Translocation and deletion breakpoints in cancer genomes are associated with potential non-B DNA-forming sequences

Ligase I and ligase III mediate the DNA double-strand break ligation in alternative end-joining

(2016) Guangqing Lu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Repair Pathway Choices and Consequences at the Double-Strand Break

(2016) Raphael Ceccaldi et al.   TRENDS IN CELL BIOLOGY

DNA Triplet Repeat Expansion and Mismatch Repair

(2015) Ravi R. Iyer et al.   Annual Review of Biochemistry

DNA Secondary Structure at Chromosomal Fragile Sites in Human Disease

(2015) Ryan G. Thys et al.   CURRENT GENOMICS

Snaps and mends: DNA breaks and chromosomal translocations

(2015) Saniya M. Javadekar et al.   FEBS Journal

Histone modifications predispose genome regions to breakage and translocation

(2015) Bharat Burman et al.   GENES & DEVELOPMENT

A Role for Non-B DNA Forming Sequences in Mediating Microlesions Causing Human Inherited Disease

(2015) Mihir Anant Kamat et al.   HUMAN MUTATION

Evidence for chromosome fragility at the frataxin locus in Friedreich ataxia

(2015) Daman Kumari et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Local DNA dynamics shape mutational patterns of mononucleotide repeats in human genomes

(2015) Albino Bacolla et al.   NUCLEIC ACIDS RESEARCH

LINE-1 expression and retrotransposition in Barrett’s esophagus and esophageal carcinoma

(2015) Tara T. Doucet-O'Hare et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Microhomology-Mediated End Joining: A Back-up Survival Mechanism or Dedicated Pathway?

(2015) Agnel Sfeir et al.   TRENDS IN BIOCHEMICAL SCIENCES

Mutagenic consequences of a single G-quadruplex demonstrate mitotic inheritance of DNA replication fork barriers

(2015) Bennie Lemmens et al.   Nature Communications

Short Inverted Repeats Are Hotspots for Genetic Instability: Relevance to Cancer Genomes

(2015) Steve Lu et al.   Cell Reports

Frequent L1 retrotranspositions originating from TTC28 in colorectal cancer

(2015) Esa Pitkänen et al.   Oncotarget

Updating the mechanisms of common fragile site instability: how to reconcile the different views?

(2014) Benoît Le Tallec et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The contribution of co-transcriptional RNA:DNA hybrid structures to DNA damage and genome instability

(2014) Stephan Hamperl et al.   DNA REPAIR

DNA double-strand break repair pathway choice and cancer

(2014) Tomas Aparicio et al.   DNA REPAIR

Impact of alternative DNA structures on DNA damage, DNA repair, and genetic instability

(2014) Guliang Wang et al.   DNA REPAIR

Palindrome-Mediated and Replication-Dependent Pathogenic Structural Rearrangements within theNF1Gene

(2014) Meng-Chang Hsiao et al.   HUMAN MUTATION

Chromosomal Translocations in Human Cells Are Generated by Canonical Nonhomologous End-Joining

(2014) Hind Ghezraoui et al.   MOLECULAR CELL

COSMIC: exploring the world's knowledge of somatic mutations in human cancer

(2014) Simon A. Forbes et al.   NUCLEIC ACIDS RESEARCH

Extensive transduction of nonrepetitive DNA mediated by L1 retrotransposition in cancer genomes

(2014) J. M. C. Tubio et al.   SCIENCE

Mechanisms of genome instability induced by RNA-processing defects

(2014) Yujia A. Chan et al.   TRENDS IN GENETICS

Analysis of the t(3;8) of hereditary renal cell carcinoma: a palindrome-mediated translocation

(2014) Takema Kato et al.   Cancer Genetics

Breakpoint analysis of the recurrent constitutional t(8;22)(q24.13;q11.21) translocation

(2014) Divya Mishra et al.   Molecular Cytogenetics

Topoisomerase I Plays a Critical Role in Suppressing Genome Instability at a Highly Transcribed G-Quadruplex-Forming Sequence

(2014) Puja Yadav et al.   PLoS Genetics

DNA A-tracts Are Not Curved in Solutions Containing High Concentrations of Monovalent Cations

(2013) Earle Stellwagen et al.   BIOCHEMISTRY

Identification of Early Replicating Fragile Sites that Contribute to Genome Instability

(2013) Jacqueline H. Barlow et al.   CELL

Molecular Pathways: Transcription Factories and Chromosomal Translocations

(2013) C. S. Osborne   CLINICAL CANCER RESEARCH

The cellular etiology of chromosome translocations

(2013) Vassilis Roukos et al.   CURRENT OPINION IN CELL BIOLOGY

A survey of intragenic breakpoints in glioblastoma identifies a distinct subset associated with poor survival

(2013) S. Zheng et al.   GENES & DEVELOPMENT

Enhancement of microhomology-mediated genomic rearrangements by transient loss of mouse Bloom syndrome helicase

(2013) A. Yamanishi et al.   GENOME RESEARCH

Role of DNA secondary structures in fragile site breakage along human chromosome 10

(2013) Laura W. Dillon et al.   HUMAN MOLECULAR GENETICS

Coordinated Actions of SLX1-SLX4 and MUS81-EME1 for Holliday Junction Resolution in Human Cells

(2013) Haley D.M. Wyatt et al.   MOLECULAR CELL

DNA Repair Mechanisms in Huntington’s Disease

(2013) Ida Jonson et al.   MOLECULAR NEUROBIOLOGY

An Exposure to the Oxidized DNA Enhances Both Instability of Genome and Survival in Cancer Cells

(2013) Svetlana V. Kostyuk et al.   PLoS One

Genomic Instability in Cancer

(2013) T. Abbas et al.   Cold Spring Harbor Perspectives in Biology

Two sequential cleavage reactions on cruciform DNA structures cause palindrome-mediated chromosomal translocations

(2013) Hidehito Inagaki et al.   Nature Communications

Abnormal Base Excision Repair at Trinucleotide Repeats Associated with Diseases: A Tissue-Selective Mechanism

(2013) Agathi-Vasiliki Goula et al.   Genes

A non-B DNA can replace heptamer of V(D)J recombination when present along with a nonamer: implications in chromosomal translocations and cancer

(2012) Mayilaadumveettil Nishana et al.   BIOCHEMICAL JOURNAL

A Distinct Replication Fork Protection Pathway Connects Fanconi Anemia Tumor Suppressors to RAD51-BRCA1/2

(2012) Katharina Schlacher et al.   CANCER CELL

Spatial Organization of the Mouse Genome and Its Role in Recurrent Chromosomal Translocations

(2012) Yu Zhang et al.   CELL

Chromosomal translocations and palindromic AT-rich repeats

(2012) Takema Kato et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

A genome-wide analysis of common fragile sites: What features determine chromosomal instability in the human genome?

(2012) Arkarachai Fungtammasan et al.   GENOME RESEARCH

Somatic rearrangements across cancer reveal classes of samples with distinct patterns of DNA breakage and rearrangement-induced hypermutability

(2012) Y. Drier et al.   GENOME RESEARCH

Potential G-quadruplex formation at breakpoint regions of chromosomal translocations in cancer may explain their fragility

(2012) Vijeth K. Katapadi et al.   GENOMICS

Molecular Dynamics Study of the Role of the Spine of Hydration in DNA A-Tracts in Determining Nucleosome Occupancy

(2012) Xiao Zhu et al.   JOURNAL OF PHYSICAL CHEMISTRY B

NMR Study on the B–Z Junction Formation of DNA Duplexes Induced by Z-DNA Binding Domain of Human ADAR1

(2012) Yeon-Mi Lee et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Triplex DNA-binding proteins are associated with clinical outcomes revealed by proteomic measurements in patients with colorectal cancer

(2012) Laura D Nelson et al.   Molecular Cancer

Genome-wide Screen Identifies Pathways that Govern GAA/TTC Repeat Fragility and Expansions in Dividing and Nondividing Yeast Cells

(2012) Yu Zhang et al.   MOLECULAR CELL

Recombination-restarted replication makes inverted chromosome fusions at inverted repeats

(2012) Ken’Ichi Mizuno et al.   NATURE

Sequence analysis of mutations and translocations across breast cancer subtypes

(2012) Shantanu Banerji et al.   NATURE

Comprehensive molecular characterization of human colon and rectal cancer

(2012)   NATURE

Non-B DB v2.0: a database of predicted non-B DNA-forming motifs and its associated tools

(2012) Regina Z. Cer et al.   NUCLEIC ACIDS RESEARCH

Oncogenes in Cell Survival and Cell Death

(2012) J. Shortt et al.   Cold Spring Harbor Perspectives in Biology

Double-Strand Break Repair-Independent Role for BRCA2 in Blocking Stalled Replication Fork Degradation by MRE11

(2011) Katharina Schlacher et al.   CELL

Transcription-induced DNA toxicity at trinucleotide repeats

(2011) Yunfu Lin et al.   CELL CYCLE

RAF gene fusion breakpoints in pediatric brain tumors are characterized by significant enrichment of sequence microhomology

(2011) A. R. J. Lawson et al.   GENOME RESEARCH

New insights into repeat instability

(2011) Elizabeth I. McIvor et al.   RNA Biology

Non random distribution of genomic features in breakpoint regions involved in chronic myeloid leukemia cases with variant t(9;22) or additional chromosomal rearrangements

(2010) Francesco Albano et al.   Molecular Cancer

Signatures of mutation and selection in the cancer genome

(2010) Graham R. Bignell et al.   NATURE

Formation of a G-quadruplex at the BCL2 major breakpoint region of the t(14;18) translocation in follicular lymphoma

(2010) Mridula Nambiar et al.   NUCLEIC ACIDS RESEARCH

Crystal structure of a junction between two Z-DNA helices

(2010) M. de Rosa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Over half of breakpoints in gene pairs involved in cancer-specific recurrent translocations are mapped to human chromosomal fragile sites

(2009) Allison A Burrow et al.   BMC GENOMICS

Non-B DNA structure-induced genetic instability and evolution

(2009) Junhua Zhao et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Structure-Specific Recognition of Friedreich's Ataxia (GAA)nRepeats by Benzoquinoquinoxaline Derivatives

(2009) Helen Bergquist et al.   CHEMBIOCHEM

Different molecular mechanisms causing 9p21 deletions in acute lymphoblastic leukemia of childhood

(2009) Francesca Novara et al.   HUMAN GENETICS

Direct Observation of the Hole Protonation State and Hole Localization Site in DNA-Oligomers

(2009) Amitava Adhikary et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The tumor suppressor gene TRC8/RNF139 is disrupted by a constitutional balanced translocation t(8;22)(q24.13;q11.21) in a young girl with dysgerminoma

(2009) Stefania Gimelli et al.   Molecular Cancer

Intrinsic flexibility of B-DNA: the experimental TRX scale

(2009) Brahim Heddi et al.   NUCLEIC ACIDS RESEARCH

The unique structure of A-tracts and intrinsic DNA bending

(2009) Tali E. Haran et al.   QUARTERLY REVIEWS OF BIOPHYSICS

The Hypocrea jecorina (Trichoderma reesei) hypercellulolytic mutant RUT C30 lacks a 85 kb (29 gene-encoding) region of the wild-type genome

(2008) Verena Seidl et al.   BMC GENOMICS

Human Chromosomal Translocations at CpG Sites and a Theoretical Basis for Their Lineage and Stage Specificity

(2008) Albert G. Tsai et al.   CELL

Abundance and length of simple repeats in vertebrate genomes are determined by their structural properties

(2008) A. Bacolla et al.   GENOME RESEARCH

Oxidation of Guanine in G, GG, and GGG Sequence Contexts by Aromatic Pyrenyl Radical Cations and Carbonate Radical Anions:  Relationship between Kinetics and Distribution of Alkali-Labile Lesions

(2008) Young Ae Lee et al.   JOURNAL OF PHYSICAL CHEMISTRY B

DNA Structure-induced Genomic Instability In Vivo

(2008) Guliang Wang et al.   JNCI-Journal of the National Cancer Institute

Towards a molecular dynamics consensus view of B-DNA flexibility

(2008) Alberto Pérez et al.   NUCLEIC ACIDS RESEARCH

Characteristic sequence motifs located at the genomic breakpoints of the translocation t(12;16) and t(12;22) in myxoid liposarcoma

(2008) Hua Xiang et al.   PATHOLOGY