Prediction of developmental chemical toxicity based on gene networks of human embryonic stem cells

A Quantitative Toxicogenomics Assay for High-throughput and Mechanistic Genotoxicity Assessment and Screening of Environmental Pollutants

(2016) Jiaqi Lan et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

High-throughput, quantitative assessment of the effects of low-dose silica nanoparticles on lung cells: grasping complex toxicity with a great depth of field

(2015) Cédric Pisani et al.   BMC GENOMICS

An evaluation of in-house and off-the-shelf in silico models: Implications on guidance for mutagenicity assessment

(2015) Robert Jolly et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

An Overview of Data Mining Algorithms in Drug Induced Toxicity Prediction

(2014) Ankur Omer et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Neurotoxin-Induced Pathway Perturbation in Human Neuroblastoma SH-EP Cells

(2014) Jin Hwan Do   MOLECULES AND CELLS

Prenatal Exposure to BPA Alters the Epigenome of the Rat Mammary Gland and Increases the Propensity to Neoplastic Development

(2014) Eugen Dhimolea et al.   PLoS One

Bisphenol A induce ovarian cancer cell migration via the MAPK and PI3K/Akt signalling pathways

(2014) Anna Ptak et al.   TOXICOLOGY LETTERS

How Diverse Are Diversity Assessment Methods? A Comparative Analysis and Benchmarking of Molecular Descriptor Space

(2013) Alexios Koutsoukas et al.   Journal of Chemical Information and Modeling

Chemical predictive modelling to improve compound quality

(2013) John G. Cumming et al.   NATURE REVIEWS DRUG DISCOVERY

Hazard Evaluation Support System (HESS) for predicting repeated dose toxicity using toxicological categories

(2013) Y. Sakuratani et al.   SAR AND QSAR IN ENVIRONMENTAL RESEARCH

The influence of study design and sex-differences on results from developmental neurotoxicity studies of bisphenol A, implications for toxicity testing

(2013) Anna Beronius et al.   TOXICOLOGY

A transcriptomics-based in vitro assay for predicting chemical genotoxicity in vivo

(2012) C. Magkoufopoulou et al.   CARCINOGENESIS

Compound selection for in vitro modeling of developmental neurotoxicity

(2012) Suzanne Kadereit   Frontiers in Bioscience-Landmark

Predictive Toxicology Modeling: Protocols for Exploring hERG Classification and Tetrahymena pyriformis End Point Predictions

(2012) Bo-Han Su et al.   Journal of Chemical Information and Modeling

Evaluation of DNA microarray results in the Toxicogenomics Project (TGP) consortium in Japan

(2012) Nakatsu Noriyuki et al.   JOURNAL OF TOXICOLOGICAL SCIENCES

In silicotoxicity prediction by support vector machine and SMILES representation-based string kernel

(2012) D.-S. Cao et al.   SAR AND QSAR IN ENVIRONMENTAL RESEARCH

Effects of methylmercury exposure on neuronal differentiation of mouse and human embryonic stem cells

(2012) Xiaoming He et al.   TOXICOLOGY LETTERS

pROC: an open-source package for R and S+ to analyze and compare ROC curves

(2011) Xavier Robin et al.   BMC BIOINFORMATICS

Predicting Drug-Induced Hepatotoxicity Using QSAR and Toxicogenomics Approaches

(2011) Yen Low et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Opportunities for Use of Human iPS Cells in Predictive Toxicology

(2011) B D Anson et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Prenatal exposure to permethrin influences vascular development of fetal brain and adult behavior in mice offspring

(2011) Satoshi Imanishi et al.   ENVIRONMENTAL TOXICOLOGY

Multi-Parametric Profiling Network Based on Gene Expression and Phenotype Data: A Novel Approach to Developmental Neurotoxicity Testing

(2011) Reiko Nagano et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

QSAR modelling of integrin antagonists using enhanced Bayesian regularised genetic neural networks

(2011) M. Jalali-Heravi et al.   SAR AND QSAR IN ENVIRONMENTAL RESEARCH

Transcriptomic Concentration-Response Evaluation of Valproic Acid, Cyproconazole, and Hexaconazole in the Neural Embryonic Stem Cell Test (ESTn)

(2011) Peter T. Theunissen et al.   TOXICOLOGICAL SCIENCES

BeadArray Expression Analysis Using Bioconductor

(2011) Matthew E. Ritchie et al.   PLoS Computational Biology

In vitro gene regulatory networks predict in vivo function of liver

(2010) Youping Deng et al.   BMC Systems Biology

Identification of a Primary Target of Thalidomide Teratogenicity

(2010) T. Ito et al.   SCIENCE

Mechanism-based selection of compounds for the development of innovative in vitro approaches to hepatotoxicity studies in the LIINTOP project

(2010) María José Gómez-Lechón et al.   TOXICOLOGY IN VITRO

The Toxicity Data Landscape for Environmental Chemicals

(2008) Richard Judson et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Bisphenol A prevents the synaptogenic response to estradiol in hippocampus and prefrontal cortex of ovariectomized nonhuman primates

(2008) C. Leranth et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA