A multi-step model for facilitated unwinding of the yeast U4/U6 RNA duplex

Structural Analysis of Multi-Helical RNAs by NMR–SAXS/WAXS: Application to the U4/U6 di-snRNA

(2016) Gabriel Cornilescu et al.   JOURNAL OF MOLECULAR BIOLOGY

Cryo-EM structure of the yeast U4/U6.U5 tri-snRNP at 3.7 Å resolution

(2016) Thi Hoang Duong Nguyen et al.   NATURE

Substrate-assisted mechanism of RNP disruption by the spliceosomal Brr2 RNA helicase

(2016) Matthias Theuser et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The 3.8 A structure of the U4/U6.U5 tri-snRNP: Insights into spliceosome assembly and catalysis

(2016) R. Wan et al.   SCIENCE

Modelling Toehold-Mediated RNA Strand Displacement

(2015) Petr Šulc et al.   BIOPHYSICAL JOURNAL

Assembly and dynamics of the U4/U6 di-snRNP by single-molecule FRET

(2015) John W. Hardin et al.   NUCLEIC ACIDS RESEARCH

Structural requirements for protein-catalyzed annealing of U4 and U6 RNAs during di-snRNP assembly

(2015) Allison L. Didychuk et al.   NUCLEIC ACIDS RESEARCH

Conformational dynamics of stem II of the U2 snRNA

(2015) Margaret L. Rodgers et al.   RNA

Spliceosome assembly in the absence of stable U4/U6 RNA pairing

(2015) Jordan E. Burke et al.   RNA

Structure of a yeast spliceosome at 3.6-angstrom resolution

(2015) Chuangye Yan et al.   SCIENCE

A composite double-/single-stranded RNA-binding region in protein Prp3 supports tri-snRNP stability and splicing

(2015) Sunbin Liu et al.   eLife

Core structure of the U6 small nuclear ribonucleoprotein at 1.7-Å resolution

(2014) Eric J Montemayor et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structural basis for dual roles of Aar2p in U5 snRNP assembly

(2013) G. Weber et al.   GENES & DEVELOPMENT

Sad1 Counteracts Brr2-Mediated Dissociation of U4/U6.U5 in Tri-snRNP Homeostasis

(2013) Y.-H. Huang et al.   MOLECULAR AND CELLULAR BIOLOGY

RNA catalyses nuclear pre-mRNA splicing

(2013) Sebastian M. Fica et al.   NATURE

On the biophysics and kinetics of toehold-mediated DNA strand displacement

(2013) Niranjan Srinivas et al.   NUCLEIC ACIDS RESEARCH

Spliceosome activation: U4 is the path, stem I is the goal, and Prp8 is the keeper. Let's cheer for the ATPase Brr2!

(2012) K. H. Nielsen et al.   GENES & DEVELOPMENT

Brr2p-mediated conformational rearrangements in the spliceosome during activation and substrate repositioning

(2012) D. Hahn et al.   GENES & DEVELOPMENT

The Prp8 RNase H-like domain inhibits Brr2-mediated U4/U6 snRNA unwinding by blocking Brr2 loading onto the U4 snRNA

(2012) S. Mozaffari-Jovin et al.   GENES & DEVELOPMENT

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

New insights into the spliceosome by single molecule fluorescence microscopy

(2011) Aaron A Hoskins et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Exon Definition Complexes Contain the Tri-snRNP and Can Be Directly Converted into B-like Precatalytic Splicing Complexes

(2010) Marc Schneider et al.   MOLECULAR CELL

Learning Rates and States from Biophysical Time Series: A Bayesian Approach to Model Selection and Single-Molecule FRET Data

(2009) Jonathan E. Bronson et al.   BIOPHYSICAL JOURNAL

The Spliceosome: Design Principles of a Dynamic RNP Machine

(2009) Markus C. Wahl et al.   CELL

The Evolutionarily Conserved Core Design of the Catalytic Activation Step of the Yeast Spliceosome

(2009) Patrizia Fabrizio et al.   MOLECULAR CELL