Single-cell analyses implicate ascites in remodeling the ecosystems of primary and metastatic tumors in ovarian cancer

Cancer statistics, 2022

(2022) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Ovarian cancer immunogenicity is governed by a narrow subset of progenitor tissue-resident memory T cells

(2022) Carmen M. Anadon et al.   CANCER CELL

Tissue-resident FOLR2+ macrophages associate with CD8+ T cell infiltration in human breast cancer

(2022) Rodrigo Nalio Ramos et al.   CELL

Human dendritic cells in cancer

(2022) Egle Kvedaraite et al.   Science Immunology

A pan-cancer single-cell transcriptional atlas of tumor infiltrating myeloid cells

(2021) Sijin Cheng et al.   CELL

Single-cell dissection of cellular components and interactions shaping the tumor immune phenotypes in ovarian cancer

(2021) Milena Hornburg et al.   CANCER CELL

STARTRAC analyses of scRNAseq data from tumor models reveal T cell dynamics and therapeutic targets

(2021) Dev Bhatt et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Circulating mucosal-associated invariant T cells identify patients responding to anti-PD-1 therapy

(2021) Sara De Biasi et al.   Nature Communications

Tissue-resident macrophages provide a pro-tumorigenic niche to early NSCLC cells

(2021) María Casanova-Acebes et al.   NATURE

A single-cell and spatially resolved atlas of human breast cancers

(2021) Sunny Z. Wu et al.   NATURE GENETICS

Spatiotemporal Immune Landscape of Colorectal Cancer Liver Metastasis at Single-Cell Level

(2021) Yingcheng Wu et al.   Cancer Discovery

Human prostate cancer bone metastases have an actionable immunosuppressive microenvironment

(2021) Youmna Kfoury et al.   CANCER CELL

Differential abundance testing on single-cell data using k-nearest neighbor graphs

(2021) Emma Dann et al.   NATURE BIOTECHNOLOGY

Pan-cancer single-cell landscape of tumor-infiltrating T cells

(2021) Liangtao Zheng et al.   SCIENCE

Lung mesenchymal stromal cells influenced by Th2 cytokines mobilize neutrophils and facilitate metastasis by producing complement C3

(2021) Zhiyuan Zheng et al.   Nature Communications

MAIT cells are enriched and highly functional in ascites of patients with decompensated liver cirrhosis

(2020) Christian E. Niehaus et al.   HEPATOLOGY

Tissue-resident macrophages in omentum promote metastatic spread of ovarian cancer

(2020) Anders Etzerodt et al.   JOURNAL OF EXPERIMENTAL MEDICINE

CellPhoneDB: inferring cell–cell communication from combined expression of multi-subunit ligand–receptor complexes

(2020) Mirjana Efremova et al.   Nature Protocols

An Integrated Gene Expression Landscape Profiling Approach to Identify Lung Tumor Endothelial Cell Heterogeneity and Angiogenic Candidates

(2020) Jermaine Goveia et al.   CANCER CELL

Single-Cell Analyses Inform Mechanisms of Myeloid-Targeted Therapies in Colon Cancer

(2020) Lei Zhang et al.   CELL

A conserved dendritic-cell regulatory program limits antitumour immunity

(2020) Barbara Maier et al.   NATURE

Multi-omic analysis of subtype evolution and heterogeneity in high-grade serous ovarian carcinoma

(2020) Ludwig Geistlinger et al.   CANCER RESEARCH

A single-cell landscape of high-grade serous ovarian cancer

(2020) Benjamin Izar et al.   NATURE MEDICINE

SnapShot: FABP Functions

(2020) Bing Li et al.   CELL

A molecular cell atlas of the human lung from single-cell RNA sequencing

(2020) Kyle J. Travaglini et al.   NATURE

Direct and Indirect Regulators of Epithelial-Mesenchymal Transition (EMT)-mediated Immunosuppression in Breast Carcinomas

(2020) Anushka Dongre et al.   Cancer Discovery

Tumour-associated macrophages-derived CXCL8 determines immune evasion through autonomous PD-L1 expression in gastric cancer

(2019) Chao Lin et al.   GUT

Efficacy and Safety of Avelumab for Patients With Recurrent or Refractory Ovarian Cancer

(2019) Mary L. Disis et al.   JAMA Oncology

Two distinct interstitial macrophage populations coexist across tissues in specific subtissular niches

(2019) Svetoslav Chakarov et al.   SCIENCE

Characterization of cell fate probabilities in single-cell data with Palantir

(2019) Manu Setty et al.   NATURE BIOTECHNOLOGY

Epithelial ovarian cancer

(2019) Stephanie Lheureux et al.   LANCET

The Immunobiology of the Interleukin-12 Family: Room for Discovery

(2019) Elia D. Tait Wojno et al.   IMMUNITY

Single-Cell Transcriptomics of Human and Mouse Lung Cancers Reveals Conserved Myeloid Populations across Individuals and Species

(2019) Rapolas Zilionis et al.   IMMUNITY

The Polycomb Repressor Complex 1 Drives Double-Negative Prostate Cancer Metastasis by Coordinating Stemness and Immune Suppression

(2019) Wenjing Su et al.   CANCER CELL

Fate Mapping via Ms4a3-Expression History Traces Monocyte-Derived Cells

(2019) Zhaoyuan Liu et al.   CELL

The biology and functional importance of MAIT cells

(2019) Dale I. Godfrey et al.   NATURE IMMUNOLOGY

Landscape and Dynamics of Single Immune Cells in Hepatocellular Carcinoma

(2019) Qiming Zhang et al.   CELL

TCF-1-Centered Transcriptional Network Drives an Effector versus Exhausted CD8 T Cell-Fate Decision

(2019) Zeyu Chen et al.   IMMUNITY

Global characterization of T cells in non-small-cell lung cancer by single-cell sequencing

(2018) Xinyi Guo et al.   NATURE MEDICINE

Lineage tracking reveals dynamic relationships of T cells in colorectal cancer

(2018) Lei Zhang et al.   NATURE

Cancer Associated Fibroblasts: Naughty Neighbors That Drive Ovarian Cancer Progression

(2018) Subramanyam Dasari et al.   Cancers

Phagocytosis imprints heterogeneity in tissue-resident macrophages

(2017) Noelia A-Gonzalez et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Cabozantinib Eradicates Advanced Murine Prostate Cancer by Activating Antitumor Innate Immunity

(2017) Akash Patnaik et al.   Cancer Discovery

Clear cell ovarian cancers with microsatellite instability: A unique subset of ovarian cancers with increased tumor-infiltrating lymphocytes and PD-1/PD-L1 expression

(2017) Brooke E. Howitt et al.   OncoImmunology

Tissue-Resident Macrophage Ontogeny and Homeostasis

(2016) Florent Ginhoux et al.   IMMUNITY

Hematogenous Metastasis of Ovarian Cancer: Rethinking Mode of Spread

(2014) Sunila Pradeep et al.   CANCER CELL

Role of Endothelial Cell Metabolism in Vessel Sprouting

(2013) Katrien De Bock et al.   Cell Metabolism

Getting to Know Ovarian Cancer Ascites: Opportunities for Targeted Therapy-Based Translational Research

(2013) Nuzhat Ahmed et al.   Frontiers in Oncology

Human NK cells at early stages of differentiation produce CXCL8 and express CD161 molecule that functions as an activating receptor

(2012) E. Montaldo et al.   BLOOD

NK cells impede glioblastoma virotherapy through NKp30 and NKp46 natural cytotoxicity receptors

(2012) Christopher A Alvarez-Breckenridge et al.   NATURE MEDICINE

The First Line of Intra-abdominal Metastatic Attack: Breaching the Mesothelial Cell Layer: Figure 1.

(2011) Hilary A. Kenny et al.   Cancer Discovery