Epigenetic regulation of the expression of Il12 and Il23 and autoimmune inflammation by the deubiquitinase Trabid

IL-12 and IL-23 cytokines: from discovery to targeted therapies for immune-mediated inflammatory diseases

(2015) Michele W L Teng et al.   NATURE MEDICINE

TAK1 control of cell death

(2014) S R Mihaly et al.   CELL DEATH AND DIFFERENTIATION

Loss of Trabid, a New Negative Regulator of the Drosophila Immune-Deficiency Pathway at the Level of TAK1, Reduces Life Span

(2014) Merennege Dilan Anush Fernando et al.   PLoS Genetics

The Dendritic Cell Lineage: Ontogeny and Function of Dendritic Cells and Their Subsets in the Steady State and the Inflamed Setting

(2013) Miriam Merad et al.   Annual Review of Immunology

Enhanced IL-12p40 production in LPS-stimulated macrophages by inhibiting JNK activation by artemisinin

(2012) Young-Chang Cho et al.   ARCHIVES OF PHARMACAL RESEARCH

Cell-Type-Specific Control of Enhancer Activity by H3K9 Trimethylation

(2012) Yina Zhu et al.   MOLECULAR CELL

Regulation of chromatin by histone modifications

(2011) Andrew J Bannister et al.   CELL RESEARCH

An ankyrin-repeat ubiquitin-binding domain determines TRABID's specificity for atypical ubiquitin chains

(2011) Julien D F Licchesi et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

IL-17 receptor signaling and T helper 17-mediated autoimmune demyelinating disease

(2011) Jarod Zepp et al.   TRENDS IN IMMUNOLOGY

A Feed-Forward Circuit Controlling Inducible NF-κB Target Gene Activation by Promoter Histone Demethylation

(2010) Dominic van Essen et al.   MOLECULAR CELL

Engineered diubiquitin synthesis reveals Lys29-isopeptide specificity of an OTU deubiquitinase

(2010) Satpal Virdee et al.   Nature Chemical Biology

Regulation of Adaptive Immunity by the Innate Immune System

(2010) A. Iwasaki et al.   SCIENCE

Regulation of Th17 cell differentiation and EAE induction by MAP3K NIK

(2009) W. Jin et al.   BLOOD

RAD6-Mediated Transcription-Coupled H2B Ubiquitylation Directly Stimulates H3K4 Methylation in Human Cells

(2009) Jaehoon Kim et al.   CELL

Linking DNA methylation and histone modification: patterns and paradigms

(2009) Howard Cedar et al.   NATURE REVIEWS GENETICS

Trabid, a new positive regulator of Wnt-induced transcription with preference for binding and cleaving K63-linked ubiquitin chains

(2008) H. Tran et al.   GENES & DEVELOPMENT

Erasing the methyl mark: histone demethylases at the center of cellular differentiation and disease

(2008) P. A.C. Cloos et al.   GENES & DEVELOPMENT

LPS and Poly I:C Induce Chromatin Modifications at a Novel Upstream Region of the IL-23 p19 Promoter

(2008) Stacey Garrett et al.   INFLAMMATION

IL-12– and IL-23–modulated T cells induce distinct types of EAE based on histology, CNS chemokine profile, and response to cytokine inhibition

(2008) Mark A. Kroenke et al.   JOURNAL OF EXPERIMENTAL MEDICINE