
- Effect of Ciprofloxacin Concentration on the Frequency and Nature of Resistant Mutants Selected fromPseudomonas aeruginosa mutSandmutTHypermutators
- (2011) Natalia R. Morero et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Fluoroquinolone and Quinazolinedione Activities against Wild-Type and Gyrase Mutant Strains of Mycobacterium smegmatis
- (2011) Muhammad Malik et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
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