Histone H2B monoubiquitination is a critical epigenetic switch for the regulation of autophagy

Writing and reading H2B monoubiquitylation

(2014) Gilad Fuchs et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Histone H2B monoubiquitination: roles to play in human malignancy

(2014) Alexander J Cole et al.   ENDOCRINE-RELATED CANCER

Transcriptional regulation of autophagy by an FXR–CREB axis

(2014) Sunmi Seok et al.   NATURE

Nutrient-sensing nuclear receptors coordinate autophagy

(2014) Jae Man Lee et al.   NATURE

Beclin 2 Functions in Autophagy, Degradation of G Protein-Coupled Receptors, and Metabolism

(2013) Congcong He et al.   CELL

Transient Activation of Autophagy via Sox2-Mediated Suppression of mTOR Is an Important Early Step in Reprogramming to Pluripotency

(2013) Shuo Wang et al.   Cell Stem Cell

Bcl-3, induced by Tax and HTLV-1, inhibits NF-κB activation and promotes autophagy

(2013) Jinheng Wang et al.   CELLULAR SIGNALLING

USP49 deubiquitinates histone H2B and regulates cotranscriptional pre-mRNA splicing

(2013) Z. Zhang et al.   GENES & DEVELOPMENT

Epigenetic Regulation of Autophagy by the Methyltransferase G9a

(2013) A. Artal-Martinez de Narvajas et al.   MOLECULAR AND CELLULAR BIOLOGY

The histone H4 lysine 16 acetyltransferase hMOF regulates the outcome of autophagy

(2013) Jens Füllgrabe et al.   NATURE

The return of the nucleus: transcriptional and epigenetic control of autophagy

(2013) Jens Füllgrabe et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Autophagy in Human Health and Disease

(2013) Augustine M.K. Choi et al.   NEW ENGLAND JOURNAL OF MEDICINE

Modulation of the autophagy pathway by human tumor viruses

(2013) Lindsey M. Silva et al.   SEMINARS IN CANCER BIOLOGY

Molecular mechanisms of selective autophagy

(2012) G M Fimia et al.   CELL DEATH AND DIFFERENTIATION

Ubiquitination and selective autophagy

(2012) S Shaid et al.   CELL DEATH AND DIFFERENTIATION

Histone H2B lysine 120 monoubiquitination is required for embryonic stem cell differentiation

(2012) Su Chen et al.   CELL RESEARCH

The enigmatic role of H2Bub1 in cancer

(2012) Steven A. Johnsen   FEBS LETTERS

BRCA1/BARD1 E3 Ubiquitin Ligase Can Modify Histones H2A and H2B in the Nucleosome Particle

(2012) Amit Thakar et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Dynamic Loss of H2B Ubiquitylation without Corresponding Changes in H3K4 Trimethylation during Myogenic Differentiation

(2012) V. Vethantham et al.   MOLECULAR AND CELLULAR BIOLOGY

The Histone H2B Monoubiquitination Regulatory Pathway Is Required for Differentiation of Multipotent Stem Cells

(2012) Oleksandra Karpiuk et al.   MOLECULAR CELL

RNF20 and USP44 Regulate Stem Cell Differentiation by Modulating H2B Monoubiquitylation

(2012) Gilad Fuchs et al.   MOLECULAR CELL

Exercise-induced BCL2-regulated autophagy is required for muscle glucose homeostasis

(2012) Congcong He et al.   NATURE

Coupling of Glucose Deprivation with Impaired Histone H2B Monoubiquitination in Tumors

(2012) Yasuyo Urasaki et al.   PLoS One

Histone deacetylases 1 and 2 regulate autophagy flux and skeletal muscle homeostasis in mice

(2012) V. Moresi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Selective autophagy mediated by autophagic adapter proteins

(2011) Terje Johansen et al.   Autophagy

Role for Dpy-30 in ES Cell-Fate Specification by Regulation of H3K4 Methylation within Bivalent Domains

(2011) Hao Jiang et al.   CELL

The diverse functions of Dot1 and H3K79 methylation

(2011) A. T. Nguyen et al.   GENES & DEVELOPMENT

The tumor suppressor CDC73 interacts with the ring finger proteins RNF20 and RNF40 and is required for the maintenance of histone 2B monoubiquitination

(2011) Michael A. Hahn et al.   HUMAN MOLECULAR GENETICS

Spermidine and resveratrol induce autophagy by distinct pathways converging on the acetylproteome

(2011) Eugenia Morselli et al.   JOURNAL OF CELL BIOLOGY

Requirement of ATM-Dependent Monoubiquitylation of Histone H2B for Timely Repair of DNA Double-Strand Breaks

(2011) Lilach Moyal et al.   MOLECULAR CELL

Blocking NF-κB nuclear translocation leads to p53-related autophagy activation and cell apoptosis

(2011) Bao-Song Zhu   WORLD JOURNAL OF GASTROENTEROLOGY

Overview of macroautophagy regulation in mammalian cells

(2010) Maryam Mehrpour et al.   CELL RESEARCH

A Genome-Wide siRNA Screen Reveals Multiple mTORC1 Independent Signaling Pathways Regulating Autophagy under Normal Nutritional Conditions

(2010) Marta M. Lipinski et al.   DEVELOPMENTAL CELL

Histone H2B ubiquitination and beyond

(2010) Mahesh B. Chandrasekharan et al.   Epigenetics

Regulation of Histone H2A and H2B Deubiquitination andXenopusDevelopment by USP12 and USP46

(2010) Heui-Yun Joo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Autophagy negatively regulates Wnt signalling by promoting Dishevelled degradation

(2010) Chan Gao et al.   NATURE CELL BIOLOGY

Eaten alive: a history of macroautophagy

(2010) Zhifen Yang et al.   NATURE CELL BIOLOGY

When autophagy meets viruses: a double-edged sword with functions in defense and offense

(2010) Hee Jin Kim et al.   Seminars in Immunopathology

Caloric restriction and resveratrol promote longevity through the Sirtuin-1-dependent induction of autophagy

(2010) E Morselli et al.   Cell Death & Disease

RAD6-Mediated Transcription-Coupled H2B Ubiquitylation Directly Stimulates H3K4 Methylation in Human Cells

(2009) Jaehoon Kim et al.   CELL

Mammalian autophagy: core molecular machinery and signaling regulation

(2009) Zhifen Yang et al.   CURRENT OPINION IN CELL BIOLOGY

Critical Roles of Coactivator p300 in Mouse Embryonic Stem Cell Differentiation and Nanog Expression

(2009) Xiaomin Zhong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Histone H2BK123 monoubiquitination is the critical determinant for H3K4 and H3K79 trimethylation by COMPASS and Dot1

(2009) Shima Nakanishi et al.   JOURNAL OF CELL BIOLOGY

Diet, Autophagy, and Cancer: A Review

(2008) K. Singletary et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Autophagy in the Pathogenesis of Disease

(2008) Beth Levine et al.   CELL

Molecular implementation and physiological roles for histone H3 lysine 4 (H3K4) methylation

(2008) Ali Shilatifard   CURRENT OPINION IN CELL BIOLOGY

The Putative Cancer Stem Cell Marker USP22 Is a Subunit of the Human SAGA Complex Required for Activated Transcription and Cell-Cycle Progression

(2008) Xiao-Yong Zhang et al.   MOLECULAR CELL

A TFTC/STAGA Module Mediates Histone H2A and H2B Deubiquitination, Coactivates Nuclear Receptors, and Counteracts Heterochromatin Silencing

(2008) Yue Zhao et al.   MOLECULAR CELL

Autophagy fights disease through cellular self-digestion

(2008) Noboru Mizushima et al.   NATURE

Monoubiquitinated H2B is associated with the transcribed region of highly expressed genes in human cells

(2008) Neri Minsky et al.   NATURE CELL BIOLOGY

A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy

(2008) I. H. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA