Resolving macromolecular structures from electron cryo-tomography data using subtomogram averaging in RELION

Cryo-focused-ion-beam applications in structural biology

(2015) Alexander Rigort et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Single-Particle Cryo-EM at Crystallographic Resolution

(2015) Yifan Cheng   CELL

Advances in Single-Particle Electron Cryomicroscopy Structure Determination applied to Sub-tomogram Averaging

(2015) Tanmay A.M. Bharat et al.   STRUCTURE

How cryo-EM is revolutionizing structural biology

(2015) Xiao-chen Bai et al.   TRENDS IN BIOCHEMICAL SCIENCES

Structure of the native Sec61 protein-conducting channel

(2015) Stefan Pfeffer et al.   Nature Communications

Structure of the immature HIV-1 capsid in intact virus particles at 8.8 Å resolution

(2014) Florian K. M. Schur et al.   NATURE

A 3D cellular context for the macromolecular world

(2014) Ardan Patwardhan et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Cryo-electron microscopy of tubular arrays of HIV-1 Gag resolves structures essential for immature virus assembly

(2014) T. A. M. Bharat et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Beam-induced motion correction for sub-megadalton cryo-EM particles

(2014) Sjors HW Scheres   eLife

Structural biology in situ—the potential of subtomogram averaging

(2013) John AG Briggs   CURRENT OPINION IN STRUCTURAL BIOLOGY

Projection-based volume alignment

(2013) Lingbo Yu et al.   JOURNAL OF STRUCTURAL BIOLOGY

Quantifying the local resolution of cryo-EM density maps

(2013) Alp Kucukelbir et al.   NATURE METHODS

High-resolution noise substitution to measure overfitting and validate resolution in 3D structure determination by single particle electron cryomicroscopy

(2013) Shaoxia Chen et al.   ULTRAMICROSCOPY

Unraveling the structure of membrane proteins in situ by transfer function corrected cryo-electron tomography

(2012) Matthias Eibauer et al.   JOURNAL OF STRUCTURAL BIOLOGY

Dynamo: A flexible, user-friendly development tool for subtomogram averaging of cryo-EM data in high-performance computing environments

(2012) Daniel Castaño-Díez et al.   JOURNAL OF STRUCTURAL BIOLOGY

RELION: Implementation of a Bayesian approach to cryo-EM structure determination

(2012) Sjors H.W. Scheres   JOURNAL OF STRUCTURAL BIOLOGY

Structure of the immature retroviral capsid at 8 Å resolution by cryo-electron microscopy

(2012) Tanmay A. M. Bharat et al.   NATURE

Prevention of overfitting in cryo-EM structure determination

(2012) Sjors H W Scheres et al.   NATURE METHODS

Protein Secondary Structure Determination by Constrained Single-Particle Cryo-Electron Tomography

(2012) Alberto Bartesaghi et al.   STRUCTURE

Outcome of the First Electron Microscopy Validation Task Force Meeting

(2012) Richard Henderson et al.   STRUCTURE

A Bayesian View on Cryo-EM Structure Determination

(2011) Sjors H.W. Scheres   JOURNAL OF MOLECULAR BIOLOGY

PyTom: A python-based toolbox for localization of macromolecules in cryo-electron tomograms and subtomogram analysis

(2011) Thomas Hrabe et al.   JOURNAL OF STRUCTURAL BIOLOGY

Fast tomographic reconstruction on multicore computers

(2010) J. I. Agulleiro et al.   BIOINFORMATICS

Electron Cryotomography of Tula Hantavirus Suggests a Unique Assembly Paradigm for Enveloped Viruses

(2010) J. T. Huiskonen et al.   JOURNAL OF VIROLOGY

Structure and assembly of immature HIV

(2009) J. A. G. Briggs et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA