Transcriptional and epigenetic mechanisms of addiction

The epigenetic landscape of addiction

(2011) Ian Maze et al.   Annals of the New York Academy of Sciences

Hydroxylation of 5-Methylcytosine by TET1 Promotes Active DNA Demethylation in the Adult Brain

(2011) Junjie U. Guo et al.   CELL

I B Kinase Regulates Social Defeat Stress-Induced Synaptic and Behavioral Plasticity

(2011) D. J. Christoffel et al.   JOURNAL OF NEUROSCIENCE

TET1 and hydroxymethylcytosine in transcription and DNA methylation fidelity

(2011) Kristine Williams et al.   NATURE

Genome-wide mapping of 5-hydroxymethylcytosine in embryonic stem cells

(2011) William A. Pastor et al.   NATURE

Dynamic regulation of 5-hydroxymethylcytosine in mouse ES cells and during differentiation

(2011) Gabriella Ficz et al.   NATURE

Dual functions of Tet1 in transcriptional regulation in mouse embryonic stem cells

(2011) Hao Wu et al.   NATURE

Efficient construction of sequence-specific TAL effectors for modulating mammalian transcription

(2011) Feng Zhang et al.   NATURE BIOTECHNOLOGY

Regulation of MiR-124, Let-7d and MiR-181a in the Accumbens Affects the Expression, Extinction and Reinstatement of Cocaine-Induced Conditioned Place Preference

(2011) Vijay Chandrasekar et al.   NEUROPSYCHOPHARMACOLOGY

Cocaine dynamically regulates heterochromatin and repetitive element unsilencing in nucleus accumbens

(2011) I. Maze et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

microRNA-Seq reveals cocaine-regulated expression of striatal microRNAs

(2011) J. E. Eipper-Mains et al.   RNA

Neurobiology of the incubation of drug craving

(2011) Charles L. Pickens et al.   TRENDS IN NEUROSCIENCES

Glucocorticoid receptor (NR3C1) gene polymorphisms and onset of alcohol abuse in adolescents

(2010) Sylvane Desrivières et al.   ADDICTION BIOLOGY

Glucocorticoid Receptors in Dopaminoceptive Neurons, Key for Cocaine, Are Dispensable for Molecular and Behavioral Morphine Responses

(2010) Jacques Barik et al.   BIOLOGICAL PSYCHIATRY

Chronic ethanol feeding impairs AMPK and MEF2 expression and is associated with GLUT4 decrease in rat myocardium

(2010) LiYong Chen et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

ΔFosB in the nucleus accumbens is critical for reinforcing effects of sexual reward

(2010) K. K. Pitchers et al.   GENES BRAIN AND BEHAVIOR

Argonaute 2 in dopamine 2 receptor–expressing neurons regulates cocaine addiction

(2010) Anne Schaefer et al.   JOURNAL OF EXPERIMENTAL MEDICINE

An Engineered Zinc Finger Protein Activator of the Endogenous Glial Cell Line-Derived Neurotrophic Factor Gene Provides Functional Neuroprotection in a Rat Model of Parkinson's Disease

(2010) J. Laganiere et al.   JOURNAL OF NEUROSCIENCE

Regulation of Opioid Tolerance by let-7 Family MicroRNA Targeting the   Opioid Receptor

(2010) Y. He et al.   JOURNAL OF NEUROSCIENCE

Morphine Regulates Dopaminergic Neuron Differentiation via miR-133b

(2010) F. M. Sanchez-Simon et al.   MOLECULAR PHARMACOLOGY

Striatal microRNA controls cocaine intake through CREB signalling

(2010) Jonathan A. Hollander et al.   NATURE

MeCP2 controls BDNF expression and cocaine intake through homeostatic interactions with microRNA-212

(2010) Heh-In Im et al.   NATURE NEUROSCIENCE

ΔFosB in brain reward circuits mediates resilience to stress and antidepressant responses

(2010) Vincent Vialou et al.   NATURE NEUROSCIENCE

MeCP2 in the nucleus accumbens contributes to neural and behavioral responses to psychostimulants

(2010) Jie V Deng et al.   NATURE NEUROSCIENCE

Dnmt3a regulates emotional behavior and spine plasticity in the nucleus accumbens

(2010) Quincey LaPlant et al.   NATURE NEUROSCIENCE

AMPA receptor plasticity in the nucleus accumbens after repeated exposure to cocaine

(2010) Marina E. Wolf et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

The predictive validity of the rat self-administration model for abuse liability

(2010) Eoin C. O’Connor et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Essential role of the cAMP-cAMP response-element binding protein pathway in opiate-induced homeostatic adaptations of locus coeruleus neurons

(2010) J.-L. Cao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Developmental regulation and individual differences of neuronal H3K4me3 epigenomes in the prefrontal cortex

(2010) I. Cheung et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cell Type-Specific Loss of BDNF Signaling Mimics Optogenetic Control of Cocaine Reward

(2010) M. K. Lobo et al.   SCIENCE

Cholinergic Interneurons Control Local Circuit Activity and Cocaine Conditioning

(2010) I. B. Witten et al.   SCIENCE

Essential Role of the Histone Methyltransferase G9a in Cocaine-Induced Plasticity

(2010) I. Maze et al.   SCIENCE

The addicted synapse: mechanisms of synaptic and structural plasticity in nucleus accumbens

(2010) Scott J. Russo et al.   TRENDS IN NEUROSCIENCES

Epigenetic Regulation in Substance Use Disorders

(2010) Susan C. McQuown et al.   Current Psychiatry Reports

Molecular and genetic substrates linking stress and addiction

(2009) Lisa A. Briand et al.   BRAIN RESEARCH

The locus coeruleus: A key nucleus where stress and opioids intersect to mediate vulnerability to opiate abuse

(2009) E.J. Van Bockstaele et al.   BRAIN RESEARCH

Δ FosB overexpression in the nucleus accumbens enhances sexual reward in female Syrian hamsters

(2009) V. L. Hedges et al.   GENES BRAIN AND BEHAVIOR

Sex differences and ovarian hormones in animal models of drug dependence

(2009) Marilyn E. Carroll et al.   HORMONES AND BEHAVIOR

Nuclear Factor  B Signaling Regulates Neuronal Morphology and Cocaine Reward

(2009) S. J. Russo et al.   JOURNAL OF NEUROSCIENCE

Non-coding RNAs: regulators of disease

(2009) Ryan J Taft et al.   JOURNAL OF PATHOLOGY

Cocaine self-administration alters the expression of chromatin-remodelling proteins; modulation by histone deacetylase inhibition

(2009) Lionel Host et al.   JOURNAL OF PSYCHOPHARMACOLOGY

microRNAs miR-124, let-7d and miR-181a regulate Cocaine-induced Plasticity

(2009) Vijay Chandrasekar et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

 -Opioid Receptor Agonists Differentially Regulate the Expression of miR-190 and NeuroD

(2009) H. Zheng et al.   MOLECULAR PHARMACOLOGY

Recent progress in the biology and physiology of sirtuins

(2009) Toren Finkel et al.   NATURE

Stress and addiction: glucocorticoid receptor in dopaminoceptive neurons facilitates cocaine seeking

(2009) Frédéric Ambroggi et al.   NATURE NEUROSCIENCE

The glutamate homeostasis hypothesis of addiction

(2009) Peter W. Kalivas   NATURE REVIEWS NEUROSCIENCE

Appetitive Pavlovian conditioned stimuli increase CREB phosphorylation in the nucleus accumbens

(2009) Michael W. Shiflett et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Characterization of Small RNAs in Aplysia Reveals a Role for miR-124 in Constraining Synaptic Plasticity through CREB

(2009) Priyamvada Rajasethupathy et al.   NEURON

Genome-wide Analysis of Chromatin Regulation by Cocaine Reveals a Role for Sirtuins

(2009) William Renthal et al.   NEURON

Nucleus Accumbens CREB Activity is Necessary for Nicotine Conditioned Place Preference

(2009) Darlene H Brunzell et al.   NEUROPSYCHOPHARMACOLOGY

Smoking Induces Long-Lasting Effects through a Monoamine-Oxidase Epigenetic Regulation

(2009) Jean-Marie Launay et al.   PLoS One

MAOA methylation is associated with nicotine and alcohol dependence in women

(2008) Robert A. Philibert et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

ΔFosB-Mediated Alterations in Dopamine Signaling Are Normalized by a Palatable High-Fat Diet

(2008) Sarah L. Teegarden et al.   BIOLOGICAL PSYCHIATRY

Epigenetic mechanisms in mammals

(2008) J. K. Kim et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Histone Deacetylase Inhibitors Decrease Cocaine But Not Sucrose Self-Administration in Rats

(2008) P. Romieu et al.   JOURNAL OF NEUROSCIENCE

 FosB Mediates Epigenetic Desensitization of the c-fos Gene After Chronic Amphetamine Exposure

(2008) W. Renthal et al.   JOURNAL OF NEUROSCIENCE

Induction of Activating Transcription Factors (ATFs) ATF2, ATF3, and ATF4 in the Nucleus Accumbens and Their Regulation of Emotional Behavior

(2008) T. A. Green et al.   JOURNAL OF NEUROSCIENCE

The Influence of  FosB in the Nucleus Accumbens on Natural Reward-Related Behavior

(2008) D. L Wallace et al.   JOURNAL OF NEUROSCIENCE

Brain Chromatin Remodeling: A Novel Mechanism of Alcoholism

(2008) S. C. Pandey et al.   JOURNAL OF NEUROSCIENCE

Opposing Patterns of Signaling Activation in Dopamine D1 and D2 Receptor-Expressing Striatal Neurons in Response to Cocaine and Haloperidol

(2008) J. Bertran-Gonzalez et al.   JOURNAL OF NEUROSCIENCE

One SNP linked to two diseases—addiction and cancer: A Double Whammy?: Nicotine addiction and lung cancer susceptibility

(2008) N Volkow et al.   MOLECULAR PSYCHIATRY

Posttranscriptional Regulation of BK Channel Splice Variant Stability by miR-9 Underlies Neuroadaptation to Alcohol

(2008) Andrzej Z. Pietrzykowski et al.   NEURON

Decoding the Epigenetic Language of Neuronal Plasticity

(2008) Emiliana Borrelli et al.   NEURON

Cocaine Regulates MEF2 to Control Synaptic and Behavioral Plasticity

(2008) Suprabha Pulipparacharuvil et al.   NEURON

Neurotrophic factors and structural plasticity in addiction

(2008) Scott J. Russo et al.   NEUROPHARMACOLOGY

Drug-Induced Activation of Dopamine D1 Receptor Signaling and Inhibition of Class I/II Histone Deacetylase Induce Chromatin Remodeling in Reward Circuitry and Modulate Cocaine-Related Behaviors

(2008) Frederick A Schroeder et al.   NEUROPSYCHOPHARMACOLOGY

Phosphorylation of ΔFosB mediates its stability in vivo

(2008) P.G. Ulery-Reynolds et al.   NEUROSCIENCE

Desperately driven and no brakes: Developmental stress exposure and subsequent risk for substance abuse

(2008) Susan L. Andersen et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Chronic microinjection of valproic acid into the nucleus accumbens attenuates amphetamine-induced locomotor activity

(2008) Wha Young Kim et al.   NEUROSCIENCE LETTERS

ΔFosB induction in orbitofrontal cortex potentiates locomotor sensitization despite attenuating the cognitive dysfunction caused by cocaine

(2008) Catharine A. Winstanley et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Transcriptional mechanisms of addiction: role of  FosB

(2008) E. J Nestler   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Distinct patterns of ΔFosB induction in brain by drugs of abuse

(2008) L.I. Perrotti et al.   SYNAPSE

Epigenetic mechanisms in drug addiction

(2008) William Renthal et al.   TRENDS IN MOLECULAR MEDICINE