Acute-on-chronic liver failure: terminology, mechanisms and management

Hepatitis E virus in patients with decompensated chronic liver disease: a prospective UK/French study

(2015) H. Blasco-Perrin et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Early Liver Transplantation for Patients With Acute Alcoholic Hepatitis: Public Views and the Effects on Organ Donation

(2015) G. Stroh et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Hybrid Periportal Hepatocytes Regenerate the Injured Liver without Giving Rise to Cancer

(2015) Joan Font-Burgada et al.   CELL

Fulminant presentation of autoimmune hepatitis

(2015) Manuel Mendizabal et al.   EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY

Patients With Acute-on-Chronic Liver Failure Have Increased Numbers of Regulatory Immune Cells Expressing the Receptor Tyrosine Kinase MERTK

(2015) Christine Bernsmeier et al.   GASTROENTEROLOGY

Combination of Granulocyte Colony-Stimulating Factor and Erythropoietin Improves Outcomes of Patients With Decompensated Cirrhosis

(2015) Chandan Kumar Kedarisetty et al.   GASTROENTEROLOGY

Progenitor cell expansion and impaired hepatocyte regeneration in explanted livers from alcoholic hepatitis

(2015) Laurent Dubuquoy et al.   GUT

Clinical Course of acute-on-chronic liver failure syndrome and effects on prognosis

(2015) Thierry Gustot et al.   HEPATOLOGY

Acute-on-chronic liver failure precipitated by hepatic injury is distinct from that precipitated by extrahepatic insults

(2015) Yu Shi et al.   HEPATOLOGY

Liver transplantation in acute on chronic liver failure: challenges and an algorithm for patient selection and management

(2015) Viniyendra Pamecha et al.   Hepatology International

Gut dysbiosis in acute-on-chronic liver failure and its predictive value for mortality

(2015) Yanfei Chen et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Simple organ failure countversus CANONIC grading system for predicting mortality in acute-on-chronic liver failure

(2015) Swastik Agrawal et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Acute-on-chronic liver failure: A new syndrome that will re-classify cirrhosis

(2015) Vicente Arroyo et al.   JOURNAL OF HEPATOLOGY

Submassive hepatic necrosis distinguishes HBV-associated acute on chronic liver failure from cirrhotic patients with acute decompensation

(2015) Hai Li et al.   JOURNAL OF HEPATOLOGY

Estimates on HCV disease burden worldwide - filling the gaps

(2015) H. Wedemeyer et al.   JOURNAL OF VIRAL HEPATITIS

Acute-on-chronic liver failure

(2015) William Bernal et al.   LANCET

Hepatic progenitor cells of biliary origin with liver repopulation capacity

(2015) Wei-Yu Lu et al.   NATURE CELL BIOLOGY

Alcoholic liver disease: mechanisms of injury and targeted treatment

(2015) Alexandre Louvet et al.   Nature Reviews Gastroenterology & Hepatology

Prednisolone or Pentoxifylline for Alcoholic Hepatitis

(2015) Mark R. Thursz et al.   NEW ENGLAND JOURNAL OF MEDICINE

Predictors of mortality among patients with compensated and decompensated liver cirrhosis: the role of bacterial infections and infection-related acute-on-chronic liver failure

(2015) Konstantina Sargenti et al.   SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY

Comparison of Current Diagnostic Criteria for Acute-On-Chronic Liver Failure

(2015) Qian Zhang et al.   PLoS One

Probiotics (Lactobacillus rhamnosus R0011 and acidophilus R0052) Reduce the Expression of Toll-Like Receptor 4 in Mice with Alcoholic Liver Disease

(2015) Meegun Hong et al.   PLoS One

ACG Clinical Guideline: The Diagnosis and Management of Idiosyncratic Drug-Induced Liver Injury

(2014) Naga P Chalasani et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Granulocyte Colony-Stimulating Factor in Severe Alcoholic Hepatitis: A Randomized Pilot Study

(2014) Virendra Singh et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

The global burden of liver disease: a challenge for methods and for public health

(2014) Peter Byass   BMC Medicine

Toward an Improved Definition of Acute-on-Chronic Liver Failure

(2014) Rajiv Jalan et al.   GASTROENTEROLOGY

A Histologic Scoring System for Prognosis of Patients With Alcoholic Hepatitis

(2014) José Altamirano et al.   GASTROENTEROLOGY

Liver injury in acute hepatitis A is associated with decreased frequency of regulatory T cells caused by Fas-mediated apoptosis

(2014) Yoon Seok Choi et al.   GUT

Survival in infection-related acute-on-chronic liver failure is defined by extrahepatic organ failures

(2014) Jasmohan S. Bajaj et al.   HEPATOLOGY

Liver dialysis in acute-on-chronic liver failure: current and future perspectives

(2014) Rakhi Maiwall et al.   Hepatology International

Acute-on-chronic liver failure: consensus recommendations of the Asian Pacific Association for the Study of the Liver (APASL) 2014

(2014) Shiv Kumar Sarin et al.   Hepatology International

Hepatic stellate cells contribute to progenitor cells and liver regeneration

(2014) Claus Kordes et al.   JOURNAL OF CLINICAL INVESTIGATION

Cirrhosis-associated immune dysfunction: Distinctive features and clinical relevance

(2014) Agustín Albillos et al.   JOURNAL OF HEPATOLOGY

Prognosis of acute severe autoimmune hepatitis (AS-AIH): The role of corticosteroids in modifying outcome

(2014) Andrew D. Yeoman et al.   JOURNAL OF HEPATOLOGY

Pentoxifylline vs. corticosteroid to treat severe alcoholic hepatitis: A randomised, non-inferiority, open trial

(2014) Seung Ha Park et al.   JOURNAL OF HEPATOLOGY

P329 BASELINE LIVER BIOPSY CAN PREDICT RESPONSE TO STEROIDS IN PATIENTS WITH SEVERE ALCOHOLIC HEPATITIS

(2014) S.M. Shasthry et al.   JOURNAL OF HEPATOLOGY

Single-centre validation of the EASL-CLIF Consortium definition of acute-on-chronic liver failure and CLIF-SOFA for prediction of mortality in cirrhosis

(2014) Pedro E. Soares e Silva et al.   LIVER INTERNATIONAL

Stress, Inflammation, and Defense of Homeostasis

(2014) Raj Chovatiya et al.   MOLECULAR CELL

Immunosuppression in acutely decompensated cirrhosis is mediated by prostaglandin E2

(2014) Alastair J O'Brien et al.   NATURE MEDICINE

TWEAK/Fn14 Signaling Is Required for Liver Regeneration after Partial Hepatectomy in Mice

(2014) Gamze Karaca et al.   PLoS One

Risk factors and outcome of bacterial infections in cirrhosis

(2014) Tony Bruns   WORLD JOURNAL OF GASTROENTEROLOGY

Chronic Liver Failure-Sequential Organ Failure Assessment is better than the Asia-Pacific Association for the Study of Liver criteria for defining acute-on-chronic liver failure and predicting outcome

(2014) Radha K Dhiman   WORLD JOURNAL OF GASTROENTEROLOGY

Change in model for end-stage liver disease score at two weeks, as an indicator of mortality or liver transplantation at 60 days in acute-on-chronic liver failure

(2014) R. Kumar et al.   Gastroenterology Report

Effect of a carbohydrate-containing late-evening snack on energy metabolism and fasting substrate utilization in adults with acute-on-chronic liver failure due to Hepatitis B

(2013) W Hou et al.   EUROPEAN JOURNAL OF CLINICAL NUTRITION

Defining Acute-on-Chronic Liver Failure: Will East and West Ever Meet?

(2013) Jasmohan S. Bajaj   GASTROENTEROLOGY

Liver Regeneration During Acute-on-Chronic Liver Failure Using Growth Factors: In Vivo or Ex Vivo Indulgence of Bone Marrow?

(2013) Rakhi Maiwal et al.   GASTROENTEROLOGY

Acute-on-Chronic Liver Failure Is a Distinct Syndrome That Develops in Patients With Acute Decompensation of Cirrhosis

(2013) Richard Moreau et al.   GASTROENTEROLOGY

Steroid use in acute liver failure

(2013) Jamuna Karkhanis et al.   HEPATOLOGY

M2 Kupffer cells promote M1 Kupffer cell apoptosis: A protective mechanism against alcoholic and nonalcoholic fatty liver disease

(2013) Jinghong Wan et al.   HEPATOLOGY

Poster Sessions

(2013)   HEPATOLOGY

Increased MerTK expression in circulating innate immune cells of patients with septic shock

(2013) Caroline Guignant et al.   INTENSIVE CARE MEDICINE

Hepatic and systemic hemodynamic derangements predict early mortality and recovery in patients with acute-on-chronic liver failure

(2013) Hitendra Garg et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Lessons from look-back in acute liver failure? A single centre experience of 3300 patients

(2013) William Bernal et al.   JOURNAL OF HEPATOLOGY

Liver transplantation in acute-on-chronic liver failure patients with high model for end-stage liver disease (MELD) scores: a single center experience of 100 consecutive cases

(2013) Bin-Wei Duan et al.   JOURNAL OF SURGICAL RESEARCH

Ammonia clearance with haemofiltration in adults with liver disease

(2013) Andrew J. Slack et al.   LIVER INTERNATIONAL

Altered Frequencies of Dendritic Cells and IFN-γ-secreting T Cells with Granulocyte Colony-Stimulating Factor (G-CSF) Therapy in Acute-on-Chronic Liver Failure

(2013) Arshi Khanam et al.   LIVER INTERNATIONAL

Acute-on-chronic liver failure: Excellent outcomes after liver transplantation but high mortality on the wait list

(2013) Armin Finkenstedt et al.   LIVER TRANSPLANTATION

The global NAFLD epidemic

(2013) Rohit Loomba et al.   Nature Reviews Gastroenterology & Hepatology

Management of patients with hepatitis B who require immunosuppressive therapy

(2013) Jessica P. Hwang et al.   Nature Reviews Gastroenterology & Hepatology

Impacts of Pretransplant Infections on Clinical Outcomes of Patients with Acute-On-Chronic Liver Failure Who Received Living-Donor Liver Transplantation

(2013) Kuo-Hua Lin et al.   PLoS One

Transplantation of mesenchymal stem cells for the treatment of liver diseases, is there enough evidence?

(2013) Raphael P.H. Meier et al.   Stem Cell Research

Experience of Combined Liver-Kidney Transplantation for Acute-on-Chronic Liver Failure Patients With Renal Dysfunction

(2013) T. Xing et al.   TRANSPLANTATION PROCEEDINGS

Granulocyte-colony stimulating factor therapy improves survival in patients with hepatitis B virus-associated acute-on-chronic liver failure

(2013) Xue-Zhang Duan   WORLD JOURNAL OF GASTROENTEROLOGY

Artificial liver support devices as treatment option for liver failure

(2012) Frederik Nevens et al.   BEST PRACTICE & RESEARCH IN CLINICAL GASTROENTEROLOGY

The Challenges of Providing Renal Replacement Therapy in Decompensated Liver Cirrhosis

(2012) Thomas A. Gonwa et al.   BLOOD PURIFICATION

Improved survival ratios correlate with myeloid dendritic cell restoration in acute-on-chronic liver failure patients receiving methylprednisolone therapy

(2012) Juan Zhao et al.   Cellular & Molecular Immunology

Alcohol Metabolism

(2012) Arthur I. Cederbaum   Clinics in Liver Disease

Corticosteroid Plus Pentoxifylline Is Not Better than Corticosteroid Alone for Improving Survival in Severe Alcoholic Hepatitis (COPE Trial)

(2012) Sandeep Singh Sidhu et al.   DIGESTIVE DISEASES AND SCIENCES

Effects of Fractionated Plasma Separation and Adsorption on Survival in Patients With Acute-on-Chronic Liver Failure

(2012) Andreas Kribben et al.   GASTROENTEROLOGY

Liver progenitor cell markers correlate with liver damage and predict short-term mortality in patients with alcoholic hepatitis

(2012) Pau Sancho-Bru et al.   HEPATOLOGY

Extracorporeal albumin dialysis with the molecular adsorbent recirculating system in acute-on-chronic liver failure: The RELIEF trial

(2012) Rafael Bañares et al.   HEPATOLOGY

Kinetics of peripheral hepatitis B virus-specific CD8+ T cells in patients with onset of viral reactivation

(2012) Jun Aoki et al.   JOURNAL OF GASTROENTEROLOGY

Increased number and function of endothelial progenitor cells stimulate angiogenesis by resident liver sinusoidal endothelial cells (SECs) in cirrhosis through paracrine factors

(2012) Savneet Kaur et al.   JOURNAL OF HEPATOLOGY

Acute-on chronic liver failure

(2012) Rajiv Jalan et al.   JOURNAL OF HEPATOLOGY

Hepatitis E

(2012) Nassim Kamar et al.   LANCET

Risk factors and a predictive model for acute hepatic failure after transcatheter arterial chemoembolization in patients with hepatocellular carcinoma

(2012) Yang Won Min et al.   LIVER INTERNATIONAL

Bridging the gap: Advances in artificial liver support

(2012) Scott L. Nyberg   LIVER TRANSPLANTATION

Macrophage-derived Wnt opposes Notch signaling to specify hepatic progenitor cell fate in chronic liver disease

(2012) Luke Boulter et al.   NATURE MEDICINE

Downgrading MELD Improves the Outcomes after Liver Transplantation in Patients with Acute-on-Chronic Hepatitis B Liver Failure

(2012) Qi Ling et al.   PLoS One

Liver Replacement Therapy

(2012) Giovanni Tritto et al.   SEMINARS IN RESPIRATORY AND CRITICAL CARE MEDICINE

Angiogenesis is crucial for liver regeneration after partial hepatectomy

(2012) Yugo Uda et al.   SURGERY

Hepatic stellate cells are involved in the pathogenesis of acute-on-chronic liver failure (ACLF)

(2012) Archana Rastogi et al.   VIRCHOWS ARCHIV

Human Mesenchymal Stem Cell Transfusion Is Safe and Improves Liver Function in Acute-on-Chronic Liver Failure Patients

(2012) Ming Shi et al.   Stem Cells Translational Medicine

Acute-on-chronic liver failure: concept, natural history, and prognosis

(2011) Jody C Olson et al.   Current Opinion in Critical Care

Clinical profile and predictors of mortality in patients of acute-on-chronic liver failure

(2011) Hitendra Garg et al.   DIGESTIVE AND LIVER DISEASE

Peripheral T regulatory cells and cytokines in hepatitis E infection

(2011) A. S. Tripathy et al.   EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES

Alcoholic Liver Disease: Pathogenesis and New Therapeutic Targets

(2011) Bin Gao et al.   GASTROENTEROLOGY

Granulocyte Colony–Stimulating Factor Mobilizes CD34+ Cells and Improves Survival of Patients With Acute-on-Chronic Liver Failure

(2011) Vishal Garg et al.   GASTROENTEROLOGY

Role of stem cell factor and granulocyte colony-stimulating factor in remodeling during liver regeneration

(2011) Fanyin Meng et al.   HEPATOLOGY

In vitro steroid resistance correlates with outcome in severe alcoholic hepatitis

(2011) A.J. di Mambro et al.   HEPATOLOGY

A polymorphism in TIM1 is associated with susceptibility to severe hepatitis A virus infection in humans

(2011) Hye Young Kim et al.   JOURNAL OF CLINICAL INVESTIGATION

Late evening snack: Exploiting a period of anabolic opportunity in cirrhosis

(2011) Cynthia D Tsien et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Toll-like receptor (TLR) 2 promoter and intron 2 polymorphisms are associated with increased risk for spontaneous bacterial peritonitis in liver cirrhosis

(2011) H.D. Nischalke et al.   JOURNAL OF HEPATOLOGY

Pathways of liver injury in alcoholic liver disease

(2011) Herbert Tilg et al.   JOURNAL OF HEPATOLOGY

The role of liver biopsy in the diagnosis and prognosis of patients with acute deterioration of alcoholic cirrhosis

(2011) Rajeshwar P. Mookerjee et al.   JOURNAL OF HEPATOLOGY

The difficulties of managing severe hepatitis B virus reactivation

(2011) Bruno Roche et al.   LIVER INTERNATIONAL

Early Liver Transplantation for Severe Alcoholic Hepatitis

(2011) Philippe Mathurin et al.   NEW ENGLAND JOURNAL OF MEDICINE

Acute-on-Chronic Liver Failure Before Liver Transplantation: Impact on Posttransplant Outcomes

(2011) Ranjeeta Bahirwani et al.   TRANSPLANTATION

The Ratio of Th-17 to Treg Cells is Associated with Survival of Patients with Acute-on-Chronic Hepatitis B Liver Failure

(2011) Song Zhai et al.   VIRAL IMMUNOLOGY

Liver histology as predictor of outcome in patients with acute-on-chronic liver failure (ACLF)

(2011) Archana Rastogi et al.   VIRCHOWS ARCHIV

Acute-on-chronic liver failure: current concepts on definition, pathogenesis, clinical manifestations and potential therapeutic interventions

(2011) Wim Laleman et al.   Expert Review of Gastroenterology & Hepatology

Single-Center Experience With Drug-Induced Liver Injury From India: Causes, Outcome, Prognosis and Predictors of Mortality

(2010) Harshad Devarbhavi et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Inflammation 2010: New Adventures of an Old Flame

(2010) Ruslan Medzhitov   CELL

Update on clinical experience with AMD3100, an SDF-1/CXCL12–CXCR4 inhibitor, in mobilization of hematopoietic stem and progenitor cells

(2010) Iskra Pusic et al.   CURRENT OPINION IN HEMATOLOGY

Pentoxifylline Does Not Decrease Short-term Mortality but Does Reduce Complications in Patients With Advanced Cirrhosis

(2010) Didier Lebrec et al.   GASTROENTEROLOGY

Acute-on-chronic liver failure: an early biopsy is essential?

(2010) R. Jalan et al.   GUT

Corticosteroids improve short-term survival in patients with severe alcoholic hepatitis: meta-analysis of individual patient data

(2010) P. Mathurin et al.   GUT

Early features of acute-on-chronic alcoholic liver failure: a prospective cohort study

(2010) A. Katoonizadeh et al.   GUT

Bacterial DNA translocation is associated with systemic circulatory abnormalities and intrahepatic endothelial dysfunction in patients with cirrhosis

(2010) Pablo Bellot et al.   HEPATOLOGY

Enteric dysbiosis associated with a mouse model of alcoholic liver disease

(2010) Arthur W. Yan et al.   HEPATOLOGY

Drug-induced acute liver failure: Results of a U.S. multicenter, prospective study

(2010) Adrian Reuben et al.   HEPATOLOGY

Early predictors of corticosteroid treatment failure in icteric presentations of autoimmune hepatitis

(2010) Andrew D. Yeoman et al.   HEPATOLOGY

Tenofovir improves the outcome in patients with spontaneous reactivation of hepatitis B presenting as acute-on-chronic liver failure

(2010) Hitendra Garg et al.   HEPATOLOGY

Comparison of effects of hepatitis E or A viral superinfection in patients with chronic hepatitis B

(2010) Xiaohong Zhang et al.   Hepatology International

Severity of the compensatory anti-inflammatory response determined by monocyte HLA-DR expression may assist outcome prediction in cirrhosis

(2010) Philip A. Berry et al.   INTENSIVE CARE MEDICINE

Endoplasmic reticulum stress in liver disease

(2010) Harmeet Malhi et al.   JOURNAL OF HEPATOLOGY

Bone marrow-derived stem cells in liver repair: 10 years down the line

(2010) Eleanor S. Gilchrist et al.   LIVER TRANSPLANTATION

Intestinal permeability in patients with chronic liver diseases: Its relationship with the aetiology and the entity of liver damage

(2009) Rita Cariello et al.   DIGESTIVE AND LIVER DISEASE

Infection in Patients With Severe Alcoholic Hepatitis Treated With Steroids: Early Response to Therapy Is the Key Factor

(2009) Alexandre Louvet et al.   GASTROENTEROLOGY

Diagnosis, management and prevention of drug-induced liver injury

(2009) S Verma et al.   GUT

Liver transplantation for acute-on-chronic liver failure

(2009) Albert C. Chan et al.   Hepatology International

Viral Load, Antibody Titers and Recombinant Open Reading Frame 2 Protein-Induced Th1/Th2 Cytokines and Cellular Immune Responses in Self-Limiting and Fulminant Hepatitis E

(2009) S. Saravanabalaji et al.   INTERVIROLOGY

Influential factors of prognosis in lamivudine treatment for patients with acute-on-chronic hepatitis B liver failure

(2009) Li-Jie Sun et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Infection and inflammation in liver failure: Two sides of the same coin

(2009) Raza Malik et al.   JOURNAL OF HEPATOLOGY

Clinical features and predictors of outcome in acute hepatitis A and hepatitis E virus hepatitis on cirrhosis

(2009) Yellapu Radha Krishna et al.   LIVER INTERNATIONAL

Alcoholic Hepatitis

(2009) Michael R. Lucey et al.   NEW ENGLAND JOURNAL OF MEDICINE

Continuous Renal Replacement Therapies in Patients with Liver Disease

(2009) Andrew Davenport   SEMINARS IN DIALYSIS

Pentoxifylline versus prednisolone for severe alcoholic hepatitis: A randomized controlled trial

(2009) Binay Krishna De et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Mycophenolate Mofetil as Second Line Therapy in Autoimmune Hepatitis?

(2008) Elke M. Hennes et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Recombinant human hepatocyte growth factor for liver failure

(2008) Yao-Li Cui et al.   Contemporary Clinical Trials

Hemodynamic Studies in Acute-on-Chronic Liver Failure

(2008) Ashish Kumar et al.   DIGESTIVE DISEASES AND SCIENCES

Dynamic Programmed Death 1 Expression by Virus-Specific CD8 T Cells Correlates With the Outcome of Acute Hepatitis B

(2008) Zheng Zhang et al.   GASTROENTEROLOGY

Toll‐like receptors and adaptor molecules in liver disease: Update

(2008) Ekihiro Seki et al.   HEPATOLOGY

Acute-on-chronic liver failure: consensus recommendations of the Asian Pacific Association for the study of the liver (APASL)

(2008) Shiv Kumar Sarin et al.   Hepatology International

Hepatitis E virus as an etiology of acute exacerbation of previously unrecognized asymptomatic patients with hepatitis B virus-related chronic liver disease

(2008) Manoj Kumar et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Severe dendritic cell perturbation is actively involved in the pathogenesis of acute-on-chronic hepatitis B liver failure

(2008) Zheng Zhang et al.   JOURNAL OF HEPATOLOGY