Enrichment of Cdk1-cyclins at DNA double-strand breaks stimulates Fun30 phosphorylation and DNA end resection

The Fun30 Chromatin Remodeler Fft3 Controls Nuclear Organization and Chromatin Structure of Insulators and Subtelomeres in Fission Yeast

(2015) Babett Steglich et al.   PLoS Genetics

DNA double-strand break repair pathway choice and cancer

(2014) Tomas Aparicio et al.   DNA REPAIR

Phosphorylation of EXO1 by CDKs 1 and 2 regulates DNA end resection and repair pathway choice

(2014) Nozomi Tomimatsu et al.   Nature Communications

Premature Cdk1/Cdc5/Mus81 pathway activation induces aberrant replication and deleterious crossover

(2013) Barnabas Szakal et al.   EMBO JOURNAL

Mec1/ATR regulates the generation of single-stranded DNA that attenuates Tel1/ATM signaling at DNA ends

(2013) Michela Clerici et al.   EMBO JOURNAL

Double-strand break repair: 53BP1 comes into focus

(2013) Stephanie Panier et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Regulation of Mus81–Eme1 Holliday junction resolvase in response to DNA damage

(2013) Pierre-Marie Dehé et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Cks confers specificity to phosphorylation-dependent CDK signaling pathways

(2013) Denise A McGrath et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Multisite phosphorylation networks as signal processors for Cdk1

(2013) Mardo Kõivomägi et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Temporal regulation of the Mus81-Mms4 endonuclease ensures cell survival under conditions of DNA damage

(2013) Irene Saugar et al.   NUCLEIC ACIDS RESEARCH

Site-Specific Phosphorylation of the DNA Damage Response Mediator Rad9 by Cyclin-Dependent Kinases Regulates Activation of Checkpoint Kinase 1

(2013) Carla Manuela Abreu et al.   PLoS Genetics

Multiple phosphorylation of Rad9 by CDK is required for DNA damage checkpoint activation

(2012) Guoliang Wang et al.   CELL CYCLE

CDK targeting of NBS1 promotes DNA-end resection, replication restart and homologous recombination

(2012) Jacob Falck et al.   EMBO REPORTS

The Saccharomyces cerevisiae Chromatin Remodeler Fun30 Regulates DNA End Resection and Checkpoint Deactivation

(2012) V. V. Eapen et al.   MOLECULAR AND CELLULAR BIOLOGY

The yeast Fun30 and human SMARCAD1 chromatin remodellers promote DNA end resection

(2012) Thomas Costelloe et al.   NATURE

The Fun30 nucleosome remodeller promotes resection of DNA double-strand break ends

(2012) Xuefeng Chen et al.   NATURE

Mre11 regulates CtIP-dependent double-strand break repair by interaction with CDK2

(2012) Jeffrey Buis et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Cell cycle-dependent regulation of the nuclease activity of Mus81–Eme1/Mms4

(2012) María Gallo-Fernández et al.   NUCLEIC ACIDS RESEARCH

Chemical Genetics Reveals a Specific Requirement for Cdk2 Activity in the DNA Damage Response and Identifies Nbs1 as a Cdk2 Substrate in Human Cells

(2012) Lara Wohlbold et al.   PLoS Genetics

SWI/SNF-Like Chromatin Remodeling Factor Fun30 Supports Point Centromere Function in S. cerevisiae

(2012) Mickaël Durand-Dubief et al.   PLoS Genetics

Dpb11 coordinates Mec1 kinase activation with cell cycle-regulated Rad9 recruitment

(2011) Boris Pfander et al.   EMBO JOURNAL

Roles of Chromatin Remodeling Factors in the Formation and Maintenance of Heterochromatin Structure

(2011) Qun Yu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cdk1 uncouples CtIP-dependent resection and Rad51 filament formation during M-phase double-strand break repair

(2011) Shaun E. Peterson et al.   JOURNAL OF CELL BIOLOGY

Maintenance of Silent Chromatin through Replication Requires SWI/SNF-like Chromatin Remodeler SMARCAD1

(2011) Samuel P. Rowbotham et al.   MOLECULAR CELL

Dynamics of Cdk1 Substrate Specificity during the Cell Cycle

(2011) Mardo Kõivomägi et al.   MOLECULAR CELL

A function for cyclin D1 in DNA repair uncovered by protein interactome analyses in human cancers

(2011) Siwanon Jirawatnotai et al.   NATURE

Cell cycle regulation of DNA double-strand break end resection by Cdk1-dependent Dna2 phosphorylation

(2011) Xuefeng Chen et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Distinct Cdk1 Requirements during Single-Strand Annealing, Noncrossover, and Crossover Recombination

(2011) Camilla Trovesi et al.   PLoS Genetics

The FUN30 Chromatin Remodeler, Fft3, Protects Centromeric and Subtelomeric Domains from Euchromatin Formation

(2011) Annelie Strålfors et al.   PLoS Genetics

Temporally and Biochemically Distinct Activities of Exo1 during Meiosis: Double-Strand Break Resection and Resolution of Double Holliday Junctions

(2010) Kseniya Zakharyevich et al.   MOLECULAR CELL

Mechanism of the ATP-dependent DNA end-resection machinery from Saccharomyces cerevisiae

(2010) Hengyao Niu et al.   NATURE

DNA end resection by Dna2–Sgs1–RPA and its stimulation by Top3–Rmi1 and Mre11–Rad50–Xrs2

(2010) Petr Cejka et al.   NATURE

Mre11–Rad50–Xrs2 and Sae2 promote 5′ strand resection of DNA double-strand breaks

(2010) Matthew L Nicolette et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A truncated DNA-damage-signaling response is activated after DSB formation in the G1 phase of Saccharomyces cerevisiae

(2010) Ryan Janke et al.   NUCLEIC ACIDS RESEARCH

An overview of Cdk1-controlled targets and processes

(2010) Jorrit M Enserink et al.   Cell Division

Dynamics of Rad9 Chromatin Binding and Checkpoint Function Are Mediated by Its Dimerization and Are Cell Cycle–Regulated by CDK1 Activity

(2010) Magda Granata et al.   PLoS Genetics

Defective Resection at DNA Double-Strand Breaks Leads to De Novo Telomere Formation and Enhances Gene Targeting

(2010) Woo-Hyun Chung et al.   PLoS Genetics

Cdk1 Targets Srs2 to Complete Synthesis-Dependent Strand Annealing and to Promote Recombinational Repair

(2010) Marco Saponaro et al.   PLoS Genetics

Human CtIP Mediates Cell Cycle Control of DNA End Resection and Double Strand Break Repair

(2009) Pablo Huertas et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cdc28/Cdk1 positively and negatively affects genome stability inS. cerevisiae

(2009) Jorrit M. Enserink et al.   JOURNAL OF CELL BIOLOGY

The SNF2-Family Member Fun30 Promotes Gene Silencing in Heterochromatic Loci

(2009) Ana Neves-Costa et al.   PLoS One

Systematic identification of cell cycle-dependent yeast nucleocytoplasmic shuttling proteins by prediction of composite motifs

(2009) S. Kosugi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Global Analysis of Cdk1 Substrate Phosphorylation Sites Provides Insights into Evolution

(2009) L. J. Holt et al.   SCIENCE

Sgs1 Helicase and Two Nucleases Dna2 and Exo1 Resect DNA Double-Strand Break Ends

(2008) Zhu Zhu et al.   CELL

Histone methyltransferase Dot1 and Rad9 inhibit single-stranded DNA accumulation at DSBs and uncapped telomeres

(2008) Federico Lazzaro et al.   EMBO JOURNAL

Differential Regulation of the Cellular Response to DNA Double-Strand Breaks in G1

(2008) Jacqueline H. Barlow et al.   MOLECULAR CELL

Colocalization of Sensors Is Sufficient to Activate the DNA Damage Checkpoint in the Absence of Damage

(2008) Carla Yaneth Bonilla et al.   MOLECULAR CELL

Sae2, Exo1 and Sgs1 collaborate in DNA double-strand break processing

(2008) Eleni P. Mimitou et al.   NATURE

CDK targets Sae2 to control DNA-end resection and homologous recombination

(2008) Pablo Huertas et al.   NATURE