Multicomponent Reactions, Union of MCRs and Beyond

Ugi and Passerini Reactions of Biocatalytically Derived Chiral Aldehydes: Application to the Synthesis of Bicyclic Pyrrolidines and of Antiviral Agent Telaprevir

(2015) Lisa Moni et al.   JOURNAL OF ORGANIC CHEMISTRY

Discovery of Highly Potent p53-MDM2 Antagonists and Structural Basis for Anti-Acute Myeloid Leukemia Activities

(2014) Yijun Huang et al.   ACS Chemical Biology

Concise Synthesis of Tetrazole-Ketopiperazines by Two Consecutive Ugi Reactions

(2014) Tryfon Zarganes-Tzitzikas et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

The Ugi-Smiles and Passerini-Smiles Couplings: A Story About Phenols in Isocyanide-Based Multicomponent Reactions

(2014) Laurent El Kaïm et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Modern multicomponent reactions for better drug syntheses

(2014) Tryfon Zarganes-Tzitzikas et al.   Organic Chemistry Frontiers

Multicomponent Reactions in Polymer Synthesis

(2013) Ryohei Kakuchi   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Sequence Control in Polymer Chemistry through the Passerini Three-Component Reaction

(2013) Susanne C. Solleder et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Tricycles by a New Ugi Variation and Pictet-Spengler Reaction in One Pot

(2013) Mantosh K. Sinha et al.   CHEMISTRY-A EUROPEAN JOURNAL

Multicomponent Reactions for de Novo Synthesis of BODIPY Probes: In Vivo Imaging of Phagocytic Macrophages

(2013) Ana Vázquez-Romero et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Various cyclization scaffolds by a truly Ugi 4-CR

(2013) Mantosh K. Sinha et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Transient Protein States in Designing Inhibitors of the MDM2-p53 Interaction

(2013) Michal Bista et al.   STRUCTURE

Efficient Assembly of Iminodicarboxamides by a “Truly” Four-Component Reaction

(2012) Kareem Khoury et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chemistry and Biology Of Multicomponent Reactions

(2012) Alexander Dömling et al.   CHEMICAL REVIEWS

Multicomponent Reaction Design in the Quest for Molecular Complexity and Diversity

(2011) Eelco Ruijter et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Exhaustive Fluorine Scanning toward Potent p53-Mdm2 Antagonists

(2011) Yijun Huang et al.   ChemMedChem

Combinatorial Discovery of Fluorescent Pharmacophores by Multicomponent Reactions in Droplet Arrays

(2011) Olga N. Burchak et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Total Synthesis and Biological Evaluation of Pederin, Psymberin, and Highly Potent Analogs

(2011) Shuangyi Wan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Robust Generation of Lead Compounds for Protein-Protein Interactions by Computational and MCR Chemistry: p53/Hdm2 Antagonists

(2010) Anna Czarna et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synchronized Synthesis of Peptide-Based Macrocycles by Digital Microfluidics

(2010) Mais J. Jebrail et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A highly efficient synthesis of telaprevir by strategic use of biocatalysis and multicomponent reactions

(2010) Anass Znabet et al.   CHEMICAL COMMUNICATIONS

Efficient Multicomponent Reaction Synthesis of the Schistosomiasis Drug Praziquantel

(2010) Haiping Cao et al.   CHEMISTRY-A EUROPEAN JOURNAL

Rapid Assembly of Polyfunctional Structures Using a One-Pot Five- and Six-Component Sequential Groebke-Blackburn/Ugi/Passerini Process

(2010) Taleb H. Al-Tel et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Total Syntheses of (−)-Fructigenine A and (−)-5-N-Acetylardeemin

(2010) Satoshi Takiguchi et al.   JOURNAL OF ORGANIC CHEMISTRY

Macrocyclization of Linear Peptides Enabled by Amphoteric Molecules

(2010) Ryan Hili et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The Efficient One-Pot Reaction of up to Eight Components by the Union of Multicomponent Reactions

(2009) Niels Elders et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Natural Product Synthesis Using Multicomponent Reaction Strategies

(2009) Barry B. Touré et al.   CHEMICAL REVIEWS

A Multicomponent Reaction TowardsN-(Cyanomethyl)amides

(2009) Niels Elders et al.   CHEMISTRY-A EUROPEAN JOURNAL

Affinity ligands for immunoglobulins based on the multicomponent Ugi reaction

(2009) Jonathan M. Haigh et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Cyanoacetamide MCR (III): Three-Component Gewald Reactions Revisited

(2009) Kan Wang et al.   JOURNAL OF COMBINATORIAL CHEMISTRY

Ugi-Post Functionalization, from a Single Set of Ugi-Adducts to Two Distinct Heterocycles by Microwave-Assisted Palladium-Catalyzed Cyclizations: Tuning the Reaction Pathways by Ligand Switch

(2009) William Erb et al.   JOURNAL OF ORGANIC CHEMISTRY

(−)-Bacillamide C: the convergent approach

(2009) Wei Wang et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Design of a Bisamidinium Claisen Rearrangement Catalyst for Monodentate Substrates

(2009) Venkatachalam R. Annamalai et al.   ORGANIC LETTERS

Synthesis of Prostaglandin and Phytoprostane B1Via Regioselective Intermolecular Pauson−Khand Reactions†

(2009) Ana Vázquez-Romero et al.   ORGANIC LETTERS

Selective Formation of 2-Imidazolines and 2-Substituted Oxazoles by Using a Three-Component Reaction

(2008) Niels Elders et al.   CHEMISTRY-A EUROPEAN JOURNAL

New Chemistry with Old Functional Groups: On the Reaction of Isonitriles with Carboxylic Acids—A Route to Various Amide Types

(2008) Xuechen Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Multicomponent reactions in fungicide research: The discovery of mandipropamid

(2007) Clemens Lamberth et al.   BIOORGANIC & MEDICINAL CHEMISTRY