Tryptophan Metabolism and White Matter Integrity in Schizophrenia

Serotonin, tryptophan metabolism and the brain-gut-microbiome axis

(2015) S.M. O’Mahony et al.   BEHAVIOURAL BRAIN RESEARCH

Elevated levels of kynurenic acid during gestation produce neurochemical, morphological, and cognitive deficits in adulthood: Implications for schizophrenia

(2015) Michelle L. Pershing et al.   NEUROPHARMACOLOGY

Cortisol Reactivity to Stress and Its Association With White Matter Integrity in Adults With Schizophrenia

(2015) Katie L. Nugent et al.   PSYCHOSOMATIC MEDICINE

Alterations in frontal white matter neurochemistry and microstructure in schizophrenia: implications for neuroinflammation

(2015) J Chiappelli et al.   Translational Psychiatry

Quinolinic acid toxicity on oligodendroglial cells: relevance for multiple sclerosis and therapeutic strategies

(2014) Gayathri Sundaram et al.   Journal of Neuroinflammation

Quantitative Analyses of Schizophrenia-Associated Metabolites in Serum: Serum D-Lactate Levels Are Negatively Correlated with Gamma-Glutamylcysteine in Medicated Schizophrenia Patients

(2014) Takeshi Fukushima et al.   PLoS One

Neurodevelopmental and Neurodegenerative Models of Schizophrenia: White Matter at the Center Stage

(2014) P. Kochunov et al.   SCHIZOPHRENIA BULLETIN

Cytokine function in medication-naive first episode psychosis: A systematic review and meta-analysis

(2014) Rachel Upthegrove et al.   SCHIZOPHRENIA RESEARCH

Stress-Induced Increase in Kynurenic Acid as a Potential Biomarker for Patients With Schizophrenia and Distress Intolerance

(2014) Joshua Chiappelli et al.   JAMA Psychiatry

A snapshot of plasma metabolites in first-episode schizophrenia: a capillary electrophoresis time-of-flight mass spectrometry study

(2014) S Koike et al.   Translational Psychiatry

Tryptophan Catabolites from Microbiota Engage Aryl Hydrocarbon Receptor and Balance Mucosal Reactivity via Interleukin-22

(2013) Teresa Zelante et al.   IMMUNITY

Glutamatergic changes in the cerebral white matter associated with schizophrenic exacerbation

(2012) M. Ota et al.   ACTA PSYCHIATRICA SCANDINAVICA

Pre- and postnatal exposure to kynurenine causes cognitive deficits in adulthood

(2012) Ana Pocivavsek et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Kynurenines in the mammalian brain: when physiology meets pathology

(2012) Robert Schwarcz et al.   NATURE REVIEWS NEUROSCIENCE

White matter integrity, fiber count, and other fallacies: The do's and don'ts of diffusion MRI

(2012) Derek K. Jones et al.   NEUROIMAGE

Chronic Low-Grade Inflammation in Elderly Persons Is Associated with Altered Tryptophan and Tyrosine Metabolism: Role in Neuropsychiatric Symptoms

(2011) Lucile Capuron et al.   BIOLOGICAL PSYCHIATRY

Meta-Analysis of Cytokine Alterations in Schizophrenia: Clinical Status and Antipsychotic Effects

(2011) Brian J. Miller et al.   BIOLOGICAL PSYCHIATRY

Metabolomic Profiling to Identify Potential Serum Biomarkers for Schizophrenia and Risperidone Action

(2011) Jiekun Xuan et al.   JOURNAL OF PROTEOME RESEARCH

IL-23 modulated myelin-specific T cells induce EAE via an IFNγ driven, IL-17 independent pathway

(2010) Mark A. Kroenke et al.   BRAIN BEHAVIOR AND IMMUNITY

Fractional anisotropy of water diffusion in cerebral white matter across the lifespan

(2010) P. Kochunov et al.   NEUROBIOLOGY OF AGING

Cortical kynurenic acid bi-directionally modulates prefrontal glutamate levels as assessed by microdialysis and rapid electrochemistry

(2010) Å. Konradsson-Geuken et al.   NEUROSCIENCE

Decreased plasma tryptophan and tryptophan/large neutral amino acid ratio in patients with neuroleptic-resistant schizophrenia: Relationship to plasma cortisol concentration

(2010) Myung Lee et al.   PSYCHIATRY RESEARCH

Impaired Kynurenine Pathway Metabolism in The Prefrontal Cortex of Individuals With Schizophrenia

(2010) K. V. Sathyasaikumar et al.   SCHIZOPHRENIA BULLETIN

Increased Levels of Kynurenine and Kynurenic Acid in the CSF of Patients With Schizophrenia

(2010) K. R. Linderholm et al.   SCHIZOPHRENIA BULLETIN

The Astrocyte-Derived α7 Nicotinic Receptor Antagonist Kynurenic Acid Controls Extracellular Glutamate Levels in the Prefrontal Cortex

(2009) Hui-Qiu Wu et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Altered interactions of tryptophan metabolites in first-episode neuroleptic-naive patients with schizophrenia

(2009) J K Yao et al.   MOLECULAR PSYCHIATRY

Cytokine Changes and Tryptophan Metabolites in Medication-Naïve and Medication-Free Schizophrenic Patients

(2009) Yong-Ku Kim et al.   NEUROPSYCHOBIOLOGY

Meta-analysis of diffusion tensor imaging studies in schizophrenia

(2009) Ian Ellison-Wright et al.   SCHIZOPHRENIA RESEARCH

Kynurenine pathway in psychosis: evidence of increased tryptophan degradation

(2008) S Barry et al.   JOURNAL OF PSYCHOPHARMACOLOGY