Comparison of Cas9 activators in multiple species

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Delivery and Specificity of CRISPR/Cas9 Genome Editing Technologies for Human Gene Therapy

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The New State of the Art: Cas9 for Gene Activation and Repression

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Epigenome editing by a CRISPR-Cas9-based acetyltransferase activates genes from promoters and enhancers

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Unraveling CRISPR-Cas9 genome engineering parameters via a library-on-library approach

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Highly efficient Cas9-mediated transcriptional programming

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Beyond editing: repurposing CRISPR–Cas9 for precision genome regulation and interrogation

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In VivoTranscriptional Activation Using CRISPR/Cas9 inDrosophila

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A Protein-Tagging System for Signal Amplification in Gene Expression and Fluorescence Imaging

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Genome-Scale CRISPR-Mediated Control of Gene Repression and Activation

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Development and Applications of CRISPR-Cas9 for Genome Engineering

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Rational design of highly active sgRNAs for CRISPR-Cas9–mediated gene inactivation

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Optimized CRISPR/Cas tools for efficient germline and somatic genome engineering in Drosophila

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voom: precision weights unlock linear model analysis tools for RNA-seq read counts

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A CRISPR/Cas9-Based System for Reprogramming Cell Lineage Specification

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CRISPR-Mediated Modular RNA-Guided Regulation of Transcription in Eukaryotes

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Multiplexed activation of endogenous genes by CRISPR-on, an RNA-guided transcriptional activator system

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The Mediator complex and transcription regulation

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CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering

(2013) Prashant Mali et al.   NATURE BIOTECHNOLOGY

RNA-guided gene activation by CRISPR-Cas9–based transcription factors

(2013) Pablo Perez-Pinera et al.   NATURE METHODS

Robust, synergistic regulation of human gene expression using TALE activators

(2013) Morgan L Maeder et al.   NATURE METHODS

CRISPR RNA–guided activation of endogenous human genes

(2013) Morgan L Maeder et al.   NATURE METHODS

Synergistic and tunable human gene activation by combinations of synthetic transcription factors

(2013) Pablo Perez-Pinera et al.   NATURE METHODS

RNA-Guided Human Genome Engineering via Cas9

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Multiplex Genome Engineering Using CRISPR/Cas Systems

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Transcription factors: from enhancer binding to developmental control

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A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

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RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome

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The Streptococcus thermophilus CRISPR/Cas system provides immunity in Escherichia coli

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The CRISPR/Cas bacterial immune system cleaves bacteriophage and plasmid DNA

(2010) Josiane E. Garneau et al.   NATURE

High Local Concentration: A Fundamental Strategy of Life

(2009) Stefan Oehler et al.   JOURNAL OF MOLECULAR BIOLOGY

Enzymatic assembly of DNA molecules up to several hundred kilobases

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