In situ profiling reveals metabolic alterations in the tumor microenvironment of ovarian cancer after chemotherapy

Exploiting metabolic vulnerabilities after anti-VEGF antibody therapy in ovarian cancer

(2023) Deanna Glassman et al.   iScience

Serine metabolism remodeling after platinum-based chemotherapy identifies vulnerabilities in a subgroup of resistant ovarian cancers

(2022) Tom Van Nyen et al.   Nature Communications

Targeting Phosphatidylserine Enhances the Anti-tumor Response to Tumor-Directed Radiation Therapy in a Preclinical Model of Melanoma

(2021) Sadna Budhu et al.   Cell Reports

mTORC1 activity regulates post-translational modifications of glycine decarboxylase to modulate glycine metabolism and tumorigenesis

(2021) Rui Liu et al.   Nature Communications

Metabolic Plasticity in Chemotherapy Resistance

(2020) Maria Andrea Desbats et al.   Frontiers in Oncology

Molecular Analysis of Clinically Defined Subsets of High-Grade Serous Ovarian Cancer

(2020) Sanghoon Lee et al.   Cell Reports

Induction of a Timed Metabolic Collapse to Overcome Cancer Chemoresistance

(2020) Nick van Gastel et al.   Cell Metabolism

Allosteric inhibition of MTHFR prevents futile SAM cycling and maintains nucleotide pools in one carbon metabolism

(2020) Muskan Bhatia et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Glycine decarboxylase is a transcriptional target of MYCN required for neuroblastoma cell proliferation and tumorigenicity

(2019) Ahmet Alptekin et al.   ONCOGENE

As Extracellular Glutamine Levels Decline, Asparagine Becomes an Essential Amino Acid

(2018) Natalya N. Pavlova et al.   Cell Metabolism

Inhibiting Glycine Decarboxylase Suppresses Pyruvate-to-Lactate Metabolism in Lung Cancer Cells

(2018) Chern Chiuh Woo et al.   Frontiers in Oncology

Laparoscopic Surgical Algorithm to Triage the Timing of Tumor Reductive Surgery in Advanced Ovarian Cancer

(2018) Nicole D. Fleming et al.   OBSTETRICS AND GYNECOLOGY

Concordance of a laparoscopic scoring algorithm with primary surgery findings in advanced stage ovarian cancer

(2018) Jean M. Hansen et al.   GYNECOLOGIC ONCOLOGY

Targeting Stromal Glutamine Synthetase in Tumors Disrupts Tumor Microenvironment-Regulated Cancer Cell Growth

(2016) Lifeng Yang et al.   Cell Metabolism

Cancer death rates in US congressional districts

(2015) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Spatially Resolved Metabolic Phenotyping of Breast Cancer by Desorption Electrospray Ionization Mass Spectrometry

(2015) S. Guenther et al.   CANCER RESEARCH

Regularization Paths for Generalized Linear Models via Coordinate Descent

(2015) Jerome Friedman et al.   Journal of Statistical Software

Acid-Mediated Tumor Proteolysis: Contribution of Cysteine Cathepsins

(2015) Jennifer M Rothberg et al.   NEOPLASIA

Asparagine Plays a Critical Role in Regulating Cellular Adaptation to Glutamine Depletion

(2014) Ji Zhang et al.   MOLECULAR CELL

Functional polarization of tumour-associated macrophages by tumour-derived lactic acid

(2014) Oscar R. Colegio et al.   NATURE

Molecular assessment of surgical-resection margins of gastric cancer by mass-spectrometric imaging

(2014) L. S. Eberlin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Analysis of Tissue Specimens by Matrix-Assisted Laser Desorption/Ionization Imaging Mass Spectrometry in Biological and Clinical Research

(2013) Jeremy L. Norris et al.   CHEMICAL REVIEWS

Glycine Decarboxylase Activity Drives Non-Small Cell Lung Cancer Tumor-Initiating Cells and Tumorigenesis

(2012) Wen Cai Zhang et al.   CELL

Implementing an online tool for genome-wide validation of survival-associated biomarkers in ovarian-cancer using microarray data from 1287 patients

(2012) Balázs Győrffy et al.   ENDOCRINE-RELATED CANCER

A multimodal mass spectrometry imaging approach for the study of musculoskeletal tissues

(2012) Sanaullah Chughtai et al.   INTERNATIONAL JOURNAL OF MASS SPECTROMETRY

Data quality in tissue analysis using desorption electrospray ionization

(2011) Allison L. Dill et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Sparse PLS discriminant analysis: biologically relevant feature selection and graphical displays for multiclass problems

(2011) Kim-Anh Lê Cao et al.   BMC BIOINFORMATICS

Classifying Human Brain Tumors by Lipid Imaging with Mass Spectrometry

(2011) L. S. Eberlin et al.   CANCER RESEARCH

Lactate Influx through the Endothelial Cell Monocarboxylate Transporter MCT1 Supports an NF- B/IL-8 Pathway that Drives Tumor Angiogenesis

(2011) F. Vegran et al.   CANCER RESEARCH

Adipocytes promote ovarian cancer metastasis and provide energy for rapid tumor growth

(2011) Kristin M Nieman et al.   NATURE MEDICINE

Compartmentalization of Mammalian Folate-Mediated One-Carbon Metabolism

(2010) Anne S. Tibbetts et al.   Annual Review of Nutrition

The Glycerophospho Metabolome and Its Influence on Amino Acid Homeostasis Revealed by Brain Metabolomics of GDE1(−/−) Mice

(2010) Florian Kopp et al.   CHEMISTRY & BIOLOGY