CIDE Proteins and Lipid Metabolism

Expression of apolipoprotein C-III in McA-RH7777 cells enhances VLDL assembly and secretion under lipid-rich conditions

(2017) Meenakshi Sundaram et al.   JOURNAL OF LIPID RESEARCH

Cidea promotes hepatic steatosis by sensing dietary fatty acids

(2012) Linkang Zhou et al.   HEPATOLOGY

Cidea is an essential transcriptional coactivator regulating mammary gland secretion of milk lipids

(2012) Wenshan Wang et al.   NATURE MEDICINE

Phosphatidylcholine Synthesis for Lipid Droplet Expansion Is Mediated by Localized Activation of CTP:Phosphocholine Cytidylyltransferase

(2011) Natalie Krahmer et al.   Cell Metabolism

Missense Mutation inAPOC3within the C-terminal Lipid Binding Domain of Human ApoC-III Results in Impaired Assembly and Secretion of Triacylglycerol-rich Very Low Density Lipoproteins

(2011) Wen Qin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Fsp27 promotes lipid droplet growth by lipid exchange and transfer at lipid droplet contact sites

(2011) Jingyi Gong et al.   JOURNAL OF CELL BIOLOGY

Insulin Resistance Is a Sufficient Basis for Hyperandrogenism in Lipodystrophic Women with Polycystic Ovarian Syndrome

(2011) Andreea O. Lungu et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

FSP27 Promotes Lipid Droplet Clustering and Then Fusion to Regulate Triglyceride Accumulation

(2011) Srikarthika Jambunathan et al.   PLoS One

A Role for Phosphatidic Acid in the Formation of “Supersized” Lipid Droplets

(2011) Weihua Fei et al.   PLoS Genetics

Apolipoprotein B100 biogenesis: a complex array of intracellular mechanisms regulating folding, stability, and lipoprotein assemblyThis paper is one of a selection of papers published in this special issue entitled “Canadian Society of Biochemistry, Molecular & Cellular Biology 52nd Annual Meeting — Protein Folding: Principles and Diseases” and has undergone the Journal's usual peer review process.

(2010) Angela C. Rutledge et al.   Biochemistry and Cell Biology

Control of cholesterol biosynthesis, uptake and storage in hepatocytes by Cideb

(2010) John Zhong Li et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Cellular Lipid Droplets and Hepatitis C Virus Life Cycle

(2010) Masayoshi Fukasawa   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Regulation of gene expression by FSP27 in white and brown adipose tissue

(2010) De Li et al.   BMC GENOMICS

Identification of lipid droplet-associated proteins in the formation of macrophage-derived foam cells using microarrays

(2010) Li   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Peroxisome Proliferator-activated Receptor-γ Coactivator-1α (PGC-1α) Stimulates VLDL Assembly through Activation of Cell Death-inducing DFFA-like Effector B (CideB)

(2010) Zhouji Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of fat specific protein 27 by isoproterenol and TNF-α to control lipolysis in murine adipocytes

(2010) Srijana Ranjit et al.   JOURNAL OF LIPID RESEARCH

Identification of the lipid droplet targeting domain of the Cidea protein

(2010) Jennifer L. Christianson et al.   JOURNAL OF LIPID RESEARCH

Absence of adipose differentiation related protein upregulates hepatic VLDL secretion, relieves hepatosteatosis, and improves whole body insulin resistance in leptin-deficient mice

(2010) Benny Hung-Junn Chang et al.   JOURNAL OF LIPID RESEARCH

Which CIDE are you on? Apoptosis and energy metabolism

(2010) Tomo Yonezawa et al.   Molecular BioSystems

Recent progress in understanding protein and lipid factors affecting hepatic VLDL assembly and secretion

(2010) Meenakshi Sundaram et al.   Nutrition & Metabolism

Functional analysis of FSP27 protein regions for lipid droplet localization, caspase-dependent apoptosis, and dimerization with CIDEA

(2009) Kun Liu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Modulation of myocellular fat stores: lipid droplet dynamics in health and disease

(2009) Ruth C. R. Meex et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

A Class of Dynamin-like GTPases Involved in the Generation of the Tubular ER Network

(2009) Junjie Hu et al.   CELL

Cideb, an ER- and Lipid Droplet-Associated Protein, Mediates VLDL Lipidation and Maturation by Interacting with Apolipoprotein B

(2009) Jing Ye et al.   Cell Metabolism

CIDE proteins and metabolic disorders

(2009) Jingyi Gong et al.   CURRENT OPINION IN LIPIDOLOGY

Partial lipodystrophy and insulin resistant diabetes in a patient with a homozygous nonsense mutation inCIDEC

(2009) Oscar Rubio-Cabezas et al.   EMBO Molecular Medicine

Homotypic fusion of ER membranes requires the dynamin-like GTPase Atlastin

(2009) Genny Orso et al.   NATURE

Hepatic Expression of Cell Death–inducing DFFA-like Effector C in Obese Subjects Is Reduced by Marked Weight Loss

(2009) Angela M. Hall et al.   Obesity

Lipid droplets as dynamic organelles connecting storage and efflux of lipids

(2008) Sven-Olof Olofsson et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Hepatic Steatosis in Leptin-Deficient Mice Is Promoted by the PPARγ Target Gene Fsp27

(2008) Kimihiko Matsusue et al.   Cell Metabolism

Consequences of Lipid Droplet Coat Protein Downregulation in Liver Cells: Abnormal Lipid Droplet Metabolism and Induction of Insulin Resistance

(2008) M. Bell et al.   DIABETES

Regulation of ApoB Secretion by the Low Density Lipoprotein Receptor Requires Exit from the Endoplasmic Reticulum and Interaction with ApoE or ApoB

(2008) Daniel A. Blasiole et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Fat-specific Protein 27 Regulates Storage of Triacylglycerol

(2008) Pernille Keller et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Fld1p, a functional homologue of human seipin, regulates the size of lipid droplets in yeast

(2008) Weihua Fei et al.   JOURNAL OF CELL BIOLOGY

Functional genomic screen reveals genes involved in lipid-droplet formation and utilization

(2008) Yi Guo et al.   NATURE

Synaptic vesicle fusion

(2008) Josep Rizo et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Membrane fusion

(2008) William Wickner et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Cidea is associated with lipid droplets and insulin sensitivity in humans

(2008) V. Puri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

COPI Complex Is a Regulator of Lipid Homeostasis

(2008) Mathias Beller et al.   PLOS BIOLOGY