Neural Basis of Benzodiazepine Reward: Requirement for α2 Containing GABAA Receptors in the Nucleus Accumbens

Cocaine-induced adaptations in D1 and D2 accumbens projection neurons (a dichotomy not necessarily synonymous with direct and indirect pathways)

(2013) Rachel J Smith et al.   CURRENT OPINION IN NEUROBIOLOGY

Patterns of mRNA and protein expression for 12 GABAA receptor subunits in the mouse brain

(2013) H. Hörtnagl et al.   NEUROSCIENCE

GABA Site Agonist Gaboxadol Induces Addiction-Predicting Persistent Changes in Ventral Tegmental Area Dopamine Neurons But Is Not Rewarding in Mice or Baboons

(2012) E. Vashchinkina et al.   JOURNAL OF NEUROSCIENCE

Benzodiazepine-induced anxiolysis and reduction of conditioned fear are mediated by distinct GABAA receptor subtypes in mice

(2012) Kiersten S. Smith et al.   NEUROPHARMACOLOGY

Differential Roles of GABAA Receptor Subtypes in Benzodiazepine-Induced Enhancement of Brain-Stimulation Reward

(2012) Lauren M Reynolds et al.   NEUROPSYCHOPHARMACOLOGY

Do initial responses to drugs predict future use or abuse?

(2012) Harriet de Wit et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

α2-containing GABAA receptors: A target for the development of novel treatment strategies for CNS disorders

(2012) Elif Engin et al.   PHARMACOLOGY & THERAPEUTICS

Dissecting the role of diazepam-sensitive γ-aminobutyric acid type A receptors in defensive behavioral reactivity to mild threat

(2012) Christina Koester et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Deletion of the gabra2 Gene Results in Hypersensitivity to the Acute Effects of Ethanol but Does Not Alter Ethanol Self Administration

(2012) Claire I. Dixon et al.   PLoS One

Modest abuse-related subjective effects of zolpidem in drug-naive volunteers

(2011) Stephanie C. Licata et al.   BEHAVIOURAL PHARMACOLOGY

Presynaptic  2-GABAA Receptors in Primary Afferent Depolarization and Spinal Pain Control

(2011) R. Witschi et al.   JOURNAL OF NEUROSCIENCE

Hooked on benzodiazepines: GABAA receptor subtypes and addiction

(2011) Kelly R. Tan et al.   TRENDS IN NEUROSCIENCES

Antidepressant-like properties of α2-containing GABAA receptors

(2010) Isabel Vollenweider et al.   BEHAVIOURAL BRAIN RESEARCH

Neural bases for addictive properties of benzodiazepines

(2010) Kelly R. Tan et al.   NATURE

Cocaine effects on mouse incentive-learning and human addiction are linked to  2 subunit-containing GABAA receptors

(2010) C. I. Dixon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cell Type-Specific Loss of BDNF Signaling Mimics Optogenetic Control of Cocaine Reward

(2010) M. K. Lobo et al.   SCIENCE

α1- and α2-containing GABA A receptor modulation is not necessary for benzodiazepine-induced hyperphagia

(2009) H.V. Morris et al.   APPETITE

Diazepam and cocaine potentiate brain stimulation reward in C57BL/6J mice

(2009) Carolin J. Straub et al.   BEHAVIOURAL BRAIN RESEARCH

Afferents to the GABAergic tail of the ventral tegmental area in the rat

(2009) Jennifer Kaufling et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Faithful Expression of Multiple Proteins via 2A-Peptide Self-Processing: A Versatile and Reliable Method for Manipulating Brain Circuits

(2009) W. Tang et al.   JOURNAL OF NEUROSCIENCE

Reducing Abuse Liability of GABAA/Benzodiazepine Ligands via Selective Partial Agonist Efficacy at  1 and  2/3 Subtypes

(2009) N. A. Ator et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

A Simplified Baculovirus-AAV Expression Vector System Coupled With One-step Affinity Purification Yields High-titer rAAV Stocks From Insect Cells

(2009) Richard H Smith et al.   MOLECULAR THERAPY

Long-lasting Modulation of Glutamatergic Transmission in VTA Dopamine Neurons after a Single Dose of Benzodiazepine Agonists

(2008) Anne E Heikkinen et al.   NEUROPSYCHOPHARMACOLOGY

Alpha2-containing GABAA receptors are involved in mediating stimulant effects of cocaine

(2008) H.V. Morris et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Abuse and dependence liability of benzodiazepine-type drugs: GABAA receptor modulation and beyond

(2008) Stephanie C. Licata et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Evidence for sugar addiction: Behavioral and neurochemical effects of intermittent, excessive sugar intake

(2007) Nicole M. Avena et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS