Hedgehog Gli signalling in kidney fibrosis

Perivascular Gli1+ Progenitors Are Key Contributors to Injury-Induced Organ Fibrosis

(2015) Rafael Kramann et al.   Cell Stem Cell

Pharmacological GLI2 inhibition prevents myofibroblast cell-cycle progression and reduces kidney fibrosis

(2015) Rafael Kramann et al.   JOURNAL OF CLINICAL INVESTIGATION

The suture provides a niche for mesenchymal stem cells of craniofacial bones

(2015) Hu Zhao et al.   NATURE CELL BIOLOGY

How much can the tubule regenerate and who does it? An open question

(2015) Duccio Lombardi et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Targeting the Hedgehog–Glioma-Associated Oncogene Homolog Pathway Inhibits Bleomycin-Induced Lung Fibrosis in Mice

(2014) Elika Farrokhi Moshai et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Secretion of Shh by a Neurovascular Bundle Niche Supports Mesenchymal Stem Cell Homeostasis in the Adult Mouse Incisor

(2014) Hu Zhao et al.   Cell Stem Cell

Sonic Hedgehog Is a Novel Tubule-Derived Growth Factor for Interstitial Fibroblasts after Kidney Injury

(2014) D. Zhou et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Who regenerates the kidney tubule?

(2014) R. Kramann et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Context-dependent signal integration by the GLI code: The oncogenic load, pathways, modifiers and implications for cancer therapy

(2014) Fritz Aberger et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Reactivation of NCAM1 Defines a Subpopulation of Human Adult Kidney Epithelial Cells with Clonogenic and Stem/Progenitor Properties

(2013) Ella Buzhor et al.   AMERICAN JOURNAL OF PATHOLOGY

Natural history of mesenchymal stem cells, from vessel walls to culture vessels

(2013) Iain R. Murray et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Identification of human nephron progenitors capable of generation of kidney structures and functional repair of chronic renal disease

(2013) Orit Harari-Steinberg et al.   EMBO Molecular Medicine

Understanding the origin, activation and regulation of matrix-producing myofibroblasts for treatment of fibrotic disease

(2013) Rafael Kramann et al.   JOURNAL OF PATHOLOGY

Unraveling the therapeutic potential of the Hedgehog pathway in cancer

(2013) Dereck Amakye et al.   NATURE MEDICINE

The mechanisms of Hedgehog signalling and its roles in development and disease

(2013) James Briscoe et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Hedgehog-Gli Pathway Activation during Kidney Fibrosis

(2012) Steven L. Fabian et al.   AMERICAN JOURNAL OF PATHOLOGY

Darinaparsin: Solid Tumor Hypoxic Cytotoxin and Radiosensitizer

(2012) J. Tian et al.   CLINICAL CANCER RESEARCH

Sonic Hedgehog Signaling Mediates Epithelial-Mesenchymal Communication and Promotes Renal Fibrosis

(2012) H. Ding et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The Hedgehog Signal Transduction Network

(2012) D. J. Robbins et al.   Science Signaling

What's Past Is Prologue: Developmental Pathways and Chronic Allograft Dysfunction

(2011) S. L. Fabian et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Gli Proteins in Development and Disease

(2011) Chi-chung Hui et al.   Annual Review of Cell and Developmental Biology

Hedgehog signaling pathway as a therapeutic target in various types of cancer

(2011) Hideya Onishi et al.   CANCER SCIENCE

The MSC: An Injury Drugstore

(2011) Arnold I. Caplan et al.   Cell Stem Cell

Hedgehog/Wnt feedback supports regenerative proliferation of epithelial stem cells in bladder

(2011) Kunyoo Shin et al.   NATURE

Sonic Hedgehog Signaling Induces Vascular Smooth Muscle Cell Proliferation via Induction of the G 1 Cyclin-Retinoblastoma Axis

(2010) Fenghe Li et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

The role of Hedgehog signaling in fibrogenic liver repair

(2010) Steve S. Choi et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Control of mammalian kidney development by the Hedgehog signaling pathway

(2010) Jason E. Cain et al.   PEDIATRIC NEPHROLOGY

Arsenic antagonizes the Hedgehog pathway by preventing ciliary accumulation and reducing stability of the Gli2 transcriptional effector

(2010) J. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Context-dependent Regulation of the GLI Code in Cancer by HEDGEHOG and Non-HEDGEHOG Signals

(2010) B. Stecca et al.   Journal of Molecular Cell Biology

Epidermal Growth Factor Receptor Signaling Synergizes with Hedgehog/GLI in Oncogenic Transformation via Activation of the MEK/ERK/JUN Pathway

(2009) Harald Schnidar et al.   CANCER RESEARCH

Hedgehog signalling: Emerging evidence for non-canonical pathways

(2009) Dagan Jenkins   CELLULAR SIGNALLING

A Phase I Clinical Trial of Darinaparsin in Patients with Refractory Solid Tumors

(2009) A. M. Tsimberidou et al.   CLINICAL CANCER RESEARCH

Darinaparsin: a novel organic arsenical with promising anticancer activity

(2009) Koren K Mann et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Cloning of the HumanGLI2Promoter

(2009) Sylviane Dennler et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Isolation and Characterization of Resident Mesenchymal Stem Cells in Human Glomeruli

(2009) Stefania Bruno et al.   STEM CELLS AND DEVELOPMENT

A Perivascular Origin for Mesenchymal Stem Cells in Multiple Human Organs

(2008) Mihaela Crisan et al.   Cell Stem Cell

A paracrine requirement for hedgehog signalling in cancer

(2008) Robert L. Yauch et al.   NATURE