An AMP-activated protein kinase–stabilizing peptide ameliorates adipose tissue wasting in cancer cachexia in mice

Lipolytic and thermogenic depletion of adipose tissue in cancer cachexia

(2016) Maria Tsoli et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Association of nicotinamide-N-methyltransferase mRNA expression in human adipose tissue and the plasma concentration of its product, 1-methylnicotinamide, with insulin resistance

(2015) Aimo Kannt et al.   DIABETOLOGIA

Alternative Mechanism for White Adipose Tissue Lipolysis after Thermal Injury

(2015) Li Diao et al.   MOLECULAR MEDICINE

A Switch from White to Brown Fat Increases Energy Expenditure in Cancer-Associated Cachexia

(2014) Michele Petruzzelli et al.   Cell Metabolism

The energy balance in cancer cachexia revisited

(2014) Judith de Vos-Geelen et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Tumour-derived PTH-related protein triggers adipose tissue browning and cancer cachexia

(2014) Serkan Kir et al.   NATURE

Cancer Cachexia Syndrome: Pathogenesis, Diagnosis, and New Therapeutic Options

(2014) Patrizia Mondello et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Depletion of White Adipose Tissue in Cancer Cachexia Syndrome Is Associated with Inflammatory Signaling and Disrupted Circadian Regulation

(2014) Maria Tsoli et al.   PLoS One

Diverse effect of WWOX overexpression in HT29 and SW480 colon cancer cell lines

(2014) Magdalena Nowakowska et al.   TUMOR BIOLOGY

Transcriptional Cofactor TBLR1 Controls Lipid Mobilization in White Adipose Tissue

(2013) Maria Rohm et al.   Cell Metabolism

TSC22D4 is a molecular output of hepatic wasting metabolism

(2013) Allan Jones et al.   EMBO Molecular Medicine

Single phosphorylation sites in Acc1 and Acc2 regulate lipid homeostasis and the insulin-sensitizing effects of metformin

(2013) Morgan D Fullerton et al.   NATURE MEDICINE

Chronic AICAR-induced AMP-kinase activation regulates adipocyte lipolysis in a time-dependent and fat depot-specific manner in rats

(2012) Mandeep P. Gaidhu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

CIDE Proteins and Lipid Metabolism

(2012) Li Xu et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Accelerated muscle and adipose tissue loss may predict survival in pancreatic cancer patients: the relationship with diabetes and anaemia

(2012) Katie M. Di Sebastiano et al.   BRITISH JOURNAL OF NUTRITION

Cancer Cachexia: Mediators, Signaling, and Metabolic Pathways

(2012) Kenneth C.H. Fearon et al.   Cell Metabolism

Adipose tissue-derived factors as potential biomarkers in cachectic cancer patients

(2012) M.L. Batista et al.   CYTOKINE

AMPK: a nutrient and energy sensor that maintains energy homeostasis

(2012) D. Grahame Hardie et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Cachexia but not obesity worsens the postoperative outcome after pancreatoduodenectomy in pancreatic cancer

(2012) Thomas Pausch et al.   SURGERY

Homocysteine suppresses lipolysis in adipocytes by activating the AMPK pathway

(2011) Zhigang Wang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Cancer cachexia: A systematic literature review of items and domains associated with involuntary weight loss in cancer

(2011) David Blum et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Definition and classification of cancer cachexia: an international consensus

(2011) Kenneth Fearon et al.   LANCET ONCOLOGY

A guide to analysis of mouse energy metabolism

(2011) Matthias H Tschöp et al.   NATURE METHODS

Adipose Triglyceride Lipase Contributes to Cancer-Associated Cachexia

(2011) S. K. Das et al.   SCIENCE

Cancer Cachexia: Traditional Therapies and Novel Molecular Mechanism-Based Approaches to Treatment

(2010) Nagi B. Kumar et al.   CURRENT TREATMENT OPTIONS IN ONCOLOGY

AMP-activated Protein Kinase  2 Subunit Is Required for the Preservation of Hepatic Insulin Sensitivity by n-3 Polyunsaturated Fatty Acids

(2010) T. Jelenik et al.   DIABETES

Cyclooxygenase-2 Controls Energy Homeostasis in Mice by de Novo Recruitment of Brown Adipocytes

(2010) A. Vegiopoulos et al.   SCIENCE

Biguanides and thiazolidinediones inhibit stimulated lipolysis in human adipocytes through activation of AMP-activated protein kinase

(2009) O. Bourron et al.   DIABETOLOGIA

PKA phosphorylates and inactivates AMPKα to promote efficient lipolysis

(2009) Nabil Djouder et al.   EMBO JOURNAL

AMPK β1 Deletion Reduces Appetite, Preventing Obesity and Hepatic Insulin Resistance

(2009) Nicolas Dzamko et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A placebo-controlled, double-blind trial of infliximab for cancer-associated weight loss in elderly and/or poor performance non-small cell lung cancer patients (N01C9)

(2009) Aminah Jatoi et al.   LUNG CANCER

Cachexia: Common, Deadly, With an Urgent Need for Precise Definition and New Therapies

(2008) Mitja Lainscak et al.   AMERICAN JOURNAL OF CARDIOLOGY

Lipolysis-Not inflammation, cell death, or lipogenesis-Is involved in adipose tissue loss in cancer cachexia

(2008) Mikael Rydén et al.   CANCER

Evidence for an Important Role of CIDEA in Human Cancer Cachexia

(2008) J. Laurencikiene et al.   CANCER RESEARCH

Identification of White Adipocyte Progenitor Cells In Vivo

(2008) Matthew S. Rodeheffer et al.   CELL

Intravenous AICAR administration reduces hepatic glucose output and inhibits whole body lipolysis in type 2 diabetic patients

(2008) H. Boon et al.   DIABETOLOGIA

Downregulation of AMP-activated protein kinase by Cidea-mediated ubiquitination and degradation in brown adipose tissue

(2008) Jingzong Qi et al.   EMBO JOURNAL

Nuclear receptor cofactor receptor interacting protein 140 controls hepatic triglyceride metabolism during wasting in mice

(2008) Mauricio Berriel Diaz et al.   HEPATOLOGY

AMP-activated Protein Kinase Is Activated as a Consequence of Lipolysis in the Adipocyte

(2008) Marie-Soleil Gauthier et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Prolonged AICAR-induced AMP-kinase activation promotes energy dissipation in white adipocytes: novel mechanisms integrating HSL and ATGL

(2008) Mandeep P. Gaidhu et al.   JOURNAL OF LIPID RESEARCH