Mechanism of endonuclease cleavage by the HigB toxin

The toxin GraT inhibits ribosome biogenesis

(2016) Andres Ainelo et al.   MOLECULAR MICROBIOLOGY

Transition State Charge Stabilization and Acid–Base Catalysis of mRNA Cleavage by the Endoribonuclease RelE

(2015) Brian F. Dunican et al.   BIOCHEMISTRY

Cut to the chase–Regulating translation through RNA cleavage

(2015) Nicholas Sofos et al.   BIOCHIMIE

Molecular basis of ribosome recognition and mRNA hydrolysis by theE. coliYafQ toxin

(2015) Tatsuya Maehigashi et al.   NUCLEIC ACIDS RESEARCH

Defining the mRNA recognition signature of a bacterial toxin protein

(2015) Marc A. Schureck et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Stochastic induction of persister cells by HipA through (p)ppGpp-mediated activation of mRNA endonucleases

(2015) Elsa Germain et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Growth-regulating Mycobacterium tuberculosis VapC-mt4 toxin is an isoacceptor-specific tRNase

(2015) Jonathan W. Cruz et al.   Nature Communications

Molecular Mechanisms Underlying Bacterial Persisters

(2014) Etienne Maisonneuve et al.   CELL

Toxin YafQ increases persister cell formation by reducing indole signalling

(2014) Ying Hu et al.   ENVIRONMENTAL MICROBIOLOGY

Structural and Functional Characterization ofEscherichia coliToxin-Antitoxin Complex DinJ-YafQ

(2014) Yajing Liang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanisms of Toxin Inhibition and Transcriptional Repression byEscherichia coliDinJ-YafQ

(2014) Ajchareeya Ruangprasert et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Doc Toxin Is a Kinase That Inactivates Elongation Factor Tu

(2014) Jonathan W. Cruz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Internalization of Salmonella by Macrophages Induces Formation of Nonreplicating Persisters

(2014) S. Helaine et al.   SCIENCE

An RNA-seq method for defining endoribonuclease cleavage specificity identifies dual rRNA substrates for toxin MazF-mt3

(2014) Jason M. Schifano et al.   Nature Communications

Bacterial Toxin RelE: A Highly Efficient Ribonuclease with Exquisite Substrate Specificity Using Atypical Catalytic Residues

(2013) Meghan A. Griffin et al.   BIOCHEMISTRY

Uncovering the Determinants of a Highly Perturbed Tyrosine pKa in the Active Site of Ketosteroid Isomerase

(2013) Jason P. Schwans et al.   BIOCHEMISTRY

RETRACTED: (p)ppGpp Controls Bacterial Persistence by Stochastic Induction of Toxin-Antitoxin Activity

(2013) Etienne Maisonneuve et al.   CELL

Structure of theProteus vulgarisHigB-(HigA)2-HigB Toxin-Antitoxin Complex

(2013) Marc A. Schureck et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular Mechanism of Bacterial Persistence by HipA

(2013) Elsa Germain et al.   MOLECULAR CELL

The Fic protein Doc uses an inverted substrate to phosphorylate and inactivate EF-Tu

(2013) Daniel Castro-Roa et al.   Nature Chemical Biology

YoeB–ribosome structure: a canonical RNase that requires the ribosome for its specific activity

(2013) Shu Feng et al.   NUCLEIC ACIDS RESEARCH

Mycobacterial toxin MazF-mt6 inhibits translation through cleavage of 23S rRNA at the ribosomal A site

(2013) J. M. Schifano et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

VapC20 of Mycobacterium tuberculosis cleaves the Sarcin–Ricin loop of 23S rRNA

(2013) Kristoffer S. Winther et al.   Nature Communications

Quantitative, directional measurement of electric field heterogeneity in the active site of ketosteroid isomerase

(2012) A. T. Fafarman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Decoding in the Absence of a Codon by tmRNA and SmpB in the Ribosome

(2012) C. Neubauer et al.   SCIENCE

Toxin-Antitoxin Systems in Bacteria and Archaea

(2011) Yoshihiro Yamaguchi et al.   Annual Review of Genetics

Bacterial Toxin RelE Mediates Frequent Codon-independent mRNA Cleavage from the 5′ End of Coding Regionsin Vivo

(2011) Jennifer M. Hurley et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Enteric virulence associated protein VapC inhibits translation by cleavage of initiator tRNA

(2011) K. S. Winther et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bacterial persistence by RNA endonucleases

(2011) Etienne Maisonneuve et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Novel Mechanism of Programmed Cell Death in Bacteria by Toxin–Antitoxin Systems Corrupts Peptidoglycan Synthesis

(2011) Hannes Mutschler et al.   PLOS BIOLOGY

XDS

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

YeeV is an Escherichia coli toxin that inhibits cell division by targeting the cytoskeleton proteins, FtsZ and MreB

(2010) Qian Tan et al.   MOLECULAR MICROBIOLOGY

RatA (YfjG), an Escherichia coli toxin, inhibits 70S ribosome association to block translation initiation

(2010) Yonglong Zhang et al.   MOLECULAR MICROBIOLOGY

Dissection of the structural and functional role of a conserved hydration site in RNase T1

(2010) Ulrike Langhorst et al.   PROTEIN SCIENCE

The Structural Basis for mRNA Recognition and Cleavage by the Ribosome-Dependent Endonuclease RelE

(2009) Cajetan Neubauer et al.   CELL

Structure of RNase Sa2 complexes with mononucleotides - new aspects of catalytic reaction and substrate recognition

(2009) Vladena Bauerová-Hlinková et al.   FEBS Journal

Inhibitory Mechanism ofEscherichia coliRelE-RelB Toxin-Antitoxin Module Involves a Helix Displacement Near an mRNA Interferase Active Site

(2009) Guang-Yao Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bacterial Toxin HigB Associates with Ribosomes and Mediates Translation-dependent mRNA Cleavage at A-rich Sites

(2009) Jennifer M. Hurley et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Control of translation initiation involves a factor-induced rearrangement of helix 44 of 16S ribosomal RNA

(2009) Daoming Qin et al.   MOLECULAR MICROBIOLOGY

Catalytic Strategies of Self-Cleaving Ribozymes

(2008) Jesse C. Cochrane et al.   ACCOUNTS OF CHEMICAL RESEARCH