Structural basis for PHDVC5HCHNSD1–C2HRNizp1interaction: implications for Sotos syndrome

The NSD family of protein methyltransferases in human cancer

(2015) Theodore Vougiouklakis et al.   Epigenomics

The NSD 1 and EZH 2 Overgrowth Genes, Similarities and Differences

(2013) KATRINA TATTON-BROWN et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART C-SEMINARS IN MEDICAL GENETICS

Readout of Epigenetic Modifications

(2013) Dinshaw J. Patel et al.   Annual Review of Biochemistry

Diverse functions of PHD fingers of the MLL/KMT2 subfamily

(2013) Muzaffar Ali et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Structure of human Sp140 PHD finger: an atypical fold interacting with Pin1

(2013) Chiara Zucchelli et al.   FEBS Journal

The double PHD finger domain of MOZ/MYST3 induces  -helical structure of the histone H3 tail to facilitate acetylation and methylation sampling and modification

(2013) I. Dreveny et al.   NUCLEIC ACIDS RESEARCH

Combinatorial readout of unmodified H3R2 and acetylated H3K14 by the tandem PHD finger of MOZ reveals a regulatory mechanism for HOXA9 transcription

(2012) Y. Qiu et al.   GENES & DEVELOPMENT

The Methyltransferase NSD3 Has Chromatin-binding Motifs, PHD5-C5HCH, That Are Distinct from Other NSD (Nuclear Receptor SET Domain) Family Members in Their Histone H3 Recognition

(2012) Chao He et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CING: an integrated residue-based structure validation program suite

(2012) Jurgen F. Doreleijers et al.   JOURNAL OF BIOMOLECULAR NMR

Analysis of NUP98/NSD1 translocations in adult AML and MDS patients

(2012) F Thol et al.   LEUKEMIA

Understanding the language of Lys36 methylation at histone H3

(2012) Eric J. Wagner et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Perceiving the epigenetic landscape through histone readers

(2012) Catherine A Musselman et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

AIRE-PHD fingers are structural hubs to maintain the integrity of chromatin-associated interactome

(2012) Massimiliano Gaetani et al.   NUCLEIC ACIDS RESEARCH

Exploring PHD Fingers and H3K4me0 Interactions with Molecular Dynamics Simulations and Binding Free Energy Calculations: AIRE-PHD1, a Comparative Study

(2012) Dimitrios Spiliotopoulos et al.   PLoS One

Reversed clinical phenotype due to a microduplication of Sotos syndrome region detected by array CGH: Microcephaly, developmental delay and delayed bone age

(2011) Han Zhang et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Structural insights into the regulation and the recognition of histone marks by the SET domain of NSD1

(2011) Masayo Morishita et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

NUP98/NSD1 characterizes a novel poor prognostic group in acute myeloid leukemia with a distinct HOX gene expression pattern

(2011) I. H. I. M. Hollink et al.   BLOOD

The Structure of NSD1 Reveals an Autoregulatory Mechanism Underlying Histone H3K36 Methylation

(2011) Qi Qiao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Analyzing protein–protein interactions by quantitative mass spectrometry

(2011) Florian E. Paul et al.   METHODS

Protein-protein interactions: Analysis of a false positive GST pulldown result

(2011) Sandra Wissmueller et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

The NIZP1 KRAB and C2HR domains cross-talk for transcriptional regulation

(2010) Regine Losson et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Pro Isomerization in MLL1 PHD3-Bromo Cassette Connects H3K4me Readout to CyP33 and HDAC-Mediated Repression

(2010) Zhanxin Wang et al.   CELL

Keeping it in the family: diverse histone recognition by conserved structural folds

(2010) Kyoko L. Yap et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

NSD1 PHD domains bind methylated H3K4 and H3K9 using interactions disrupted by point mutations in human sotos syndrome

(2010) Martina P. Pasillas et al.   HUMAN MUTATION

Structural Survey of Zinc-Containing Proteins and Development of the Zinc AMBER Force Field (ZAFF)

(2010) Martin B. Peters et al.   Journal of Chemical Theory and Computation

Mechanism and regulation of acetylated histone binding by the tandem PHD finger of DPF3b

(2010) Lei Zeng et al.   NATURE

Role for the nuclear receptor-binding SET domain protein 1 (NSD1) methyltransferase in coordinating lysine 36 methylation at histone 3 with RNA polymerase II function

(2010) A. K. Lucio-Eterovic et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tautomeric states of the active-site histidines of phosphorylated and unphosphorylated IIIGlc, a signal-transducing protein from escherichia coli, using two-dimensional heteronuclear NMR techniques

(2010) J.G. Pelton et al.   PROTEIN SCIENCE

Toward an Accurate Density-Functional Tight-Binding Description of Zinc-Containing Compounds

(2009) Ney H. Moreira et al.   Journal of Chemical Theory and Computation

Toward a Practical Method for Adaptive QM/MM Simulations

(2009) Rosa E. Bulo et al.   Journal of Chemical Theory and Computation

Epigenetic inactivation of the Sotos overgrowth syndrome gene histone methyltransferase NSD1 in human neuroblastoma and glioma

(2009) M. Berdasco et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Zinc Finger of NEMO Is a Functional Ubiquitin-binding Domain

(2008) Florence Cordier et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Preferential Dimethylation of Histone H4 Lysine 20 by Suv4-20

(2008) Hongbo Yang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Decoding of Methylated Histone H3 Tail by the Pygo-BCL9 Wnt Signaling Complex

(2008) Marc Fiedler et al.   MOLECULAR CELL