Ursolic Acid Ameliorates Early Brain Injury After Experimental Traumatic Brain Injury in Mice by Activating the Nrf2 Pathway

Neferine prevents autophagy induced by hypoxia through activation of Akt/mTOR pathway and Nrf2 in muscle cells

(2016) Rathinasamy Baskaran et al.   BIOMEDICINE & PHARMACOTHERAPY

Activation of AKT pathway by Nrf2/PDGFA feedback loop contributes to HCC progression

(2016) Danyang Liu et al.   Oncotarget

Effect of glycosides based standardized fenugreek seed extract in bleomycin-induced pulmonary fibrosis in rats: Decisive role of Bax, Nrf2, NF-κB, Muc5ac, TNF-α and IL-1β

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Alpha lipoic acid inhibits neural apoptosis via a mitochondrial pathway in rats following traumatic brain injury

(2015) Wuting Wei et al.   NEUROCHEMISTRY INTERNATIONAL

Protective effects of ursolic acid in an experimental model of liver fibrosis through Nrf2/ARE pathway

(2015) Jie-Qiong Ma et al.   Clinics and Research in Hepatology and Gastroenterology

Oxidative Stress in Traumatic Brain Injury

(2014) Ana Rodriguez-Rodriguez et al.   CURRENT MEDICINAL CHEMISTRY

Luteolin provides neuroprotection in models of traumatic brain injury via the Nrf2–ARE pathway

(2014) Jianguo Xu et al.   FREE RADICAL BIOLOGY AND MEDICINE

Melatonin stimulates antioxidant enzymes and reduces oxidative stress in experimental traumatic brain injury: the Nrf2–ARE signaling pathway as a potential mechanism

(2014) Ke Ding et al.   FREE RADICAL BIOLOGY AND MEDICINE

Ursolic acid alleviates early brain injury after experimental subarachnoid hemorrhage by suppressing TLR4-mediated inflammatory pathway

(2014) Tingting Zhang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Ursolic acid prevents endoplasmic reticulum stress-mediated apoptosis induced by heat stress in mouse cardiac myocytes

(2014) Ying Yang et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Temporal and Spatial Dynamics of Nrf2-Antioxidant Response Elements Mediated Gene Targets in Cortex and Hippocampus after Controlled Cortical Impact Traumatic Brain Injury in Mice

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Traumatic Brain Injury: Oxidative Stress and Neuroprotection

(2013) Carolin Cornelius et al.   ANTIOXIDANTS & REDOX SIGNALING

Oxidative stress, DNA damage, and the telomeric complex as therapeutic targets in acute neurodegeneration

(2013) Joshua A. Smith et al.   NEUROCHEMISTRY INTERNATIONAL

Pseudomonas aeruginosa Pyocyanin Activates NRF2-ARE-Mediated Transcriptional Response via the ROS-EGFR-PI3K-AKT/MEK-ERK MAP Kinase Signaling in Pulmonary Epithelial Cells

(2013) Ying Xu et al.   PLoS One

Ursolic acid promotes the neuroprotection by activating Nrf2 pathway after cerebral ischemia in mice

(2012) Litao Li et al.   BRAIN RESEARCH

Hydrogen-rich saline protects against oxidative damage and cognitive deficits after mild traumatic brain injury

(2012) Zonggang Hou et al.   BRAIN RESEARCH BULLETIN

Ursolic Acid Inhibits Cigarette Smoke Extract-Induced Human Bronchial Epithelial Cell Injury and Prevents Development of Lung Cancer

(2012) Wenbo Liu et al.   MOLECULES

Emerging roles of Nrf2 and phase II antioxidant enzymes in neuroprotection

(2012) Meijuan Zhang et al.   PROGRESS IN NEUROBIOLOGY

Reactive oxygen species and PI3K/Akt signaling play key roles in the induction of Nrf2-driven heme oxygenase-1 expression in sulforaphane-treated human mesothelioma MSTO-211H cells

(2011) Yoon-Jin Lee et al.   FOOD AND CHEMICAL TOXICOLOGY

Histone deacetylase inhibition activates transcription factor Nrf2 and protects against cerebral ischemic damage

(2011) Bing Wang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Mouse closed head injury model induced by a weight-drop device

(2009) Michael A Flierl et al.   Nature Protocols

The Expression of NF-E2-Related Factor 2 in the Rat Brain After Traumatic Brain Injury

(2009) Wei Yan et al.   JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE

Targeting the PI3K–AKT–mTOR pathway: progress, pitfalls, and promises

(2008) Timothy A Yap et al.   CURRENT OPINION IN PHARMACOLOGY

Nrf2-induced antioxidant protection: A promising target to counteract ROS-mediated damage in neurodegenerative disease?

(2008) Helga E. de Vries et al.   FREE RADICAL BIOLOGY AND MEDICINE

A Time Course of Contusion-Induced Oxidative Stress and Synaptic Proteins in Cortex in a Rat Model of TBI

(2008) Mubeen A. Ansari et al.   JOURNAL OF NEUROTRAUMA

Moderate and severe traumatic brain injury in adults

(2008) Andrew IR Maas et al.   LANCET NEUROLOGY