Tempol and perindopril protect against lipopolysaccharide-induced cognition impairment and amyloidogenesis by modulating brain-derived neurotropic factor, neuroinflammation and oxido-nitrosative stress

Three-Dimensional Tomographic Imaging and Characterization of Iron Compounds within Alzheimer's Plaque Core Material

(2017) Joanna F. Collingwood et al.   JOURNAL OF ALZHEIMERS DISEASE

Tempol prevents chronic sleep-deprivation induced memory impairment

(2016) Karem H. Alzoubi et al.   BRAIN RESEARCH BULLETIN

TNF-alpha G308A Polymorphism and the Susceptibility to Alzheimer's Disease: An Updated Meta-analysis

(2015) Tengfei Wang   ARCHIVES OF MEDICAL RESEARCH

Oxidative stress involving changes in Nrf2 and ER stress in early stages of Alzheimer's disease

(2015) Sandra I. Mota et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Long-term treadmill exercise improves spatial memory of male appswe/ps1de9 mice by regulation of bdnf expression and microglia activation

(2015) Jingyu Xiong et al.   BIOLOGY OF SPORT

Experimental immunology The effects of EGb761 on lipopolysaccharide-induced depressive-like behaviour in C57BL/6J mice

(2015) Yuehan Zhao et al.   Central European Journal of Immunology

Therapeutic Approaches to Modulating Glutathione Levels as a Pharmacological Strategy in Alzheimer’s Disease

(2015) Nady Braidy et al.   Current Alzheimer Research

Oxidant/Antioxidant Imbalance and the Risk of Alzheimer's Disease

(2015) Ahmed Moneim   Current Alzheimer Research

Control of Energy Balance by the Brain Renin-Angiotensin System

(2015) Kristin E. Claflin et al.   CURRENT HYPERTENSION REPORTS

Ramipril and haloperidol as promising approaches in managing rheumatoid arthritis in rats

(2015) Mariam Gamal Fahmy Wahba et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Antioxidative effects of ethyl 2-(3-(benzo[d]thiazol-2-yl)ureido)acetate against amyloid β-induced oxidative cell death via NF-κB, GSK-3β and β-catenin signaling pathways in cultured cortical neurons

(2015) E.-A. Kim et al.   FREE RADICAL RESEARCH

Mitogen-activated protein kinase signaling pathways promote low-density lipoprotein receptor-related protein 1-mediated internalization of beta-amyloid protein in primary cortical neurons

(2015) Wei-Na Yang et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

FLZ attenuates learning and memory deficits via suppressing neuroinflammation induced by LPS in mice

(2015) Liang-Yu Wu et al.   JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH

Efficacy of the superoxide dismutase mimetic tempol in animal hypertension models

(2015) Waleska C. Dornas et al.   JOURNAL OF HYPERTENSION

Deferoxamine attenuates lipopolysaccharide-induced neuroinflammation and memory impairment in mice

(2015) Xiao-Ying Zhang et al.   Journal of Neuroinflammation

Oxidative stress and lipid peroxidation are upstream of amyloid pathology

(2015) Muriel Arimon et al.   NEUROBIOLOGY OF DISEASE

Reactive oxygen species mediate cognitive deficits in experimental temporal lobe epilepsy

(2015) Jennifer N. Pearson et al.   NEUROBIOLOGY OF DISEASE

Intermittent Hypoxia-Induced Parvalbumin-Immunoreactive Interneurons Loss and Neurobehavioral Impairment is Mediated by NADPH-Oxidase-2

(2015) Liang Yuan et al.   NEUROCHEMICAL RESEARCH

Resveratrol Protects Hippocampal Astrocytes Against LPS-Induced Neurotoxicity Through HO-1, p38 and ERK Pathways

(2015) Bruna Bellaver et al.   NEUROCHEMICAL RESEARCH

Gracilins: Spongionella-derived promising compounds for Alzheimer disease

(2015) Marta Leirós et al.   NEUROPHARMACOLOGY

Harpagoside ameliorates the amyloid-β-induced cognitive impairment in rats via up-regulating BDNF expression and MAPK/PI3K pathways

(2015) J. Li et al.   NEUROSCIENCE

The potential effect of the angiotensin II receptor blocker telmisartan in regulating OVA-induced airway remodeling in experimental rats

(2015) Maha M. Abdel-Fattah et al.   Pharmacological Reports

Zinc Prevents Sickness Behavior Induced by Lipopolysaccharides after a Stress Challenge in Rats

(2015) Thiago B. Kirsten et al.   PLoS One

Contribution of reactive oxygen species to cerebral amyloid angiopathy, vasomotor dysfunction, and microhemorrhage in aged Tg2576 mice

(2015) Byung Hee Han et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The relationship between brain-derived neurotrophic factor levels, oxidative and nitrosative stress and depressive symptoms: a study on peritoneal dialysis

(2015) Fatma Ceyla Eraldemir et al.   RENAL FAILURE

Oxidized cholesterol as the driving force behind the development of Alzheimer’s disease

(2015) Paola Gamba et al.   Frontiers in Aging Neuroscience

Impact of an additional chronic BDNF reduction on learning performance in an Alzheimer mouse model

(2015) Laura Psotta et al.   Frontiers in Behavioral Neuroscience

Brain plasticity and cognitive functions after ethanol consumption in C57BL/6J mice

(2015) E Stragier et al.   Translational Psychiatry

EFFECT OF TEMPOL ON REDOX HOMEOSTASIS AND STRESS TOLERANCE IN MIMETICALLY AGEDDROSOPHILA

(2014) Ugur Aksu et al.   ARCHIVES OF INSECT BIOCHEMISTRY AND PHYSIOLOGY

Impaired cognition in depression and Alzheimer (AD): a gradient from depression to depression in AD

(2014) Narahyana Bom de Araujo et al.   ARQUIVOS DE NEURO-PSIQUIATRIA

Neutralization of TNFSF10 ameliorates functional outcome in a murine model of Alzheimer’s disease

(2014) Giuseppina Cantarella et al.   BRAIN

Protective effects of perindopril on d-galactose and aluminum trichloride induced neurotoxicity via the apoptosis of mitochondria-mediated intrinsic pathway in the hippocampus of mice

(2014) Weina Yang et al.   BRAIN RESEARCH BULLETIN

Overexpression of NMDAR2B in an inflammatory model of Alzheimer's disease: Modulation by NOS inhibitors

(2014) Ahmed Maher et al.   BRAIN RESEARCH BULLETIN

Medial temporal lobe atrophy in Alzheimer's disease/mild cognitive impairment with depression

(2014) V Dhikav et al.   BRITISH JOURNAL OF RADIOLOGY

The neuroprotective properties of the superoxide dismutase mimetic tempol correlate with its ability to reduce pathological glutamate release in a rodent model of stroke

(2014) Preeti Dohare et al.   FREE RADICAL BIOLOGY AND MEDICINE

Antioxidant effect of imperatorin from Angelica dahurica in hypertension via inhibiting NADPH oxidase activation and MAPK pathway

(2014) Yanjun Cao et al.   Journal of the American Society of Hypertension

Aminoguanidine treatment ameliorates inflammatory responses and memory impairment induced by amyloid-beta 25–35 injection in rats

(2014) Alfonso Díaz et al.   NEUROPEPTIDES

Aβ and tau toxicities in Alzheimer’s are linked via oxidative stress-induced p38 activation: Protective role of vitamin E

(2014) E. Giraldo et al.   Redox Biology

The global prevalence of dementia: A systematic review and metaanalysis

(2013) Martin Prince et al.   Alzheimers & Dementia

Vascular Aspects of Cognitive Impairment and Dementia

(2013) Maximilian Wiesmann et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Amyloid-β Inhibits Thrombospondin 1 Release From Cultured Astrocytes: Effects on Synaptic Protein Expression

(2013) Kakulavarapu V. Rama Rao et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Object recognition test in mice

(2013) Marianne Leger et al.   Nature Protocols

Microglial derived tumor necrosis factor-α drives Alzheimer's disease-related neuronal cell cycle events

(2013) Kiran Bhaskar et al.   NEUROBIOLOGY OF DISEASE

Nitro-Oxidative Stress after Neuronal Ischemia Induces Protein Nitrotyrosination and Cell Death

(2013) Marta Tajes et al.   Oxidative Medicine and Cellular Longevity

The effects of perindopril on cognitive impairment induced by d-galactose and aluminum trichloride via inhibition of acetylcholinesterase activity and oxidative stress

(2013) Wei-Na Yang et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

The cerebellum: a new key structure in the navigation system

(2013) Christelle Rochefort et al.   Frontiers in Neural Circuits

Modification of γ-secretase by nitrosative stress links neuronal ageing to sporadic Alzheimer's disease

(2012) Francesc X. Guix et al.   EMBO Molecular Medicine

NADPH Oxidase-Derived Reactive Oxygen Species Are Involved in the HL-60 Cell Monocytic Differentiation Induced by Isoliquiritigenin

(2012) Hongmei Chen et al.   MOLECULES

Brain-Derived Neurotrophic Factor Ameliorates Brain Stem Cardiovascular Dysregulation during Experimental Temporal Lobe Status Epilepticus

(2012) Ching-Yi Tsai et al.   PLoS One

Critical Role of NADPH Oxidase in Neuronal Oxidative Damage and Microglia Activation following Traumatic Brain Injury

(2012) Quan-Guang Zhang et al.   PLoS One

Perindopril, a centrally active angiotensin-converting enzyme inhibitor, prevents cognitive impairment in mouse models of Alzheimer's disease

(2011) Yi-Fei Dong et al.   FASEB JOURNAL

Opposing Synaptic Regulation of Amyloid-  Metabolism by NMDA Receptors In Vivo

(2011) D. K. Verges et al.   JOURNAL OF NEUROSCIENCE

Central Angiotensin II Stimulation Promotes β Amyloid Production in Sprague Dawley Rats

(2011) Donglin Zhu et al.   PLoS One

Effect of a centrally active angiotensin-converting enzyme inhibitor, perindopril, on cognitive performance in a mouse model of Alzheimer's disease

(2010) Koji Yamada et al.   BRAIN RESEARCH

Angiotensin II blockade: a strategy to slow ageing by protecting mitochondria?

(2010) E. M. V. de Cavanagh et al.   CARDIOVASCULAR RESEARCH

Angiotensin II revisited: new roles in inflammation, immunology and aging

(2010) Ariela Benigni et al.   EMBO Molecular Medicine

Nonhypotensive Dose of Telmisartan Attenuates Cognitive Impairment Partially Due to Peroxisome Proliferator-Activated Receptor-γ Activation in Mice With Chronic Cerebral Hypoperfusion

(2010) Kazuo Washida et al.   STROKE

Lipopolysaccharide alters the blood–brain barrier transport of amyloid β protein: A mechanism for inflammation in the progression of Alzheimer’s disease

(2009) Laura B. Jaeger et al.   BRAIN BEHAVIOR AND IMMUNITY

Tumor necrosis factor alpha (TNF-α) levels in the brain and cerebrospinal fluid after meningitis induced by Streptococcus pneumoniae

(2009) Tatiana Barichello et al.   NEUROSCIENCE LETTERS

Possible involvement of NO/NOS signaling in hippocampal amyloid-β production induced by transient focal cerebral ischemia in aged rats

(2009) Song Li et al.   NEUROSCIENCE LETTERS

Chemistry and Antihypertensive Effects of Tempol and Other Nitroxides

(2008) C. S. Wilcox et al.   PHARMACOLOGICAL REVIEWS

Role of the renin–angiotensin system in vascular inflammation

(2008) Chiara Marchesi et al.   TRENDS IN PHARMACOLOGICAL SCIENCES