Overlapping roles for PARP1 and PARP2 in the recruitment of endogenous XRCC1 and PNKP into oxidized chromatin

PARP3 is a sensor of nicked nucleosomes and monoribosylates histone H2BGlu2

(2016) Gabrielle J. Grundy et al.   Nature Communications

Mutations in PNKP Cause Recessive Ataxia with Oculomotor Apraxia Type 4

(2015) Jose Bras et al.   AMERICAN JOURNAL OF HUMAN GENETICS

The XRCC1 phosphate-binding pocket binds poly (ADP-ribose) and is required for XRCC1 function

(2015) Claire Breslin et al.   NUCLEIC ACIDS RESEARCH

Protein ADP-ribosylation and the cellular response to DNA strand breaks

(2014) K.W. Caldecott   DNA REPAIR

DNA single-strand break repair

(2014) Keith W. Caldecott   EXPERIMENTAL CELL RESEARCH

Improving CRISPR-Cas nuclease specificity using truncated guide RNAs

(2014) Yanfang Fu et al.   NATURE BIOTECHNOLOGY

DNA ligase III acts as a DNA strand break sensor in the cellular orchestration of DNA strand break repair

(2014) Ismail Abdou et al.   NUCLEIC ACIDS RESEARCH

PARP3 affects the relative contribution of homologous recombination and nonhomologous end-joining pathways

(2014) Carole Beck et al.   NUCLEIC ACIDS RESEARCH

PARP-2 and PARP-3 are selectively activated by 5′ phosphorylated DNA breaks through an allosteric regulatory mechanism shared with PARP-1

(2014) Marie-France Langelier et al.   NUCLEIC ACIDS RESEARCH

Emerging Roles of the Nucleolus in Regulating the DNA Damage Response: The Noncanonical DNA Repair Enzyme APE1/Ref-1 as a Paradigmatical Example

(2013) Giulia Antoniali et al.   ANTIOXIDANTS & REDOX SIGNALING

The FHA and BRCT domains recognize ADP-ribosylation during DNA damage response

(2013) M. Li et al.   GENES & DEVELOPMENT

Progressive cerebellar atrophy and polyneuropathy: expanding the spectrum of PNKP mutations

(2012) Cathryn Poulton et al.   NEUROGENETICS

XRCC1 coordinates disparate responses and multiprotein repair complexes depending on the nature and context of the DNA damage

(2011) Audun Hanssen-Bauer et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

PARP-3 and APLF Function Together to Accelerate Nonhomologous End-Joining

(2011) Stuart L. Rulten et al.   MOLECULAR CELL

Poly(ADP-ribose) polymerase 3 (PARP3), a newcomer in cellular response to DNA damage and mitotic progression

(2011) C. Boehler et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mutations in PNKP cause microcephaly, seizures and defects in DNA repair

(2010) Jun Shen et al.   NATURE GENETICS

Delocalization of nucleolar poly(ADP-ribose) polymerase-1 to the nucleoplasm and its novel link to cellular sensitivity to DNA damage

(2009) Ann Rancourt et al.   DNA REPAIR

DNA 3'-Phosphatase Activity Is Critical for Rapid Global Rates of Single-Strand Break Repair following Oxidative Stress

(2009) C. Breslin et al.   MOLECULAR AND CELLULAR BIOLOGY

APLF (C2orf13) Is a Novel Component of Poly(ADP-Ribose) Signaling in Mammalian Cells

(2008) S. L. Rulten et al.   MOLECULAR AND CELLULAR BIOLOGY

Single-strand break repair and genetic disease

(2008) Keith W. Caldecott   NATURE REVIEWS GENETICS