Molecular dynamics simulations reveal the balance of forces governing the formation of a guanine tetrad—a common structural unit of G-quadruplex DNA

Extended molecular dynamics of ac-kitpromoter quadruplex

(2015) Barira Islam et al.   NUCLEIC ACIDS RESEARCH

G-quadruplexes and their regulatory roles in biology

(2015) Daniela Rhodes et al.   NUCLEIC ACIDS RESEARCH

Formation of G-Quadruplexes in Poly-G Sequences: Structure of a Propeller-Type Parallel-Stranded G-Quadruplex Formed by a G15 Stretch

(2014) Anjali Sengar et al.   BIOCHEMISTRY

Existence and consequences of G-quadruplex structures in DNA

(2014) Pierre Murat et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Folding and Unfolding Pathways of the Human Telomeric G-Quadruplex

(2014) Robert D. Gray et al.   JOURNAL OF MOLECULAR BIOLOGY

Direct Quantification of Loop Interaction and π–π Stacking for G-Quadruplex Stability at the Submolecular Level

(2014) Chiran Ghimire et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Dynamics and stability of polymorphic human telomeric G-quadruplex under tension

(2014) Huijuan You et al.   NUCLEIC ACIDS RESEARCH

Flexibility and structural conservation in a c-KIT G-quadruplex

(2014) Dengguo Wei et al.   NUCLEIC ACIDS RESEARCH

G-quadruplex formation in telomeres enhances POT1/TPP1 protection against RPA binding

(2014) S. Ray et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Direct Measurement of Sequential Folding Pathway and Energy Landscape of Human Telomeric G-quadruplex Structures

(2013) Wei Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Relative Stability of Different DNA Guanine Quadruplex Stem Topologies Derived Using Large-Scale Quantum-Chemical Computations

(2013) Jiří Šponer et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Quantitative visualization of DNA G-quadruplex structures in human cells

(2013) Giulia Biffi et al.   Nature Chemistry

Detection of G-quadruplex DNA in mammalian cells

(2013) A. Henderson et al.   NUCLEIC ACIDS RESEARCH

Conformational dynamics of the human propeller telomeric DNA quadruplex on a microsecond time scale

(2013) Barira Islam et al.   NUCLEIC ACIDS RESEARCH

Structure of the human telomere in Na+ solution: an antiparallel (2+2) G-quadruplex scaffold reveals additional diversity

(2013) Kah Wai Lim et al.   NUCLEIC ACIDS RESEARCH

Thermodynamics-Hydration Relationships within Loops That Affect G-Quadruplexes under Molecular Crowding Conditions

(2012) Takeshi Fujimoto et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Click Chemistry Assisted Single-Molecule Fingerprinting Reveals a 3D Biomolecular Folding Funnel

(2012) Zhongbo Yu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Energetic Basis of Human Telomeric DNA Folding into G-Quadruplex Structures

(2012) Matjaž Bončina et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

DNA secondary structures: stability and function of G-quadruplex structures

(2012) Matthew L. Bochman et al.   NATURE REVIEWS GENETICS

Guanine base stacking in G-quadruplex nucleic acids

(2012) Christopher Jacques Lech et al.   NUCLEIC ACIDS RESEARCH

Kinetic and Thermodynamic Control of G-Quadruplex Folding

(2011) Yong Xue et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

N-Cyclic Bay-Substituted Perylene G-Quadruplex Ligands Have Selective Antiproliferative Effects on Cancer Cells and Induce Telomere Damage

(2011) Valentina Casagrande et al.   JOURNAL OF MEDICINAL CHEMISTRY

Structure of Human Telomeric DNA in Crowded Solution

(2011) Brahim Heddi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Explaining the varied glycosidic conformational, G-tract length and sequence preferences for anti-parallel G-quadruplexes

(2011) Xiaohui Cang et al.   NUCLEIC ACIDS RESEARCH

Single Molecule Studies of Physiologically Relevant Telomeric Tails Reveal POT1 Mechanism for Promoting G-quadruplex Unfolding

(2010) Hong Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Selectivity in Ligand Recognition of G-Quadruplex Loops†

(2009) Nancy H. Campbell et al.   BIOCHEMISTRY

Characterization of a K+-Induced Conformational Switch in a Human Telomeric DNA Oligonucleotide Using 2-Aminopurine Fluorescence

(2009) Robert D. Gray et al.   BIOCHEMISTRY

PLUMED: A portable plugin for free-energy calculations with molecular dynamics

(2009) Massimiliano Bonomi et al.   COMPUTER PHYSICS COMMUNICATIONS

Human telomeric G-quadruplex: thermodynamic and kinetic studies of telomeric quadruplex stability

(2009) Jonathan B. Chaires   FEBS Journal

Human telomeric G-quadruplex: The current status of telomeric G-quadruplexes as therapeutic targets in human cancer

(2009) Stephen Neidle   FEBS Journal

A G-Rich Sequence within thec-kitOncogene Promoter Forms a Parallel G-Quadruplex Having Asymmetric G-Tetrad Dynamics

(2009) Shang-Te Danny Hsu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structure of the Human Telomere in K+Solution: A Stable Basket-Type G-Quadruplex with Only Two G-Tetrad Layers

(2009) Kah Wai Lim et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

GROMACS 4:  Algorithms for Highly Efficient, Load-Balanced, and Scalable Molecular Simulation

(2008) Berk Hess et al.   Journal of Chemical Theory and Computation

Effect of loop length variation on quadruplex-Watson Crick duplex competition

(2008) Niti Kumar et al.   NUCLEIC ACIDS RESEARCH

Conserved elements with potential to form polymorphic G-quadruplex structures in the first intron of human genes

(2008) Johanna Eddy et al.   NUCLEIC ACIDS RESEARCH

Stability and kinetics of G-quadruplex structures

(2008) A. N. Lane et al.   NUCLEIC ACIDS RESEARCH

P-LINCS:  A Parallel Linear Constraint Solver for Molecular Simulation

(2007) Berk Hess   Journal of Chemical Theory and Computation