Sulforaphane, an NRF2 agonist, alleviates ferroptosis in acute liver failure by regulating HDAC6 activity

The heart as a target for deltamethrin toxicity: Inhibition of Nrf2/HO-1 pathway induces oxidative stress and results in inflammation and apoptosis

(2022) Xue Yang et al.   CHEMOSPHERE

NOD2 ‐mediated HDAC6 / NF ‐κb signalling pathway regulates ferroptosis induced by extracellular histone H3 in acute liver failure

(2022) Qian Chen et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Nrf2 and its dependent autophagy activation cooperatively counteract ferroptosis to alleviate acute liver injury

(2022) Jiawei Liu et al.   PHARMACOLOGICAL RESEARCH

HDAC 6 inhibitor ACY 1215 inhibits the activation of NLRP 3 inflammasome in acute liver failure by regulating the ATM/F ‐actin signalling pathway

(2021) Qian Chen et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Ferroptosis is essential for diabetic cardiomyopathy and is prevented by sulforaphane via AMPK/NRF2 pathways

(2021) Xiang Wang et al.   Acta Pharmaceutica Sinica B

NRF2 as a regulator of cell metabolism and inflammation in cancer

(2020) Feng He et al.   CARCINOGENESIS

Gut-Resident Lactobacilli Activate Hepatic Nrf2 and Protect Against Oxidative Liver Injury

(2020) Bejan J. Saeedi et al.   Cell Metabolism

Emerging Mechanisms and Disease Relevance of Ferroptosis

(2020) Brent R. Stockwell et al.   TRENDS IN CELL BIOLOGY

Ferroptosis mediated by the interaction between Mfn2 and IREα promotes arsenic-induced nonalcoholic steatohepatitis

(2020) Sen Wei et al.   ENVIRONMENTAL RESEARCH

Efficacy of Sulforaphane in Neurodegenerative Diseases

(2020) Giovanni Schepici et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Epigenetic regulators of neuronal ferroptosis identify novel therapeutics for neurological diseases: HDACs, transglutaminases, and HIF prolyl hydroxylases

(2020) Orjon Rroji et al.   NEUROBIOLOGY OF DISEASE

Sulforaphane Attenuates Isoproterenol-Induced Myocardial Injury in Mice

(2020) Lijuan Song et al.   Biomed Research International

Sulforaphane ameliorates ethanol plus carbon tetrachloride-induced liver fibrosis in mice through the Nrf2-mediated antioxidant response and acetaldehyde metabolization with inhibition of the LPS/TLR4 signaling pathway

(2020) Koji Ishida et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

NRF2 plays a critical role in mitigating lipid peroxidation and ferroptosis

(2019) Matthew Dodson et al.   Redox Biology

Sulforaphane-Enriched Broccoli Sprouts Pretreated by Pulsed Electric Fields Reduces Neuroinflammation and Ameliorates Scopolamine-Induced Amnesia in Mouse Brain through Its Antioxidant Ability via Nrf2-HO-1 Activation

(2019) Lalita Subedi et al.   Oxidative Medicine and Cellular Longevity

Sulfoaphane - role in aging and neurodegeneration

(2019) Roberto Santín-Márquez et al.   GeroScience

HO-1 reduces heat stress-induced apoptosis in bovine granulosa cells by suppressing oxidative stress

(2019) Yiru Wang et al.   Aging-US

Critical role of IL-1β in the pathogenesis of Agrocybe aegerita galectin-induced liver injury through recruiting T cell to liver

(2019) Wenhui Yu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

GPx4, Lipid Peroxidation, and Cell Death: Discoveries, Rediscoveries, and Open Issues

(2018) Matilde Maiorino et al.   ANTIOXIDANTS & REDOX SIGNALING

Relevance of the natural HDAC inhibitor sulforaphane as a chemopreventive agent in urologic tumors

(2018) Eva Juengel et al.   CANCER LETTERS

Anti-cancer effects of naturally derived compounds targeting histone deacetylase 6-related pathways

(2018) Manon Lernoux et al.   PHARMACOLOGICAL RESEARCH

Exosomes derived from human menstrual blood-derived stem cells alleviate fulminant hepatic failure

(2017) Lu Chen et al.   Stem Cell Research & Therapy

Anticancer Effects of a New SIRT Inhibitor, MHY2256, against Human Breast Cancer MCF-7 Cells via Regulation of MDM2-p53 Binding

(2016) Eun Young Park et al.   International Journal of Biological Sciences

ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition

(2016) Sebastian Doll et al.   Nature Chemical Biology

Essential role of insulin-like growth factor 2 in resistance to histone deacetylase inhibitors

(2016) S-C Lee et al.   ONCOGENE

Sulforaphane attenuates hepatic fibrosis via NF-E2-related factor 2-mediated inhibition of transforming growth factor-β/Smad signaling

(2011) Chang Joo Oh et al.   FREE RADICAL BIOLOGY AND MEDICINE