Dysfunction of NMDA receptors in Alzheimer’s disease

Disturbed Neurotransmitter Transporter Expression in Alzheimer’s Disease Brain

(2016) Kevin H. Chen et al.   JOURNAL OF ALZHEIMERS DISEASE

Repetitive transcranial magnetic stimulation enhances spatial learning and synaptic plasticity via the VEGF and BDNF–NMDAR pathways in a rat model of vascular dementia

(2015) N. Zhang et al.   NEUROSCIENCE

Correction to Supporting Information for Talantova et al., Aβ induces astrocytic glutamate release, extrasynaptic NMDA receptor activation, and synaptic loss

(2015)   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Role of the Tripartite Glutamatergic Synapse in the Pathophysiology of Alzheimer’s Disease

(2015) Carolyn C. Rudy et al.   Aging and Disease

A Naturally Occurring Null Variant of the NMDA Type Glutamate Receptor NR3B Subunit Is a Risk Factor of Schizophrenia

(2015) Hitomi Matsuno et al.   PLoS One

Cognitive effects of repetitive transcranial magnetic stimulation in patients with neurodegenerative diseases — Clinician's perspective

(2014) Lubomira Anderkova et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Mechanism of Oxidative Stress and Synapse Dysfunction in the Pathogenesis of Alzheimer’s Disease: Understanding the Therapeutics Strategies

(2014) Pradip K. Kamat et al.   MOLECULAR NEUROBIOLOGY

Extrasynaptic NMDA Receptor Involvement in Central Nervous System Disorders

(2014) Matthew P. Parsons et al.   NEURON

Distinct Functional and Pharmacological Properties of Triheteromeric GluN1/GluN2A/GluN2B NMDA Receptors

(2014) Kasper B. Hansen et al.   NEURON

GLT-1 transporter: An effective pharmacological target for various neurological disorders

(2014) Neha Soni et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Organization, control and function of extrasynaptic NMDA receptors

(2014) T. Papouin et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Cyclophilin D deficiency rescues Aβ-impaired PKA/CREB signaling and alleviates synaptic degeneration

(2013) Heng Du et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Encoding and Transducing the Synaptic or Extrasynaptic Origin of NMDA Receptor Signals to the Nucleus

(2013) Anna Karpova et al.   CELL

Low-frequency (1Hz) repetitive transcranial magnetic stimulation (rTMS) reverses Aβ1–42-mediated memory deficits in rats

(2013) Tao Tan et al.   EXPERIMENTAL GERONTOLOGY

Dysfunctional synapse in Alzheimer's disease – A focus on NMDA receptors

(2013) Sandra I. Mota et al.   NEUROPHARMACOLOGY

Okadaic acid-induced Tau phosphorylation in rat brain: Role of NMDA receptor

(2013) P.K. Kamat et al.   NEUROSCIENCE

NMDA Reduces Tau Phosphorylation in Rat Hippocampal Slices by Targeting NR2A Receptors, GSK3β, and PKC Activities

(2013) Audrée De Montigny et al.   NEURAL PLASTICITY

Endoplasmic reticulum stress occurs downstream of GluN2B subunit ofN-methyl-D-aspartate receptor in mature hippocampal cultures treated with amyloid-β oligomers

(2012) Rui O. Costa et al.   AGING CELL

A Population-Specific Uncommon Variant in GRIN3A Associated with Schizophrenia

(2012) Atsushi Takata et al.   BIOLOGICAL PSYCHIATRY

Presynaptic NMDA receptors: Are they dendritic receptors in disguise?

(2012) Ian C. Duguid   BRAIN RESEARCH BULLETIN

Alzheimer's disease, β-amyloid, glutamate, NMDA receptors and memantine - searching for the connections

(2012) Wojciech Danysz et al.   BRITISH JOURNAL OF PHARMACOLOGY

Synaptic and Extrasynaptic NMDA Receptors Are Gated by Different Endogenous Coagonists

(2012) Thomas Papouin et al.   CELL

Interaction of Endogenous Tau Protein with Synaptic Proteins Is Regulated byN-Methyl-d-aspartate Receptor-dependent Tau Phosphorylation

(2012) Siddhartha Mondragón-Rodríguez et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Target-Specific Expression of Presynaptic NMDA Receptors in Neocortical Microcircuits

(2012) Katherine A. Buchanan et al.   NEURON

Diversity in NMDA Receptor Composition

(2012) Antonio Sanz-Clemente et al.   NEUROSCIENTIST

Amyloid beta peptide 1–42 disturbs intracellular calcium homeostasis through activation of GluN2B-containing N-methyl-d-aspartate receptors in cortical cultures

(2011) I.L. Ferreira et al.   CELL CALCIUM

A review of the effects of memantine on clinical progression in Alzheimer's disease

(2011) David Wilkinson   INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY

Amyloid β-Mediated Cell Death of Cultured Hippocampal Neurons Reveals Extensive Tau Fragmentation without Increased Full-length Tau Phosphorylation

(2011) Jack Reifert et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Soluble A  Oligomers Inhibit Long-Term Potentiation through a Mechanism Involving Excessive Activation of Extrasynaptic NR2B-Containing NMDA Receptors

(2011) S. Li et al.   JOURNAL OF NEUROSCIENCE

The role of CREB signaling in Alzheimer’s disease and other cognitive disorders

(2011) Carlos A. Saura et al.   REVIEWS IN THE NEUROSCIENCES

Regulation of Forkhead Transcription Factor FoxO3a Contributes to Calorie Restriction-induced Prevention of Alzheimer's Disease-type Amyloid Neuropathology and Spatial Memory Deterioration

(2010) Weiping Qin et al.   Annals of the New York Academy of Sciences

Dendritic Function of Tau Mediates Amyloid-β Toxicity in Alzheimer's Disease Mouse Models

(2010) Lars M. Ittner et al.   CELL

Synaptic Activity and Nuclear Calcium Signaling Protect Hippocampal Neurons from Death Signal-associated Nuclear Translocation of FoxO3a Induced by ExtrasynapticN-Methyl-d-aspartate Receptors

(2010) Oliver Dick et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Long-term potentiation depends on release of d-serine from astrocytes

(2010) Christian Henneberger et al.   NATURE

Mutations in GRIN2A and GRIN2B encoding regulatory subunits of NMDA receptors cause variable neurodevelopmental phenotypes

(2010) Sabine Endele et al.   NATURE GENETICS

Synaptic versus extrasynaptic NMDA receptor signalling: implications for neurodegenerative disorders

(2010) Giles E. Hardingham et al.   NATURE REVIEWS NEUROSCIENCE

Early neuronal dysfunction by amyloid β oligomers depends on activation of NR2B-containing NMDA receptors

(2010) Raik Rönicke et al.   NEUROBIOLOGY OF AGING

Tau Mislocalization to Dendritic Spines Mediates Synaptic Dysfunction Independently of Neurodegeneration

(2010) Brian R. Hoover et al.   NEURON

Organization of NMDA receptors at extrasynaptic locations

(2010) R.S. Petralia et al.   NEUROSCIENCE

Memantine Improves Cognition and Reduces Alzheimer’s-Like Neuropathology in Transgenic Mice

(2009) Hilda Martinez-Coria et al.   AMERICAN JOURNAL OF PATHOLOGY

Genetic Variation in N-Methyl-D-Aspartate Receptor Subunit NR3A but Not NR3B Influences Susceptibility to Alzheimer’s Disease

(2009) Hsin-Ping Liu et al.   DEMENTIA AND GERIATRIC COGNITIVE DISORDERS

Synaptic NMDA Receptor Activation Stimulates  -Secretase Amyloid Precursor Protein Processing and Inhibits Amyloid-  Production

(2009) S. E. Hoey et al.   JOURNAL OF NEUROSCIENCE

Extrasynaptic NMDA Receptors Couple Preferentially to Excitotoxicity via Calpain-Mediated Cleavage of STEP

(2009) J. Xu et al.   JOURNAL OF NEUROSCIENCE

Mg2+ Imparts NMDA Receptor Subtype Selectivity to the Alzheimer's Drug Memantine

(2009) S. E. Kotermanski et al.   JOURNAL OF NEUROSCIENCE

Both NR2A and NR2B subunits of the NMDA receptor are critical for long-term potentiation and long-term depression in the lateral amygdala of horizontal slices of adult mice

(2009) T. Muller et al.   LEARNING & MEMORY

Transcription Factors in Long-Term Memory and Synaptic Plasticity

(2009) Cristina M. Alberini   PHYSIOLOGICAL REVIEWS

GluN2B subunit-containing NMDA receptor antagonists prevent A -mediated synaptic plasticity disruption in vivo

(2009) N.-W. Hu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Spine microdomains for postsynaptic signaling and plasticity

(2009) Thomas M. Newpher et al.   TRENDS IN CELL BIOLOGY

Neramexane: a moderate-affinity NMDA receptor channel blocker: new prospects and indications

(2009) Gerhard Rammes   Expert Review of Clinical Pharmacology

Developmental Regulation of the NMDA Receptor Subunits, NR3A and NR1, in Human Prefrontal Cortex

(2008) Maile A. Henson et al.   CEREBRAL CORTEX

Memantine protects rat cortical cultured neurons against β-amyloid-induced toxicity by attenuating tau phosphorylation

(2008) M. S. Song et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Presynaptic NMDA Receptors: Newly Appreciated Roles in Cortical Synaptic Function and Plasticity

(2008) Rebekah Corlew et al.   NEUROSCIENTIST

Neuronal calcium mishandling and the pathogenesis of Alzheimer's disease

(2008) Ilya Bezprozvanny et al.   TRENDS IN NEUROSCIENCES

Caldendrin–Jacob: A Protein Liaison That Couples NMDA Receptor Signalling to the Nucleus

(2008) Daniela C Dieterich et al.   PLOS BIOLOGY

Amyloid beta peptides and glutamatergic synaptic dysregulation

(2007) Kodeeswaran Parameshwaran et al.   EXPERIMENTAL NEUROLOGY

Calcium influx through N-methyl-d-aspartate receptors triggers GABA release at interneuron–Purkinje cell synapse in rat cerebellum

(2007) M.D. Glitsch   NEUROSCIENCE