Artificial Metalloenzymes in Asymmetric Catalysis: Key Developments and Future Directions

Lipase active site covalent anchoring of Rh(NHC) catalysts: towards chemoselective artificial metalloenzymes

(2015) M. Basauri-Molina et al.   CHEMICAL COMMUNICATIONS

Novel artificial metalloenzymes by in vivo incorporation of metal-binding unnatural amino acids

(2015) Ivana Drienovská et al.   Chemical Science

Toward the Computational Design of Artificial Metalloenzymes: From Protein–Ligand Docking to Multiscale Approaches

(2015) Victor Muñoz Robles et al.   ACS Catalysis

Mysteries of Metals in Metalloenzymes

(2014) Crystal E. Valdez et al.   ACCOUNTS OF CHEMICAL RESEARCH

Polymer Enzyme Conjugates as Chiral Ligands for Sharpless Dihydroxylation of Alkenes in Organic Solvents

(2014) Stefan Konieczny et al.   CHEMBIOCHEM

Expanding the Chemical Diversity in Artificial Imine Reductases Based on the Biotin-Streptavidin Technology

(2014) Tommaso Quinto et al.   ChemCatChem

Quantum Chemical Studies of Mechanisms for Metalloenzymes

(2014) Margareta R. A. Blomberg et al.   CHEMICAL REVIEWS

Hybrid Ruthenium ROMP Catalysts Based on an Engineered Variant of β-Barrel Protein FhuA ΔCVFtev: Effect of Spacer Length

(2014) Daniel F. Sauer et al.   Chemistry-An Asian Journal

Artificial metalloenzymes for enantioselective catalysis

(2014) Jeffrey Bos et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Artificial metalloenzymes derived from bovine β-lactoglobulin for the asymmetric transfer hydrogenation of an aryl ketone – synthesis, characterization and catalytic activity

(2014) Alice Chevalley et al.   DALTON TRANSACTIONS

Structural, Kinetic, and Docking Studies of Artificial Imine Reductases Based on Biotin–Streptavidin Technology: An Induced Lock-and-Key Hypothesis

(2014) Victor Muñoz Robles et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Computational Insights on an Artificial Imine Reductase Based on the Biotin–Streptavidin Technology

(2014) Victor Muñoz Robles et al.   ACS Catalysis

Co-immobilization of an Enzyme and a Metal into the Compartments of Mesoporous Silica for Cooperative Tandem Catalysis: An Artificial Metalloenzyme

(2013) Karin Engström et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

An Artificial Oxygenase Built from Scratch: Substrate Binding Site Identified Using a Docking Approach

(2013) Charlène Esmieu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Biotinylated Metathesis Catalysts: Synthesis and Performance in Ring Closing Metathesis

(2013) Anna Kajetanowicz et al.   CATALYSIS LETTERS

A General Method for Artificial Metalloenzyme Formation through Strain-Promoted Azide-Alkyne Cycloaddition

(2013) Hao Yang et al.   CHEMBIOCHEM

Artificial Copper Enzymes for Asymmetric Diels-Alder Reactions

(2013) Peter J. Deuss et al.   ChemCatChem

Synthesis of heterogeneous enzyme–metal nanoparticle biohybrids in aqueous media and their applications in C–C bond formation and tandem catalysis

(2013) Marco Filice et al.   CHEMICAL COMMUNICATIONS

A Dual Anchoring Strategy for the Localization and Activation of Artificial Metalloenzymes Based on the Biotin–Streptavidin Technology

(2013) Jeremy M. Zimbron et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Human carbonic anhydrase II as host protein for the creation of artificial metalloenzymes: the asymmetric transfer hydrogenation of imines

(2013) Fabien W. Monnard et al.   Chemical Science

An enantioselective artificial metallo-hydratase

(2013) Jeffrey Bos et al.   Chemical Science

Genetic Optimization of the Catalytic Efficiency of Artificial Imine Reductases Based on Biotin–Streptavidin Technology

(2013) Fabian Schwizer et al.   ACS Catalysis

Artificial Metalloenzymes and Metallopeptide Catalysts for Organic Synthesis

(2013) Jared C. Lewis   ACS Catalysis

Dynamic Kinetic ResolutionviaHydrolase-Metal Combo Catalysis in Stereoselective Synthesis of Bioactive Compounds

(2012) Pilar Hoyos et al.   ADVANCED SYNTHESIS & CATALYSIS

Enantioselective Artificial Metalloenzymes by Creation of a Novel Active Site at the Protein Dimer Interface

(2012) Jeffrey Bos et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Aqueous phase transfer hydrogenation of aryl ketones catalysed by achiral ruthenium(II) and rhodium(III) complexes and their papain conjugates

(2012) Nathalie Madern et al.   APPLIED ORGANOMETALLIC CHEMISTRY

Enantioselective transfer hydrogenation of ketone catalysed by artificial metalloenzymes derived from bovine β-lactoglobulin

(2012) Alice Chevalley et al.   CHEMICAL COMMUNICATIONS

Synthetic cascades are enabled by combining biocatalysts with artificial metalloenzymes

(2012) V. Köhler et al.   Nature Chemistry

Olefin Cyclopropanation via Carbene Transfer Catalyzed by Engineered Cytochrome P450 Enzymes

(2012) P. S. Coelho et al.   SCIENCE

Biotinylated Rh(III) Complexes in Engineered Streptavidin for Accelerated Asymmetric C-H Activation

(2012) T. K. Hyster et al.   SCIENCE

The Growing Impact of Catalysis in the Pharmaceutical Industry

(2011) Carl A. Busacca et al.   ADVANCED SYNTHESIS & CATALYSIS

OsO4⋅Streptavidin: A Tunable Hybrid Catalyst for the Enantioselective cis-Dihydroxylation of Olefins

(2011) Valentin Köhler et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Platinum Nanoparticles Encapsulated by Aminopeptidase: A Multifunctional Bioinorganic Nanohybrid Catalyst

(2011) Boi Hoa San et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Artificial Transfer Hydrogenases for the Enantioselective Reduction of Cyclic Imines

(2011) Marc Dürrenberger et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Incorporation of Manganese Complexes into Xylanase: New Artificial Metalloenzymes for Enantioselective Epoxidation

(2011) Mathieu Allard et al.   CHEMBIOCHEM

Merging the best of two worlds: artificial metalloenzymes for enantioselective catalysis

(2011) Mark R. Ringenberg et al.   CHEMICAL COMMUNICATIONS

Artificial metalloenzymes for olefin metathesis based on the biotin-(strept)avidin technology

(2011) Cheikh Lo et al.   CHEMICAL COMMUNICATIONS

An artificial metalloenzyme for olefin metathesis

(2011) Clemens Mayer et al.   CHEMICAL COMMUNICATIONS

Bioinspired Catalyst Design and Artificial Metalloenzymes

(2011) Peter J. Deuss et al.   CHEMISTRY-A EUROPEAN JOURNAL

Choosing an effective protein bioconjugation strategy

(2011) Nicholas Stephanopoulos et al.   Nature Chemical Biology

Chemically engineered papain as artificial formate dehydrogenase for NAD(P)H regeneration

(2011) Pierre Haquette et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

An Artificial Metalloenzyme: Creation of a Designed Copper Binding Site in a Thermostable Protein

(2010) John Podtetenieff et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Highly Efficient and Site-Selective Phosphane Modification of Proteins through Hydrazone Linkage: Development of Artificial Metalloenzymes

(2010) Peter J. Deuss et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Artificial Metalloenzymes through Cysteine-Selective Conjugation of Phosphines to Photoactive Yellow Protein

(2010) Wouter Laan et al.   CHEMBIOCHEM

Regioselective Hydroformylation of Styrene Using Rhodium-Substituted Carbonic Anhydrase

(2010) Qing Jing et al.   ChemCatChem

Artificial Metalloenzymes

(2010) Fiora Rosati et al.   ChemCatChem

Dynamic Kinetic Resolution of Amines and Amino Acids by Enzyme-Metal Cocatalysis

(2010) Yunwoong Kim et al.   ChemCatChem

(η6-Arene) ruthenium(ii) complexes and metallo-papain hybrid as Lewis acid catalysts of Diels–Alder reaction in water

(2010) Barisa Talbi et al.   DALTON TRANSACTIONS

Synthesis of hybrid transition-metalloproteins via thiol-selective covalent anchoring of Rh-phosphine and Ru-phenanthroline complexes

(2010) René den Heeten et al.   DALTON TRANSACTIONS

Mechanism of Accumulation and Incorporation of Organometallic Pd Complexes into the Protein Nanocage of apo-Ferritin

(2010) Satoshi Abe et al.   INORGANIC CHEMISTRY

Solid-State Structural Characterization of Cutinase-ECE-Pincer-Metal Hybrids

(2009) Lucy Rutten et al.   CHEMISTRY-A EUROPEAN JOURNAL

Stereoselective Hydrogenation of Olefins Using Rhodium-Substituted Carbonic Anhydrase-A New Reductase

(2009) Qing Jing et al.   CHEMISTRY-A EUROPEAN JOURNAL

Improving the enantioselectivity of artificial transfer hydrogenases based on the biotin–streptavidin technology by combinations of point mutations

(2009) A. Pordea et al.   INORGANICA CHIMICA ACTA

Genetic Incorporation of a Metal-Ion Chelating Amino Acid into Proteins as a Biophysical Probe

(2009) Hyun Soo Lee et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Process of Accumulation of Metal Ions on the Interior Surface of apo-Ferritin: Crystal Structures of a Series of apo-Ferritins Containing Variable Quantities of Pd(II) Ions

(2009) Takafumi Ueno et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Polymerization of Phenylacetylene by Rhodium Complexes within a Discrete Space of apo-Ferritin

(2009) Satoshi Abe et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Selective oxidation of aromatic sulfide catalyzed by an artificial metalloenzyme: new activity of hemozymes

(2009) Rémy Ricoux et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Artificial Metalloenzymes for Asymmetric Allylic Alkylation on the Basis of the Biotin–Avidin Technology

(2008) Julien Pierron et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

X-Ray Structure and Designed Evolution of an Artificial Transfer Hydrogenase

(2008) Marc Creus et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Robust Protein Host for Anchoring Chelating Ligands and Organocatalysts

(2008) Manfred T. Reetz et al.   CHEMBIOCHEM

Non-Tethered Organometallic Phosphonate Inhibitors for Lipase Inhibition: Positioning of the Metal Center in the Active Site of Cutinase

(2008) Cornelis A. Kruithof et al.   EUROPEAN JOURNAL OF INORGANIC CHEMISTRY

Incorporation of biotinylated manganese-salen complexes into streptavidin: New artificial metalloenzymes for enantioselective sulfoxidation

(2008) A. Pordea et al.   JOURNAL OF ORGANOMETALLIC CHEMISTRY

Biosynthesis of a Site-Specific DNA Cleaving Protein

(2008) Hyun Soo Lee et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Control of the Coordination Structure of Organometallic Palladium Complexes in an apo-Ferritin Cage

(2008) Satoshi Abe et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Artificial Metalloenzyme for Enantioselective Sulfoxidation Based on Vanadyl-Loaded Streptavidin

(2008) Anca Pordea et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

X-ray Structure of Candida antarctica Lipase A Shows a Novel Lid Structure and a Likely Mode of Interfacial Activation

(2007) Daniel J. Ericsson et al.   JOURNAL OF MOLECULAR BIOLOGY