Growth and division of active droplets provides a model for protocells

Phase Separation by Low Complexity Domains Promotes Stress Granule Assembly and Drives Pathological Fibrillization

(2015) Amandine Molliex et al.   CELL

In vitro gene expression within membrane-free coacervate protocells

(2015) T.-Y. Dora. Tang et al.   CHEMICAL COMMUNICATIONS

Formation and Maturation of Phase-Separated Liquid Droplets by RNA-Binding Proteins

(2015) Yuan Lin et al.   MOLECULAR CELL

Suppression of Ostwald ripening in active emulsions

(2015) David Zwicker et al.   PHYSICAL REVIEW E

The disordered P granule protein LAF-1 drives phase separation into droplets with tunable viscosity and dynamics

(2015) Shana Elbaum-Garfinkle et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Liquid-Liquid Phase Separation in Biology

(2014) Anthony A. Hyman et al.   Annual Review of Cell and Developmental Biology

Assemblages: Functional units formed by cellular phase separation

(2014) Jeffrey A. Toretsky et al.   JOURNAL OF CELL BIOLOGY

The RNA World: molecular cooperation at the origins of life

(2014) Paul G. Higgs et al.   NATURE REVIEWS GENETICS

Spontaneous Division and Motility in Active Nematic Droplets

(2014) Luca Giomi et al.   PHYSICAL REVIEW LETTERS

Centrosomes are autocatalytic droplets of pericentriolar material organized by centrioles

(2014) David Zwicker et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Energy at life's origin

(2014) W. F. Martin et al.   SCIENCE

Enhanced transcription rates in membrane-free protocells formed by coacervation of cell lysate

(2013) E. Sokolova et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Getting RNA and Protein in Phase

(2012) Stephanie C. Weber et al.   CELL

Stabilization and enhanced reactivity of actinorhodin polyketide synthase minimal complex in polymer–nucleotide coacervate droplets

(2012) John Crosby et al.   CHEMICAL COMMUNICATIONS

Early self-reproduction, the emergence of division mechanisms in protocells

(2012) Giovanni Murtas   Molecular BioSystems

Hydrogen, metals, bifurcating electrons, and proton gradients: The early evolution of biological energy conservation

(2011) William F. Martin   FEBS LETTERS

Peptide–nucleotide microdroplets as a step towards a membrane-free protocell model

(2011) Shogo Koga et al.   Nature Chemistry

Soft active aggregates: mechanics, dynamics and self-assembly of liquid-like intracellular protein bodies

(2011) Clifford P. Brangwynne   Soft Matter

The unstable and expanding interface between reacting liquids: theoretical interpretation of negative surface tension

(2011) A. Z. Patashinski et al.   Soft Matter

Self-Division of Macroscopic Droplets: Partitioning of Nanosized Cargo into Nanoscale Micelles

(2010) Kevin P. Browne et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Germline P Granules Are Liquid Droplets That Localize by Controlled Dissolution/Condensation

(2009) C. P. Brangwynne et al.   SCIENCE