Glutamatergic neuron-targeted loss of LGI1 epilepsy gene results in seizures

Direct excitation of parvalbumin-positive interneurons by M1muscarinic acetylcholine receptors: roles in cellular excitability, inhibitory transmission and cognition

(2014) Feng Yi et al.   JOURNAL OF PHYSIOLOGY-LONDON

Faciobrachial dystonic seizures: the influence of immunotherapy on seizure control and prevention of cognitive impairment in a broadening phenotype

(2013) Sarosh R. Irani et al.   BRAIN

Seizure semiology in autosomal dominant epilepsy with auditory features, due to novel LGI1 mutations

(2013) Lynette G. Sadleir et al.   EPILEPSY RESEARCH

Autoantibodies to Epilepsy-Related LGI1 in Limbic Encephalitis Neutralize LGI1-ADAM22 Interaction and Reduce Synaptic AMPA Receptors

(2013) T. Ohkawa et al.   JOURNAL OF NEUROSCIENCE

A newly discovered LGI1 mutation in Korean family with autosomal dominant lateral temporal lobe epilepsy

(2013) Moon Kyu Lee et al.   SEIZURE-EUROPEAN JOURNAL OF EPILEPSY

Decreased susceptibility to seizures induced by pentylenetetrazole in serine racemase knockout mice

(2012) Tomomi Harai et al.   EPILEPSY RESEARCH

A rat model for LGI1-related epilepsies

(2012) Stéphanie Baulac et al.   HUMAN MOLECULAR GENETICS

Epilepsy Gene LGI1 Regulates Postnatal Developmental Remodeling of Retinogeniculate Synapses

(2012) Y.-D. Zhou et al.   JOURNAL OF NEUROSCIENCE

LGI1microdeletion in autosomal dominant lateral temporal epilepsy

(2012) M. Fanciulli et al.   NEUROLOGY

Identification of Arx targets unveils new candidates for controlling cortical interneuron migration and differentiation

(2012) Gaëlle Friocourt   Frontiers in Cellular Neuroscience

A Nestin-cre transgenic mouse is insufficient for recombination in early embryonic neural progenitors

(2012) H. Liang et al.   Biology Open

The temporal and spatial expression pattern of the LGI1 epilepsy predisposition gene during mouse embryonic cranial development

(2011) Jeane Silva et al.   BMC NEUROSCIENCE

Low penetrance and effect on protein secretion of LGI1 mutations causing autosomal dominant lateral temporal epilepsy

(2011) Carlo Di Bonaventura et al.   EPILEPSIA

Mutant LGI1 inhibits seizure-induced trafficking of Kv4.2 potassium channels

(2011) Stephen E. P. Smith et al.   JOURNAL OF NEUROCHEMISTRY

Familial temporal lobe epilepsy with psychic auras associated with a novel LGI1 mutation

(2011) P. Striano et al.   NEUROLOGY

A Computational Model of the LGI1 Protein Suggests a Common Binding Site for ADAM Proteins

(2011) Emanuela Leonardi et al.   PLoS One

Electroclinical characterization of epileptic seizures in leucine-rich, glioma-inactivated 1-deficient mice

(2010) Elodie Chabrol et al.   BRAIN

Antibodies to Kv1 potassium channel-complex proteins leucine-rich, glioma inactivated 1 protein and contactin-associated protein-2 in limbic encephalitis, Morvan’s syndrome and acquired neuromyotonia

(2010) Sarosh R. Irani et al.   BRAIN

Knockdown of zebrafish Lgi1a results in abnormal development, brain defects and a seizure-like behavioral phenotype

(2010) Y. Teng et al.   HUMAN MOLECULAR GENETICS

Lgi1 null mutant mice exhibit myoclonic seizures and CA1 neuronal hyperexcitability

(2010) Y. Eugene Yu et al.   HUMAN MOLECULAR GENETICS

LGI1 Is a Nogo Receptor 1 Ligand that Antagonizes Myelin-Based Growth Inhibition

(2010) R. Thomas et al.   JOURNAL OF NEUROSCIENCE

Investigation of LGI1 as the antigen in limbic encephalitis previously attributed to potassium channels: a case series

(2010) Meizan Lai et al.   LANCET NEUROLOGY

Disruption of LGI1–linked synaptic complex causes abnormal synaptic transmission and epilepsy

(2010) Yuko Fukata et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lateral temporal lobe epilepsies: Clinical and genetic features

(2009) Roberto Michelucci et al.   EPILEPSIA

A novel three base-pair LGI1 deletion leading to loss of function in a family with autosomal dominant lateral temporal epilepsy and migraine-like episodes

(2009) Julitta de Bellescize et al.   EPILEPSY RESEARCH

LGI1mutations in autosomal dominant and sporadic lateral temporal epilepsy

(2009) Carlo Nobile et al.   HUMAN MUTATION

Arrested maturation of excitatory synapses in autosomal dominant lateral temporal lobe epilepsy

(2009) Yu-Dong Zhou et al.   NATURE MEDICINE

A robust and high-throughput Cre reporting and characterization system for the whole mouse brain

(2009) Linda Madisen et al.   NATURE NEUROSCIENCE

Reelin Secreted by GABAergic Neurons Regulates Glutamate Receptor Homeostasis

(2009) Cecilia Gonzalez Campo et al.   PLoS One

A Novel Loss-of-Function LGI1 Mutation Linked to Autosomal Dominant Lateral Temporal Epilepsy

(2008) Pasquale Striano et al.   ARCHIVES OF NEUROLOGY

Mechanisms of human inherited epilepsies

(2008) Christopher A. Reid et al.   PROGRESS IN NEUROBIOLOGY