How sisters grow apart: mycobacterial growth and division

Comparative genomics for mycobacterial peptidoglycan remodelling enzymes reveals extensive genetic multiplicity

(2014) Edith Machowski et al.   BMC MICROBIOLOGY

Nonclassical Transpeptidases of Mycobacterium tuberculosis Alter Cell Size, Morphology, the Cytosolic Matrix, Protein Localization, Virulence, and Resistance to  -Lactams

(2014) M. K. Schoonmaker et al.   JOURNAL OF BACTERIOLOGY

Mycobacterium tuberculosis Proteins Involved in Mycolic Acid Synthesis and Transport Localize Dynamically to the Old Growing Pole and Septum

(2014) Clément Carel et al.   PLoS One

Mycobacterial outer membrane is a lipid bilayer and the inner membrane is unusually rich in diacyl phosphatidylinositol dimannosides

(2014) Ritu Bansal-Mutalik et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mycobacterium tuberculosis FtsX extracellular domain activates the peptidoglycan hydrolase, RipC

(2014) D. Mavrici et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mycobacterium tuberculosis CwsA overproduction modulates cell division and cell wall synthesis

(2014) P. Plocinski et al.   TUBERCULOSIS

Biological Consequences and Advantages of Asymmetric Bacterial Growth

(2013) David T. Kysela et al.   Annual Review of Microbiology

Tryptophan Biosynthesis Protects Mycobacteria from CD4 T-Cell-Mediated Killing

(2013) Yanjia J. Zhang et al.   CELL

Direct interaction of FtsZ and MreB is required for septum synthesis and cell division in Escherichia coli

(2013) Andrew K Fenton et al.   EMBO JOURNAL

IntracellularMycobacterium tuberculosisExploits Host-derived Fatty Acids to Limit Metabolic Stress

(2013) Wonsik Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MmpL11 Protein Transports Mycolic Acid-containing Lipids to the Mycobacterial Cell Wall and Contributes to Biofilm Formation in Mycobacterium smegmatis

(2013) Sophia A. Pacheco et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Microenvironments in Tuberculous Granulomas Are Delineated by Distinct Populations of Macrophage Subsets and Expression of Nitric Oxide Synthase and Arginase Isoforms

(2013) J. T. Mattila et al.   JOURNAL OF IMMUNOLOGY

N-Glycolylated Peptidoglycan Contributes to the Immunogenicity but Not Pathogenicity of Mycobacterium tuberculosis

(2013) Jesse M. Hansen et al.   JOURNAL OF INFECTIOUS DISEASES

Colocalization and interaction between elongasome and divisome during a preparative cell division phase inEscherichia coli

(2013) René van der Ploeg et al.   MOLECULAR MICROBIOLOGY

FtsEX is required for CwlO peptidoglycan hydrolase activity during cell wall elongation inBacillus subtilis

(2013) Jeffrey Meisner et al.   MOLECULAR MICROBIOLOGY

Transcriptional regulation of fatty acid biosynthesis in mycobacteria

(2013) S. Mondino et al.   MOLECULAR MICROBIOLOGY

Asymmetric growth and division inMycobacteriumspp.: compensatory mechanisms for non-medial septa

(2013) Bhupender Singh et al.   MOLECULAR MICROBIOLOGY

The Mycobacterium tuberculosis regulatory network and hypoxia

(2013) James E. Galagan et al.   NATURE

Mycobacteria manipulate macrophage recruitment through coordinated use of membrane lipids

(2013) C. J. Cambier et al.   NATURE

Genomic analysis identifies targets of convergent positive selection in drug-resistant Mycobacterium tuberculosis

(2013) Maha R Farhat et al.   NATURE GENETICS

Sterilization of granulomas is common in active and latent tuberculosis despite within-host variability in bacterial killing

(2013) Philana Ling Lin et al.   NATURE MEDICINE

Advances in the development of new tuberculosis drugs and treatment regimens

(2013) Alimuddin Zumla et al.   NATURE REVIEWS DRUG DISCOVERY

Multifunctional essentiality of succinate metabolism in adaptation to hypoxia in Mycobacterium tuberculosis

(2013) H. Eoh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

FtsZ Protofilaments Use a Hinge-Opening Mechanism for Constrictive Force Generation

(2013) Y. Li et al.   SCIENCE

Dynamic Persistence of Antibiotic-Stressed Mycobacteria

(2013) Y. Wakamoto et al.   SCIENCE

Protein Complexes and Proteolytic Activation of the Cell Wall Hydrolase RipA Regulate Septal Resolution in Mycobacteria

(2013) Michael C. Chao et al.   PLoS Pathogens

Cholesterol Catabolism by Mycobacterium tuberculosis Requires Transcriptional and Metabolic Adaptations

(2012) Jennifer E. Griffin et al.   CHEMISTRY & BIOLOGY

MmpL Genes Are Associated with Mycolic Acid Metabolism in Mycobacteria and Corynebacteria

(2012) Cristian Varela et al.   CHEMISTRY & BIOLOGY

Mycobacterium tuberculosis Lacking All Mycolic Acid Cyclopropanation Is Viable but Highly Attenuated and Hyperinflammatory in Mice

(2012) Daniel Barkan et al.   INFECTION AND IMMUNITY

Mycobacterium tuberculosis CwsA Interacts with CrgA and Wag31, and the CrgA-CwsA Complex Is Involved in Peptidoglycan Synthesis and Cell Shape Determination

(2012) P. Plocinski et al.   JOURNAL OF BACTERIOLOGY

Septal Localization of theMycobacterium tuberculosisMtrB Sensor Kinase Promotes MtrA Regulon Expression

(2012) Renata Plocinska et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphorylation of Mycobacterial PcaA Inhibits Mycolic Acid Cyclopropanation

(2012) Rosa Milagros Corrales et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Meropenem inhibits D,D-carboxypeptidase activity inMycobacterium tuberculosis

(2012) Pradeep Kumar et al.   MOLECULAR MICROBIOLOGY

Three redundant murein endopeptidases catalyse an essential cleavage step in peptidoglycan synthesis ofEscherichia coliK12

(2012) Santosh Kumar Singh et al.   MOLECULAR MICROBIOLOGY

Inhibition of mycolic acid transport across the Mycobacterium tuberculosis plasma membrane

(2012) Anna E Grzegorzewicz et al.   Nature Chemical Biology

Cell Division Site Placement and Asymmetric Growth in Mycobacteria

(2012) Graham Joyce et al.   PLoS One

Global Assessment of Genomic Regions Required for Growth in Mycobacterium tuberculosis

(2012) Yanjia J. Zhang et al.   PLoS Pathogens

A bioanalytical method to determine the cell wall composition of Mycobacterium tuberculosis grown in vivo

(2011) Suresh Bhamidi et al.   ANALYTICAL BIOCHEMISTRY

Tuberculosis Pathogenesis and Immunity

(2011) Jennifer A. Philips et al.   Annual Review of Pathology-Mechanisms of Disease

Regulation of Polar Peptidoglycan Biosynthesis by Wag31 Phosphorylation in Mycobacteria

(2011) Charul Jani et al.   BMC MICROBIOLOGY

Mycobacterium tuberculosis septum site determining protein, Ssd encoded by rv3660c, promotes filamentation and elicits an alternative metabolic and dormancy stress response

(2011) Kathleen England et al.   BMC MICROBIOLOGY

A Comparative Lipidomics Platform for Chemotaxonomic Analysis of Mycobacterium tuberculosis

(2011) Emilie Layre et al.   CHEMISTRY & BIOLOGY

Characterization of CrgA, a New Partner of the Mycobacterium tuberculosis Peptidoglycan Polymerization Complexes

(2011) P. Plocinski et al.   JOURNAL OF BACTERIOLOGY

Use of whole genome sequencing to estimate the mutation rate of Mycobacterium tuberculosis during latent infection

(2011) Christopher B Ford et al.   NATURE GENETICS

Asymmetry and Aging of Mycobacterial Cells Lead to Variable Growth and Antibiotic Susceptibility

(2011) B. B. Aldridge et al.   SCIENCE

Coupled, Circumferential Motions of the Cell Wall Synthesis Machinery and MreB Filaments in B. subtilis

(2011) E. C. Garner et al.   SCIENCE

Metabolic Regulation of Mycobacterial Growth and Antibiotic Sensitivity

(2011) Seung-Hun Baek et al.   PLOS BIOLOGY

High-Resolution Phenotypic Profiling Defines Genes Essential for Mycobacterial Growth and Cholesterol Catabolism

(2011) Jennifer E. Griffin et al.   PLoS Pathogens

Letting Sleeping dos Lie: Does Dormancy Play a Role in Tuberculosis?

(2010) Michael C. Chao et al.   Annual Review of Microbiology

Cell polarity and the control of apical growth in Streptomyces

(2010) Klas Flärdh   CURRENT OPINION IN MICROBIOLOGY

Advances in understanding E. coli cell fission

(2010) Piet AJ de Boer   CURRENT OPINION IN MICROBIOLOGY

Molecular structure of the Mycobacterium tuberculosis virulence factor, mycolic acid, determines the elicited inflammatory pattern

(2010) Seppe Vander Beken et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

A Role for the Class A Penicillin-Binding Protein PonA2 in the Survival of Mycobacterium smegmatis under Conditions of Nonreplication

(2010) M.-M. Patru et al.   JOURNAL OF BACTERIOLOGY

Biosynthetic Origin of the Galactosamine Substituent of Arabinogalactan inMycobacterium tuberculosis

(2010) Henrieta Škovierová et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mycobacterium tuberculosisOrigin of Replication and the Promoter for Immunodominant Secreted Antigen 85B Are the Targets of MtrA, the Essential Response Regulator

(2010) Malini Rajagopalan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphorylation of theMycobacterium tuberculosisβ-Ketoacyl-Acyl Carrier Protein Reductase MabA Regulates Mycolic Acid Biosynthesis

(2010) Romain Veyron-Churlet et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genetic Requirements for the Survival of Tubercle Bacilli in Primates

(2010) Noton K. Dutta et al.   JOURNAL OF INFECTIOUS DISEASES

“Depupylation” of Prokaryotic Ubiquitin-like Protein from Mycobacterial Proteasome Substrates

(2010) Kristin E. Burns et al.   MOLECULAR CELL

Phosphorylation of InhA inhibits mycolic acid biosynthesis and growth of Mycobacterium tuberculosis

(2010) Virginie Molle et al.   MOLECULAR MICROBIOLOGY

Division and cell envelope regulation by Ser/Thr phosphorylation:Mycobacteriumshows the way

(2010) Virginie Molle et al.   MOLECULAR MICROBIOLOGY

The Mycobacterium tuberculosis protein LdtMt2 is a nonclassical transpeptidase required for virulence and resistance to amoxicillin

(2010) Radhika Gupta et al.   NATURE MEDICINE

Prokayrotic Ubiquitin-Like Protein (Pup) Proteome of Mycobacterium tuberculosis

(2010) Richard A. Festa et al.   PLoS One

Novel Role of Phosphorylation-Dependent Interaction between FtsZ and FipA in Mycobacterial Cell Division

(2010) Kamakshi Sureka et al.   PLoS One

Mycobacterium tuberculosis ClpX Interacts with FtsZ and Interferes with FtsZ Assembly

(2010) Renata Dziedzic et al.   PLoS One

Extensive phosphorylation with overlapping specificity by Mycobacterium tuberculosis serine/threonine protein kinases

(2010) S. Prisic et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure and Functional Regulation of RipA, a Mycobacterial Enzyme Essential for Daughter Cell Separation

(2010) Alessia Ruggiero et al.   STRUCTURE

Direct Visualization by Cryo-EM of the Mycobacterial Capsular Layer: A Labile Structure Containing ESX-1-Secreted Proteins

(2010) Musa Sani et al.   PLoS Pathogens

Interaction and Modulation of Two Antagonistic Cell Wall Enzymes of Mycobacteria

(2010) Erik C. Hett et al.   PLoS Pathogens

The Role of the Granuloma in Expansion and Dissemination of Early Tuberculous Infection

(2009) J. Muse Davis et al.   CELL

The Dual Function of the Mycobacterium tuberculosis FadD32 Required for Mycolic Acid Biosynthesis

(2009) Mathieu Léger et al.   CHEMISTRY & BIOLOGY

AftD, a novel essential arabinofuranosyltransferase from mycobacteria

(2009) Henrieta Škovierová et al.   GLYCOBIOLOGY

Increased NOD2-mediated recognition ofN-glycolyl muramyl dipeptide

(2009) François Coulombe et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Novel role of Wag31 in protection of mycobacteria under oxidative stress

(2009) Partha Mukherjee et al.   MOLECULAR MICROBIOLOGY

Regulation of cell wall morphogenesis inBacillus subtilisby recruitment of PBP1 to the MreB helix

(2009) Yoshikazu Kawai et al.   MOLECULAR MICROBIOLOGY

A replication clock for Mycobacterium tuberculosis

(2009) Wendy P Gill et al.   NATURE MEDICINE

Bacterial cell division: assembly, maintenance and disassembly of the Z ring

(2009) David W. Adams et al.   NATURE REVIEWS MICROBIOLOGY

The Genetic Requirements for Fast and Slow Growth in Mycobacteria

(2009) Dany J. V. Beste et al.   PLoS One

Benzothiazinones Kill Mycobacterium tuberculosis by Blocking Arabinan Synthesis

(2009) V. Makarov et al.   SCIENCE

Tuberculous Granulomas Are Hypoxic in Guinea Pigs, Rabbits, and Nonhuman Primates

(2008) L. E. Via et al.   INFECTION AND IMMUNITY

Morphological features and signature gene response elicited by inactivation of FtsI in Mycobacterium tuberculosis

(2008) Richard A. Slayden et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

The Peptidoglycan of Stationary-Phase Mycobacterium tuberculosis Predominantly Contains Cross-Links Generated by L,D-Transpeptidation

(2008) M. Lavollay et al.   JOURNAL OF BACTERIOLOGY

Acid-Susceptible Mutants of Mycobacterium tuberculosis Share Hypersusceptibility to Cell Wall and Oxidative Stress and to the Host Environment

(2008) O. H. Vandal et al.   JOURNAL OF BACTERIOLOGY

Bacterial Growth and Cell Division: a Mycobacterial Perspective

(2008) E. C. Hett et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Wag31, a homologue of the cell division protein DivIVA, regulates growth, morphology and polar cell wall synthesis in mycobacteria

(2008) C.-M. Kang et al.   MICROBIOLOGY-SGM

Growth ofMycobacterium tuberculosisbiofilms containing free mycolic acids and harbouring drug-tolerant bacteria

(2008) Anil K. Ojha et al.   MOLECULAR MICROBIOLOGY

Mycobacterial persistence requires the utilization of host cholesterol

(2008) A. K. Pandey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ubiquitin-Like Protein Involved in the Proteasome Pathway of Mycobacterium tuberculosis

(2008) M. J. Pearce et al.   SCIENCE

Identification of genes of Mycobacterium tuberculosis upregulated during anaerobic persistence by fluorescence and kanamycin resistance selection

(2008) Alka Saxena et al.   TUBERCULOSIS

A Mycobacterial Enzyme Essential for Cell Division Synergizes with Resuscitation-Promoting Factor

(2008) Erik C. Hett et al.   PLoS Pathogens