Neurotrophic factor control of satiety and body weight

Discrete BDNF Neurons in the Paraventricular Hypothalamus Control Feeding and Energy Expenditure

(2015) Juan Ji An et al.   Cell Metabolism

A neural basis for melanocortin-4 receptor–regulated appetite

(2015) Alastair S Garfield et al.   NATURE NEUROSCIENCE

Cognitive and autonomic determinants of energy homeostasis in obesity

(2015) Denis Richard   Nature Reviews Endocrinology

Ablation of intact hypothalamic and/or hindbrain TrkB signaling leads to perturbations in energy balance

(2015) Ceren Ozek et al.   Molecular Metabolism

Brain-derived neurotrophic factor is required for axonal growth of selective groups of neurons in the arcuate nucleus

(2015) Guey-Ying Liao et al.   Molecular Metabolism

Function and Dysfunction of Hypocretin/Orexin: An Energetics Point of View

(2014) Xiao-Bing Gao et al.   Annual Review of Neuroscience

20 YEARS OF LEPTIN: Leptin at 20: an overview

(2014) Jeffrey Friedman   JOURNAL OF ENDOCRINOLOGY

Hypothalamic Dysfunction of the Thrombospondin Receptor  2 -1 Underlies the Overeating and Obesity Triggered by Brain-Derived Neurotrophic Factor Deficiency

(2014) J. W. Cordeira et al.   JOURNAL OF NEUROSCIENCE

MC4R-expressing glutamatergic neurons in the paraventricular hypothalamus regulate feeding and are synaptically connected to the parabrachial nucleus

(2014) B. P. Shah et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Parallel, Redundant Circuit Organization for Homeostatic Control of Feeding Behavior

(2013) J. Nicholas Betley et al.   CELL

Glutamate Mediates the Function of Melanocortin Receptor 4 on Sim1 Neurons in Body Weight Regulation

(2013) Yuanzhong Xu et al.   Cell Metabolism

Adaptive thermogenesis in adipocytes: Is beige the new brown?

(2013) J. Wu et al.   GENES & DEVELOPMENT

Neuronal circuits that regulate feeding behavior and metabolism

(2013) Jong-Woo Sohn et al.   TRENDS IN NEUROSCIENCES

Pharmacological strategies for targeting BAT thermogenesis

(2013) Andrew Whittle et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Ablation of TrkB expression in RGS9-2 cells leads to hyperphagic obesity

(2013) Guey-Ying Liao et al.   Molecular Metabolism

Energy balance and its components: implications for body weight regulation

(2012) Kevin D. Hall et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Adult obesity susceptibility variants are associated with greater childhood weight gain and a faster tempo of growth: the 1946 British Birth Cohort Study

(2012) Cathy E Elks et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

TrkB receptor signaling in the nucleus tractus solitarius mediates the food intake-suppressive effects of hindbrain BDNF and leptin

(2012) Andrea M. Spaeth et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

GABAergic RIP-Cre Neurons in the Arcuate Nucleus Selectively Regulate Energy Expenditure

(2012) Dong Kong et al.   CELL

The Anorectic Effect of CNTF Does Not Require Action in Leptin-Responsive Neurons

(2012) M. A. Stefater et al.   ENDOCRINOLOGY

Effects of aging and caloric restriction on brainstem satiety center signals in rats

(2012) Emmanuel Moyse et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Common variants at CDKAL1 and KLF9 are associated with body mass index in east Asian populations

(2012) Yukinori Okada et al.   NATURE GENETICS

Meta-analysis identifies common variants associated with body mass index in east Asians

(2012) Wanqing Wen et al.   NATURE GENETICS

Dendritically targeted Bdnf mRNA is essential for energy balance and response to leptin

(2012) Guey-Ying Liao et al.   NATURE MEDICINE

Leptin action through hypothalamic nitric oxide synthase-1–expressing neurons controls energy balance

(2012) Rebecca L Leshan et al.   NATURE MEDICINE

From neuroanatomy to behavior: central integration of peripheral signals regulating feeding behavior

(2012) Kevin W Williams et al.   NATURE NEUROSCIENCE

Neurotrophin regulation of neural circuit development and function

(2012) Hyungju Park et al.   NATURE REVIEWS NEUROSCIENCE

Fasting Activation of AgRP Neurons Requires NMDA Receptors and Involves Spinogenesis and Increased Excitatory Tone

(2012) Tiemin Liu et al.   NEURON

Central Control of Brown Adipose Tissue Thermogenesis

(2012) Shaun F. Morrison et al.   Frontiers in Endocrinology

The anorexigenic cytokine ciliary neurotrophic factor stimulates POMC gene expression via receptors localized in the nucleus of arcuate neurons

(2011) Odile Couvreur et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

White to Brown Fat Phenotypic Switch Induced by Genetic and Environmental Activation of a Hypothalamic-Adipocyte Axis

(2011) Lei Cao et al.   Cell Metabolism

Melanocortin-4 Receptors Expressed by Cholinergic Neurons Regulate Energy Balance and Glucose Homeostasis

(2011) Jari Rossi et al.   Cell Metabolism

Modulation of the central melanocortin system by leptin, insulin, and serotonin: Co-ordinated actions in a dispersed neuronal network

(2011) Kevin W. Williams et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Obesity is associated with hypothalamic injury in rodents and humans

(2011) Joshua P. Thaler et al.   JOURNAL OF CLINICAL INVESTIGATION

Cyto- and chemoarchitecture of the hypothalamic paraventricular nucleus in the C57BL/6J male mouse: A study of immunostaining and multiple fluorescent tract tracing

(2011) Jonathan Biag et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Transcriptional and epigenetic mechanisms of addiction

(2011) Alfred J. Robison et al.   NATURE REVIEWS NEUROSCIENCE

Leptin Action on GABAergic Neurons Prevents Obesity and Reduces Inhibitory Tone to POMC Neurons

(2011) Linh Vong et al.   NEURON

Central control of thermogenesis

(2011) John C. Clapham   NEUROPHARMACOLOGY

Reduction of high-fat diet-induced obesity after chronic administration of brain-derived neurotrophic factor in the hypothalamic ventromedial nucleus

(2011) R. Godar et al.   NEUROSCIENCE

Brain-derived neurotrophic factor (BDNF) in the hypothalamic ventromedial nucleus increases energy expenditure

(2010) ChuanFeng Wang et al.   BRAIN RESEARCH

Associations of Six Single Nucleotide Polymorphisms in Obesity-Related Genes With BMI and Risk of Obesity in Chinese Children

(2010) L. Wu et al.   DIABETES

The biological control of voluntary exercise, spontaneous physical activity and daily energy expenditure in relation to obesity: human and rodent perspectives

(2010) T. Garland et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Brain-Derived Neurotrophic Factor Regulates Hedonic Feeding by Acting on the Mesolimbic Dopamine System

(2010) J. W. Cordeira et al.   JOURNAL OF NEUROSCIENCE

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

(2010) Elizabeth K Speliotes et al.   NATURE GENETICS

The Geometry of Leptin Action in the Brain: More Complicated Than a Simple ARC

(2009) Martin G. Myers et al.   Cell Metabolism

Brain-Derived Neurotrophic Factor/Tropomyosin-Related Kinase Receptor Type B Signaling Is a Downstream Effector of the Brainstem Melanocortin System in Food Intake Control

(2009) Bruno Bariohay et al.   ENDOCRINOLOGY

Association between obesity and polymorphisms in SEC16B, TMEM18, GNPDA2, BDNF, FAIM2 and MC4R in a Japanese population

(2009) Kikuko Hotta et al.   JOURNAL OF HUMAN GENETICS

The Role of Obesity-associated Loci Identified in Genome-wide Association Studies in the Determination of Pediatric BMI

(2009) Jianhua Zhao et al.   Obesity

Distinct Role of Long 3′ UTR BDNF mRNA in Spine Morphology and Synaptic Plasticity in Hippocampal Neurons

(2008) Juan Ji An et al.   CELL

Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity

(2008) Gudmar Thorleifsson et al.   NATURE GENETICS

Brain-Derived Neurotrophic Factor and Obesity in the WAGR Syndrome

(2008) Joan C. Han et al.   NEW ENGLAND JOURNAL OF MEDICINE

Appetite Enhancement and Weight Gain by Peripheral Administration of TrkB Agonists in Non-Human Primates

(2008) John C. Lin et al.   PLoS One